Clemson vs. Alabama Odds & Betting Predictions - December 4, 2025

Clemson at Alabama

12:15 am • ESPNU

Clemson Tigers

10-3

84 - 90

Alabama Crimson Tide

9-3

MatchupOpenSpreadTotalMoneyline
Clemson 10-3	+9	+8.5-108	o165.5-115	+350
Alabama 9-3	u164.5	-8.5-112	u165.5-108	-455

Thursday 12:15 a.m.

December 04, 2025

Coleman ColiseumTuscaloosa

CLEM +10.5-115

0.87u

Article up

Over 167.5-120

Clemson vs Alabama: Tigers Can Keep This Close
Sean Paul•
Dec 3, 2025 UTC
How to Bet 5 ACC/SEC Challenge Matchups on Wednesday
Action Network Staff•
Dec 3, 2025 UTC

See more NCAAB Coverage

No props found

NCAAB Public Betting

Alabama are 4-1 in their last 5 games.
Alabama are 1-4 in their last 5 games against the spread
Alabama are 3-0 in their road games against the spread
The totals have gone OVER in 2 of Alabama' last 5 games
The totals have gone OVER in 4 of Alabama' 9 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Alabama	5-7	2-7	3-0	2-4	2-2
Clemson	6-7	3-6	3-1	4-7	2-0

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Alabama	6-6	4-5	2-1	4-2	2-2
Clemson	6-7	3-6	3-1	5-6	1-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Alabama	9-3	N/A	N/A	5-1	2-2
Clemson	10-3	N/A	N/A	10-1	0-2

date	opponent	score	spread	over/under	moneyline
Nov 27th	MD	W 105-72	-14.5 W	O 166.5	ALA -1522
Nov 26th	@UNLV	W 115-76	-14.5 W	O 181.5	ALA -1248
Nov 25th	GONZ	L 85-95	+4.5 L	O 178.5	GONZ +167
Nov 20th	@ILL	W 90-86	+2.5 W	U 181.5	ALA +120
Nov 14th	PUR	L 80-87	-3.5 L	U 172.5	PUR -162

Latrell Wrightsell
G
Wrightsell is out for season with achilles
Out for Season
Houston Mallette
G
Mallette is out for season with knee
Out for Season

Noah Williamson
C
Williamson is questionable with undisclosed
Questionable

See more NCAAB Injuries

Clemson

Alabama

29-71 (41%)

Field Goals

28-60 (47%)

22-28 (79%)

Free Throws

22-31 (71%)

4-19 (21%)

12-34 (35%)

Rebounds

Assists

Turnovers

Steals

Blocks

Fouls

Could not load odds

See more NCAAB Odds

MatchupOverUnder
Clemson 10-3	o78.5-110	u78.5-120
Alabama 9-3	o87.5-120	u87.5-110

Clemson vs. Alabama Odds & Betting Predictions - December 4, 2025

Clemson at Alabama

Clemson Tigers

Alabama Crimson Tide

Clemson at Alabama Odds

Spread, Total, Moneyline

Clemson vs. Alabama Previews & Analysis

Clemson vs Alabama: Tigers Can Keep This Close

How to Bet 5 ACC/SEC Challenge Matchups on Wednesday

Prop Odds Comparison

Line Movement Tracker

Clemson vs. Alabama Public Betting Percentages

Clemson

Public

Alabama

Bets%

Money%

Betting Trends

Matchup History

Against the Spread (ATS) History

Over/Under History

Straight-Up (ML) History

Last 5 Matchups

Alabama vs. Clemson Injury Updates

Alabama Injuries

Clemson Injuries

Clemson vs. Alabama Odds Comparison

Clemson at Alabama Team Totals