The Milwaukee Brewers host the San Diego Padres on Tuesday, May 12. First pitch from American Family Field is scheduled for 7:40 p.m. ET. The game will be broadcast on BREW and MLB.TV.
The Brewers are favored by -138 on the moneyline and by -1.5 on the run line. The Padres are +118 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.
Find my MLB picks and Padres vs Brewers prediction below, as well as probable pitchers, weather report, and more.
San Diego Padres vs Milwaukee Brewers Prediction, Picks
- Padres vs Brewers Pick: Andrew Vaughn Over 0.5 Home Runs (+520 · FanDuel)
My Padres vs Brewers best bet is on Vaughn to record 1+ home runs. Make sure to find the best odds by checking our live MLB odds page.
Padres vs Brewers Odds, Betting Line, Over/Under
| Padres Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -171 | 9 -103o / -117u | +123 |
| Brewers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +141 | 9 -103o / -117u | -149 |
- Padres vs Brewers Moneyline: Padres ML +123, Brewers ML -149
- Padres vs Brewers Over/Under: 9
- Padres vs Brewers Run Line: Brewers -1.5 (+141), Padres +1.5 (-171)
Padres vs Brewers Projected Starting Pitchers
| Matt Waldron | Stat | Brandon Sproat |
|---|---|---|
| 1-1 | W-L | 0-2 |
| -0.1 | fWAR (FanGraphs) | -0.3 |
| 7.71 / 3.53 | ERA / xERA | 5.87 / 5.05 |
| 5.42 / 4.59 | FIP / xFIP | 5.99 / 4.71 |
| 11.6 | K-BB% | 9.2 |
| 46.8 | GB% | 37.5 |
| .333 | BABIP | .293 |
| 94 | Stuff+ | 100 |
| 107 | Location+ | 93 |
Padres vs Brewers Pick, MLB Player Prop
By Derek Carty
THE BAT X is forecasting 0.19 home runs for Andrew Vaughn. Oddsmakers are implying 0.15 home runs, so I believe there is value here.
If you take the over, you'd be projected to win 17% of the time, resulting in a 27% ROI with an expected value of $26.98 (based on a $100 wager).
This play is good down to at least +550.
Pick: Andrew Vaughn Over 0.5 Home Runs (+520)
Padres vs Brewers Start Time, TV Info, Channel, Streaming, Location
- Location: American Family Field, Milwaukee, WI
- Date: Tuesday, May 12, 2026
- First Pitch: 7:40 p.m. ET
- TV: Padres.TV, Brewers.TV
- Padres Starting Pitcher: Matt Waldron (1-1, 7.71 ERA)
- Brewers Starting Pitcher: Brandon Sproat (0-2, 5.87 ERA)
