We have a loaded Friday slate on the diamond.
As a result, our staff of MLB betting experts has bets for almost every game.
Here's a few of our favorites.
MLB Picks, Predictions Today
The team logos in the table below represent the matchups our MLB betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Game | Time (ET) | Pick |
|---|---|---|
  | 6:10 PM | |
  | 7:10 PM | |
  | 9:40 PM | |
 | All Day | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game. | ||
Orioles vs Guardians Over/Under Picks
Our own Sean Zerillo projects a nice edge on the Under in this matchup's total.
While the consensus line sits around 8, Zerillo projects 7.27 runs for this game, representing a 3.7% edge against the market and a B- grade in our system.
As a reminder, you can see all of Zerillo's MLB game projections with an Action PRO Subscription. Find his projected lines every day on the PRO Projections tab.
Pick: Under 8 (7.5 -110 or Better)
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Brewers vs Marlins Moneyline Picks
By Evan Abrams
This game triggered one of our Action PRO betting systems:
The Brewers just wrapped up a series against the Toronto Blue Jays, so they arrive in Miami with their normal routines and pitching schedules fully intact — no significant time-zone disruption or long cross-country flight. The market, however, tends to undervalue this edge when facing the Marlins in a series opener, creating value on the visitors.
Kyle Harrison gets the ball for Milwaukee, while Janson Junk starts for Miami. The Brewers have gotten off to a solid start and enter this series opener in a strong position to capitalize on their fresh travel situation.
Miami has struggled to meet expectations early in 2026, going 3-7 over their last 10 ballgames, and the public often overestimates the Marlins’ home advantage in these spots while underappreciating how well-rested and routine-oriented the visiting team can be. This system has repeatedly found value by fading those assumptions in the first game of the Marlins series.
The edge comes from a subtle but persistent market inefficiency: bettors and oddsmakers overestimate the impact of “minimal travel” while underpricing teams like the Brewers, who are simply playing their normal game without adjustment issues.
While no system guarantees a win in any single game, this Brewers-Marlins opener checks every box the system looks for — a Marlins series debut against a visitor coming straight from an Eastern Time Zone game.
Pick: Brewers ML (-110 or Better)
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Rangers vs Mariners Total Picks
This bet is based on four things:
- Jacob deGrom
- Logan Gilbert
- T-Mobile Stadium
- Terrible hitting weather
deGrom looks good. In his last start against the Dodgers, he allowed a first-pitch home run to Shohei Ohtani before tossing six shutout innings with nine strikeouts.
The fastball will never get back to the 99 MPH average it once was, but he doesn’t want to throw it that hard to avoid injury. But his four-seam is still sitting around 97 MPH, and his slider is still one of the league’s best. Plus, he’s throwing more changeups, which drastically helps his batted-ball profile.
Meanwhile, Logan Gilbert looks just as good. Houston is as hot as any team in the league, yet Seattle’s Ace tossed seven one-run innings against the Astros with seven strikeouts.
The fastball is elite. He throws it 95 MPH at the top of the zone with crazy extension, forcing a 37% CSW rate.
T-Mobile Stadium is the worst run-scoring environment in the Majors, and the weather will do no favors to those in the batter’s box on Friday, with temperatures in the low-50s and winds blowing in from left field. BallParkPal projects a -20% run-scoring factor behind a -17% home run factor and a -26% extra-base hit factor.
These two teams faced off in the same starting pitching matchup 11 days ago, finishing with a 2-1 score. I’m expecting more of the same.
Pick: Under 6.5 (-115 or Better)
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Zerillo's Full Action App Card
Need more picks for Friday's action? It's always wise to see what Zerillo is betting on!
Follow him in the Action Network App, and get a PRO subscription to ensure you get real-time alerts every time he places a wager.
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