Saturday features our first full 15-game slate of the MLB season!
So, it goes without saying that our staff of MLB betting experts has found some value on the board.
Read on for our MLB Picks and best bets today for Saturday, March 28.
MLB Picks, Best Bets Today — Saturday, March 28
The team logos in the table below represent each of the matchups that our MLB betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Game | Time (ET) | Pick |
|---|---|---|
  | 2:15 PM | |
  | 3:08 PM | |
  | 9:40 PM | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game. | ||
Rays vs Cardinals Pick
By Sean Paul
I want to bet on the Joe Boyle portion of the game.
The Cardinals have a slight bullpen edge with Matt Svanson, Riley O'Brien, JoJo Romero, and Ryne Stanek at the back end.
That could be the difference in the latter innings, but Boyle should outduel Michael McGreevy in the early going.
Read Paul's full Rays-Cardinals breakdown here:
Pick: Rays F5 ML (-110 or Better)
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Athletics vs Blue Jays Player Prop
By Derek Carty
THE BAT X is forecasting 3.23 strikeouts for Jeffrey Springs, so I believe there is value here.
If you take the Under, you’d be projected to win 61% of the time, resulting in a 25% ROI.
Based on a $100 wager, the expected value here would be $24.56.
Love THE BAT X? Get all of Carty’s sports betting projections at EV Analytics!
Pick: Jeffrey Springs Under 3.5 Strikeouts (+100 or Better)
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Yankees vs Giants Best Bet
Is the third time the charm for the Giants to get a win? Not today.
The Yankees have Will Warren on the mound against Tyler Mahle. Mahle's ERA exceeded Warren's in 2025, 2.18 to 4.44. However, Warren's xFIP and SIERA were better than Mahle's, and he is a young, fireballer with massive upside.
While that may not come to fruition in a given start or month, Warren, in a vacuum, is the better starting pitcher for today.
Mahle is also not as built up as Warren. Warren threw 25 1/3 innings through six starts in Spring Training, while Mahle threw just 10 innings through four outings.
Oddly, Warren's stats are better in the hitter-friendly confines of Yankee Stadium, but his career innings at home are a small sample, allowing us to ignore that for now. However, that could come into use later if the trend carries over into 2026…
The Yankees possess the much better offense in this matchup (as they have the past two) and will face a bullpen they have seen almost the entirety of midgame. The Giants have utilized eight different relievers thus far, while the Yankees have deployed six.
Unless Tyler Mahle's horseshoe from last season continues to ride in his rear, regression and the opposing offense could arrive in an ugly fashion.
Check out Kev's full Yankees-Giants breakdown here:
Pick: Yankees ML (-130 or Better)
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