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Buffalo vs. DePaul Odds & Betting Predictions - November 12, 2025

Buffalo at DePaul

1:00 am • ESPN+

Buffalo Bulls

14-8
66
66 - 53

DePaul Blue Demons

12-10
53

Buffalo at DePaul Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Buffalo
14-8
+17.5
+18.5-110
o153.5-110
+1400
DePaul
12-10
u154.5
-18.5-110
u153.5-110
-2800
location pinWednesday 1:00 a.m.
November 12, 2025
Wintrust ArenaChicago
Buffalo vs. DePaul Expert Picks
Mjaybrod
Mjaybrod
Last 30d: 64-65-3 (+6.2u)
BUFF u67.5-120
0.83u
Spraying team totals

Prop Odds Comparison

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Line Movement Tracker

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Buffalo vs. DePaul Public Betting Percentages

Away Logo

Buffalo

Public

Home Logo

DePaul

87%

Bets%

13%

Money%

NCAAB Public Betting Right Arrow

Betting Trends

  • DePaul are 2-3 in their last 5 games.
  • DePaul are 4-1 in their last 5 games against the spread
  • DePaul are 7-2 in their road games against the spread
  • The totals have gone OVER in 2 of DePaul' last 5 games
  • The totals have gone OVER in 5 of DePaul' 13 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
DePaul		15-78-57-27-48-3
Buffalo		12-85-57-38-34-5

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
DePaul		7-155-82-74-73-8
Buffalo		12-87-35-56-56-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
DePaul		12-10N/AN/A10-12-9
Buffalo		14-8N/AN/A9-23-6

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 8thSTNHW 72-64-22.5 LU 147DEP -5000
Nov 4thCHSW 92-62-24.5 WO 143.5DEP -8000
Apr 1st@CINL 61-83+9.5 LO 141.5CIN +360
Mar 13th@CREIL 81-85+12.5 WO 142.5CREI +650
Mar 12th@GTWNW 71-67+4.5 WU 144.5DEP +175

Buffalo vs. DePaul Injury Updates

Buffalo Injuries

    DePaul Injuries

    • Jeremy Lorenz
      F

      Lorenz is out with hip

      Out

    • Amsal Delalic
      G

      Delalic is out for season with knee

      Out for Season

    See more NCAAB Injuries Right Arrow
    Team Stats

    20-52 (38%)
    Field Goals
    17-51 (33%)
    19-27 (70%)
    Free Throws
    10-20 (50%)
    7-17 (41%)
    3P
    9-25 (36%)
    32
    Rebounds
    36
    10
    Assists
    13
    11
    Turnovers
    18
    12
    Steals
    4
    4
    Blocks
    3
    18
    Fouls
    22

    Buffalo vs. DePaul Odds Comparison

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    Buffalo at DePaul Team Totals

    MatchupOverUnder
    Buffalo
    14-8
    N/A
    N/A
    DePaul
    12-10
    N/A
    N/A