The Seattle Mariners (5-9) host the Houston Astros (6-8) on April 11, 2026. First pitch from T-Mobile Park is scheduled for 9:40 p.m. EDT. The game will be broadcast on SEAM.
The Mariners are favored by -152 on the moneyline and -1.5 on the run line. The Astros are +128 on the moneyline and +1.5 on the run line. The total is set at 7.5 runs.
Find my MLB picks and Astros vs Mariners prediction below, as well as probable pitchers, weather report, and more.
Astros vs Mariners Predictions, Pick
- Astros vs Mariners Pick: Luis Castillo Over 5.5 Strikeouts
Astros vs Mariners Odds, Run Line, & Spread
| Astros Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -166 | 7.5 -102o / -120u | +128 |
| Mariners Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +138 | 7.5 -102o / -120u | -152 |
Astros vs Mariners Polymarket Odds
Current odds: HOU 42% · SEA 59% · MLB
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Astros vs Mariners Player Prop Pick
By Derek Carty
THE BAT X is forecasting 6.20 strikeouts for Castillo.
Oddsmakers are implying 5.44 strikeouts, so I believe there is value.
If you take the over, you’d be projected to win 59% of the time, resulting in a 28% ROI with an expected value of $28.28 (based on a $100 wager).
This play is good down to at least -107.
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Pick: Luis Castillo Over 5.5 Strikeouts
