Cincinnati vs. Clemson Odds & Betting Predictions - December 21, 2025

Cincinnati at Clemson

8:00 pm • ESPN

Cincinnati Bearcats

11-11

65 - 68

Clemson Tigers

18-4

MatchupOpenSpreadTotalMoneyline
Cincinnati 11-11	+6.5	+4-110	o140.5-108	+154
Clemson 18-4	u137.5	-4-110	u140.5-110	-185

Sunday 8:00 p.m.

December 21, 2025

Bon Secours Wellness ArenaGreenville

CIN +5.5-105

0.95u

Cincinnati vs Clemson: Take the Points?
Christian Odjakjian•
Dec 21, 2025 UTC

See more NCAAB Coverage

No props found

NCAAB Public Betting

Clemson are 4-1 in their last 5 games.
Clemson are 4-1 in their last 5 games against the spread
Clemson are 7-1 in their road games against the spread
The totals have gone OVER in 1 of Clemson' last 5 games
The totals have gone OVER in 4 of Clemson' 14 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Clemson	14-8	7-7	7-1	12-8	2-0
Cincinnati	9-13	7-7	2-6	6-5	3-7

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Clemson	9-13	4-10	5-3	8-12	1-1
Cincinnati	5-16-1	3-10-1	2-6	2-8-1	2-8

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Clemson	18-4	N/A	N/A	18-2	0-2
Cincinnati	11-11	N/A	N/A	9-2	1-9

date	opponent	score	spread	over/under	moneyline
Dec 17th	SCAR	W 68-61	-12.5 L	U 142	CLEM -900
Dec 13th	MER	W 70-63	-22.5 L	U 152	CLEM -8238
Dec 9th	@BYU	L 64-67	+4.5 W	U 152.5	BYU +185
Dec 4th	@ALA	L 84-90	+8.5 W	O 165.5	ALA +350
Nov 29th	AAMU	W 92-56	-27.5 W	O 141.5	CLEM -20000

Jalen Haynes
F
Haynes is questionable with lower body
Questionable
Sencire Harris
G
Harris is questionable with illness
Questionable
Moustapha Thiam
C
Thiam is questionable with undisclosed
Questionable
Shon Abaev
G
Abaev is questionable with undisclosed
Questionable

Zac Foster
G
Foster is out for season with knee
Out for Season

See more NCAAB Injuries

Cincinnati

Clemson

22-58 (38%)

Field Goals

24-50 (48%)

11-15 (73%)

Free Throws

10-14 (71%)

10-25 (40%)

10-20 (50%)

Rebounds

Assists

Turnovers

Steals

Blocks

Fouls

Could not load odds

See more NCAAB Odds

MatchupOverUnder
Cincinnati 11-11	N/A	N/A
Clemson 18-4	N/A	N/A

Cincinnati vs. Clemson Odds & Betting Predictions - December 21, 2025

Cincinnati at Clemson

Cincinnati Bearcats

Clemson Tigers

Cincinnati at Clemson Odds

Spread, Total, Moneyline

Cincinnati vs. Clemson Previews & Analysis

Cincinnati vs Clemson: Take the Points?

Prop Odds Comparison

Line Movement Tracker

Cincinnati vs. Clemson Public Betting Percentages

Cincinnati

Public

Clemson

Bets%

Money%

Betting Trends

Matchup History

Against the Spread (ATS) History

Over/Under History

Straight-Up (ML) History

Last 5 Matchups

Cincinnati vs. Clemson Injury Updates

Cincinnati Injuries

Clemson Injuries

Cincinnati vs. Clemson Odds Comparison

Cincinnati at Clemson Team Totals