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Tigers vs Reds Prediction, Pick, MLB Odds for Saturday, April 25

Tigers vs Reds Prediction, Pick, MLB Odds for Saturday, April 25 article feature image
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Katie Stratman-Imagn Images. Pictured: Tigers RF Kerry Carpenter

The Cincinnati Reds host the Detroit Tigers on April 25, 2026. First pitch from Great American Ball Park is scheduled for 7:15 p.m. ET. The game will be broadcast on FOX.

The Tigers are favored by -110 on the moneyline and by -1.5 on the run line. The Reds are -110 on the moneyline and +1.5 on the run line. The total is set at 9.5 runs.

Find my MLB picks and Tigers vs Reds prediction below, as well as probable pitchers, weather report, and more.


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Tigers vs Reds Prediction

  • Tigers vs Reds Pick: Over 9.5 (+100)

My Tigers vs Reds best bet is Over 9.5 total runs in this game. Make sure to find the best odds by checking our live MLB odds page.


Tigers vs Reds Odds

Tigers Logo
Saturday, April 25
7:15 p.m. ET
FOX
Reds Logo
Tigers Odds
SpreadTotalMoneyline
-1.5
+150
9.5
100o / -120u
-110
Reds Odds
SpreadTotalMoneyline
+1.5
-185
9.5
100o / -120u
-110
Odds via BetMGM. Get up-to-the-minute MLB odds here.
BetMGM Logo
  • Tigers vs Reds moneyline: Tigers -110, Reds -110
  • Tigers vs Reds over/under: 9.5 (+100o / -120u)
  • Tigers vs Reds spread: Tigers -1.5 (+150), Reds +1.5 (-185)

Tigers vs Reds Probable Pitchers

RHP Jack Flaherty (DET)StatRHP Brady Singer (CIN)
0-1W-L1-1
0.3fWAR (FanGraphs)0.3
3.47 / 4.86ERA / xERA5.32 / 5.18
4.59 / 5.86FIP / xFIP4.57 / 4.54
3.7K-BB%8.2
30.5GB%40.0
.267BABIP.354
97Stuff+93
84Location+97

Tigers vs Reds MLB Betting Preview

Our own Sean Zerillo projects an edge on the total for this matchup

While the consensus line sits at 9.5, Zerillo projects around 10.15 runs for this game, representing a 5.4% edge against the market, making the over the best choice with a B grade on our system.

Also, the number of bets and percentage of money show increasing support for this pick heading into tonight's first pitch.

As a reminder, you can see all of Zerillo's MLB game projections with an Action PRO Subscription. Find his projected lines every day on the PRO Projections tab.


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Tigers vs Reds Pick, Betting Analysis

These teams are coming off a 17-run game yesterday, and both offenses have been raking recently.

Detroit ranks fifth in wRC+ with 135 over the last seven days, while Cincinnati ranks 13th with 113 — which is high for them considering the Reds are still 27th overall this season with an 82 rating.

Jack Flaherty takes the mound today, and the difference between his expected metrics and actual numbers in ERA and FIP suggests an upcoming regression.

Plus, he's only getting 30.5% of ground balls, which is not great when playing at the Great American Ballpark, the second-best venue for homers in the past three years.

Detroit has five batters with OPS above .900 in the last seven days: Kerry Carpenter, Riley Greene, Jahmai Jones, Spencer Torkelson and Kevin McGonigle.

Against the righty Brady Singer, who's allowing a .354 BABIP this season, the lefties Carpenter, Greene and McGonigle should do very well.

Pick: Over 9.5 (+100, BetMGM)

Playbook

Tigers vs Reds Weather


Get the latest coverage on MLB Weather.
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