STL FC vs. San Jose Odds & Betting Predictions - September 21, 2025

STL FC at San Jose

2:30 am

St. Louis City

8-18-8

3

3 - 1

San Jose Earthquakes

11-15-8

1

MatchupOpenSpreadTotalMoneyline
STL FC 8-18-8	+1.5	+0.5+105	o3.5-125	+295
San Jose 11-15-8	u2.5	-0.5-150	u3.5+103	-143

location pin

Sunday 2:30 a.m.

September 21, 2025

PayPal ParkSan Jose, CA

MLS Public Betting

San Jose are 0-5 in their last 5 games.
San Jose are 0-4 in their last 5 games against the spread
San Jose are 11-4 in their road games against the spread
The totals have gone OVER in 4 of San Jose' last 5 games
The totals have gone OVER in 10 of San Jose' 17 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
San Jose	16-15-3	5-11-1	11-4-2	4-10-1	12-5-2
STL FC	13-16-5	3-12-2	10-4-3	2-7-1	11-8-4

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
San Jose	18-12-4	10-5-2	8-7-2	10-4-1	8-8-3
STL FC	17-15-2	8-8-1	9-7-1	4-5-1	13-9-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
San Jose	11-15	5-6-6	6-9-2	5-5-5	6-10-3
STL FC	8-18	4-7-6	4-11-2	3-2-5	5-15-3

date	opponent	score	spread	over/under	moneyline
Sep 14th	LAN	L 2-4	+1.5 L	O 3.5	LAN +220
Aug 31st	@ATX	L 1-3	+0.5 L	O 3.5	ATX +227
Aug 24th	@HOU	W 2-1	+0.5 W	U 3	SJ +225
Aug 17th	SAN	L 1-2	-0.5 L	U 3	SAN -106
Aug 10th	VAN	W 2-1	-0.25 W	U 3	SJ +165

M. López
DEF
Knock
Out Indefinitely

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STL FC

San Jose

11

Fouls

13

9

Shots

18

3

Corners

11

2

Offsides

0

0

Red Cards

0

1

Yellow Cards

3

6

Shots On Goal

10

43%

Possession Time

57%

STL FC

Goalkeeping

San Jose

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MatchupOverUnder
STL FC 8-18-8	N/A	N/A
San Jose 11-15-8	N/A	N/A