We love Wednesdays on the diamond.
There are games to bet on all day, from Padres-Pirates at Noon to Tigers-Twins after Sundown.
Check out our four best bets for today's games below.
MLB Picks, Predictions
The team logos in the table below represent the matchups our MLB betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Game | Time (ET) | Pick |
|---|---|---|
  | 2:35 PM | |
  | 12:35 PM | |
  | 1:35 PM | |
  | 7:05 PM | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game. | ||
Mariners vs. Rangers Moneyline Picks
By Sean Zerillo
The Seattle Mariners will look to avoid an early series sweep against a division rival in Arlington as they take on the Rangers on Wednesday afternoon.
Bryan Woo (projected FIP range of 3.38 to 3.60; projected K-BB% of 19.3% to 21.3%) projects to be a tier above MacKenzie Gore (projected ranges of 3.59 to 3.86 and 17.3% to 18.8%).
Still, Gore has slightly modified his pitch mix since joining the Rangers in a trade this offseason, reducing his slider usage (from 15.3% career to 6.7%) while mixing in a cutter (8.4%) and a sinker (5.1%), and he's tossed consecutive solid outings (combined 11 1/3 IP, 8 H, 5 R, 3 BB, 16 K)
Even if the starters are now more comparable than their projections indicate, the Mariners still have a distinct bullpen advantage; Andres Munoz, Matt Brash, Jose A. Ferrer, Gabe Spieier, and Eduard Bazardo all project for a sub 3.7 weighted FIP (four below 3.25) while the Rangers only carry two bullpen arms (Chris Martin, projected 3.55) and Robert Garcia (3.69) who rate as above average relievers.
The Rangers' lineup projects better than the Mariners', even though Seattle's projected splits are normalized by the addition of lefty-killer Rob Refsnyder as a platoon bat. More importantly, however, is that the offensive gap between these teams is somewhat negated by the Mariners' advantages both defensively and on the basepaths.
Take the Mariners to -133 pregame, and consider a live wager shortly before or as Gore exits; the M's should have a sizeable pitching advantage from that point forward.
Read Sean Zerillo's full Opening Pitch column for Wednesday here:
Pick: Mariners ML (-133 or Better) | Under 7 (-115 or Better)
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Padres vs. Pirates Moneyline Prediction
By Sean Paul
I'm rolling with the Pirates.
They match up well against Michael King, as Brandon Lowe, Oneil Cruz, and Ryan O'Hearn should be able to handle the right-handed pitcher.
The line shows two evenly matched teams, but the Pirates look like the better squad.
Read Sean's full Padres-Pirates breakdown here:
Pick: Pirates ML (-130 or Better)
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Brewers vs. Red Sox Over/Under Picks
This game triggered one of our Action PRO betting systems, powered by Evan Abrams.
In the early months of the MLB season (March and April), cold weather (between 1 and 50 degrees) creates ideal conditions for unders.
Pitchers tend to be ahead of hitters at the start of the season, and colder air can suppress offensive production by reducing ball carry.
This system further isolates day games (12 PM to 4 PM) when shadows and cool starts give pitchers an additional edge — especially as hitters may take longer to get loose.
Taken together, these filters identify a recurring edge that has yielded a positive long-term ROI when consistently betting the under.
It is bone-chilling cold up in the Northeast during this time of year, and Fenway is no different. We’re expecting temperatures in the mid-40s for Wednesday’s game with winds blowing in from right field — not ideal for hitting.
Based on the weather report, BallParkPal projects a -51% home run factor, which should keep scoring down.
Also, I think Sonny Gray looked excellent in his last start against San Diego, tossing six shutout innings while allowing only two hits. He’s a guy who has had struggles with the long ball over the past two seasons (1.19 HR/9 allowed, 14.4% HR/FB rate allowed), so Wednesday’s weather should help him tremendously.
Want more PRO betting systems? Sign up for an Action PRO subscription today:
Pick: Under 7.5 (-115 or Better)
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Athletics vs. Yankees Total Picks
Our own Sean Zerillo projects a decent edge on the Over in this matchup.
While the consensus line sits around 8.5 with low juice toward the Over, Zerillo projects nearly 9.1 runs for the game, representing a nearly 3% edge against the market.
As a reminder, you can see all of Zerillo's MLB game projections with an Action PRO Subscription. Find his projected lines every day on the PRO Projections tab.
Pick: Over 8.5 (-112 or Better)
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