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MLB Best Bets Today: Predictions & Picks for Astros vs Blue Jays, Yankees vs Tigers, More for Tuesday, June 23

MLB Best Bets Today: Predictions & Picks for Astros vs Blue Jays, Yankees vs Tigers, More for Tuesday, June 23 article feature image
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We have a full 15-game slate on Tuesday, starting with Astros vs Blue Jays at 4:07 PM at Rogers Centre on MLB.TV, and closing with Athletics vs Giants at 9:45 PM ET at Oracle Park on MLB.TV.

Our experts have analyzed the matchups and found great options for Tuesday, June 23.

Below are 5 expert MLB best bets today.


MLB Best Bets Today

The team logos in the table below represent each of the matchups that our MLB betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.

GameTime (ET)Pick
Houston Astros LogoToronto Blue Jays Logo
4:07 PM
New York Yankees LogoDetroit Tigers Logo
6:40 PM
Chicago Cubs LogoNew York Mets Logo
7:10 PM
Boston Red Sox LogoColorado Rockies Logo
8:40 PM
Oakland Athletics LogoSan Francisco Giants Logo
9:45 PM
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game.

Tanner McGrath's Astros vs Blue Jays Best Bet

Houston Astros Logo
46196
4:07 PM ET
MLB.TV
Toronto Blue Jays Logo
Astros ML (+110 or Better)
FanDuel Logo

By Tanner McGrath

If you're struggling to break down this game, it would be wise to use Sean Zerillo's new BARTOLO tool.

Here's a sneak peek of what you can get with an Action PRO subscription.

Click Here To Get BARTOLO Image

While Peter Lambert is not a very good pitcher, I think he actually gets a bit of a bad rap. He’s running an above-average strikeout minus walk rate (12.6%), has accumulated 1.0 fWAR, and his earned run indicators indicate a slightly below-average starting pitcher.

I actually prefer Lambert to Shane Bieber, given how poorly Bieber struggled in his rehab starts — he’s making his 2026 MLB debut today. Across four starts at the High-A and Triple-A levels, Bieber allowed 13 earned runs on 24 hits across 15 innings, with just 11 strikeouts to five walks.

I doubt that Bieber is in top form at the moment. I don’t even know if he’s fully healthy.

Meanwhile, as you can see above, Zerillo power rates Houston’s bullpen as the best in the league.

Both lineups should be power rated about the same based on both forward-facing projections and past production, meaning that Houston should (surprisingly) have the pitching advantage across all nine innings in this matchup.

Yet we can get the Astros at more-than-reasonable plus-money prices. Zerillo doesn't project any value on Houston in this matchup, but I'll take a shot with them in Tuesday's afternoon ballgame.

Pick: Astros ML (+110 or Better)



Grant Neiffer's Yankees vs Tigers Best Bet

New York Yankees Logo
46196
6:40 PM ET
MLB.TV
Detroit Tigers Logo
Spencer Torkelson Home Run (+475 or Better)
FanDuel Logo

By Grant Neiffer

Carlos Rodon has been great this season at suppressing righty power, but he's due for some pretty heavy negative regression.

His underlying numbers aren't great, with heavy fly balls and hard contact, and he's been a plus matchup the last 4 seasons for righty power.

Tork is due for some positive regression, and I have the true odds here around +450, making this a great bet.

Pick: Spencer Torkelson Home Run (+475 or Better)



Jon Anderson's Cubs vs Mets Best Bet

Chicago Cubs Logo
46196
7:10 PM ET
MLB.TV
New York Mets Logo
Over 8.5 (-110 or Better)
FanDuel Logo

By Jon Anderson

How do you bet on a game with two pitchers like this? It gets pretty tough to figure out where to go.

Edward Cabrera and Kodai Senga are both capable of getting strikeouts and not allowing hits. They have good stuff, but just can't command it. They usually won't get hit around the ballpark all night long, but they'll allow baserunners via the walk and leave themselves vulnerable to crooked numbers when extra-base hits come with men on base.

I think both of these guys will walk multiple hitters. They almost always do, and both of these lineups know how to take a walk.

My sim model likes a lot of scoring in this one. I would recommend the over 8.5 pretty heavily. And I like the Mets to score the bulk of the runs simply because of the current state of the Cubs' pitching staff — Cabrera will struggle to get through five innings here, and the bullpen behind him is in rough shape.

Pick: Over 8.5 (-110 or Better)



Ryan Minion's Red Sox vs Rockies Best Bet

Boston Red Sox Logo
46196
8:40 PM ET
MLB.TV
Colorado Rockies Logo
Red Sox F5 -0.5 (-130 or Better)
FanDuel Logo

By Ryan Minion

In his first 13 starts for the Red Sox, Sonny Gray has been phenomenal, posting an impressive 3.12 ERA and an efficient 1.18 WHIP.

While Gray has had a very up-and-down last few seasons, often struggling to find any form of consistency on the bump, the righty veteran has finally found stable form on the mound over his first season in Boston thus far.

While the Red Sox right-hander is having a breakout resurgence to kick off his 2026 campaign, the same can't be said of the Rockies’ youngster Sean Sullivan.

Colorado’s 23-year-old rookie has made just two starts in the Big Leagues, having recorded an atrocious 10.29 ERA along with a remarkably inefficient 1.86 WHIP as well.

After pitching three scoreless frames in his MLB debut, Sullivan surrendered eight earned runs (ER) across four frames in his second outing versus the Cubs.

While his small sample in the Major Leagues is obviously quite misleading in regard to his metrics on the bump thus far, the left-hander’s last outing could definitely be some cause for concern.

In this matchup, the Red Sox have a massive pitching edge on the mound. I feel great backing the Red Sox to cover their first five runline.

Pick: Red Sox F5 -0.5 (-130 or Better)



Sean Zerillo's Athletics vs Giants Best Bet

Oakland Athletics Logo
46196
9:45 PM ET
MLB.TV
San Francisco Giants Logo
Athletics ML (-105 or Better)
FanDuel Logo

By Sean Zerillo

I set the Athletics as -115 favorites on Tuesday night against their former cross-bay rivals, and I'd anticipate this line will close around a pick'em; bet the A's at plus money, down to -105.

Robbie Ray (my SP#182) has more name-brand value than Aaron Civale (SP# 193), but both starters rank near the bottom of my pitcher rankings (5.29 and 4.74 SIERA and 5.68 and 5.13 xFIP over their past five starts); this matchup comes down to the lineups and bullpens.

Both teams rate poorly defensively and on the basepaths (my bottom two teams, at 29th and 30th), but the Athletics rank among my best offenses for both power and patience, whereas the Giants have a better contact rate but much less power and process.

Accounting for all offensive factors, including wRC+ projections, and my grades for contact, power, and eye, I rank the Athletics as my second-best offense team, and the Giants 27th. Moreover, I give the Athletics the slight bullpen advantage (20th vs. 25th) once the game moves away from these shaky starters.

Pick: Athletics ML (-105 or Better)



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