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Clemson vs. Louisville Odds & Betting Predictions - March 15, 2025

Clemson at Louisville

1:30 am • ESPN

Clemson Tigers

7-3
73
73 - 76

Louisville Cardinals

8-1
76

Clemson at Louisville Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Clemson
7-3
+1
-2.5-107
o141.5-115
-142
Louisville
8-1
u140.5
+2.5-112
u141.5-105
+120
location pinSaturday 1:30 a.m.
March 15, 2025
Spectrum CenterCharlotte
Clemson vs. Louisville Expert Picks
Gamblers Dream
Gamblers Dream
Last 30d: 4-5-0 (-7.0u)
CLEM +10.5 (Live)-112
1u
The Degenerate
The Degenerate
Last 30d: 0-0-0 (+0.0u)
LOU +1.5-102
0.49u
The Degenerates
The Degenerates
Last 30d: 98-89-5 (+1.8u)
CLEM -115
1.15u
STL ELITE
STL ELITE
Last 30d: 0-0-0 (+0.0u)
CLEM -1.5-110
3.85u
Roger Goodell
Roger Goodell
Last 30d: 39-56-1 (-12.8u)
CLEM -115
1.5u
Bet Labs
Bet Labs
Last 30d: 25-16-0 (+6.4u)
LOU +0.5 (1H)-115
1u
Royals Props
Royals Props
Last 30d: 49-48-1 (-5.0u)
V.Lakhin o11.5 Pts-120
1u
MGM
Lock & Cash
Lock & Cash
Last 30d: 10-11-2 (-2.3u)
CLEM -115
1.5u
Shane McNichol
Shane McNichol
Last 30d: 0-0-0 (+0.0u)
LOU +1.5-120
0.91u
DeadPresPicks
DeadPresPicks
Last 30d: 2-6-0 (-2.0u)
CLEM +100
0.55u

Clemson vs. Louisville Previews & Analysis

  • Clemson vs. Louisville: The ML Bet to Make article feature image

    Clemson vs. Louisville: The ML Bet to Make

    Hammering Hank•
    Mar 14, 2025 UTC
  • Friday's 3-Leg +584 NCAAB Parlay article feature image

    Friday's 3-Leg +584 NCAAB Parlay

    Dead President Picks•
    Mar 14, 2025 UTC
See more NCAAB Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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Clemson vs. Louisville Public Betting Percentages

Away Logo

Clemson

Public

Home Logo

Louisville

26%

Bets%

74%

Money%

NCAAB Public Betting Right Arrow

Betting Trends

  • Louisville are 4-1 in their last 5 games.
  • Louisville are 4-1 in their last 5 games against the spread
  • Louisville are 2-1 in their road games against the spread
  • The totals have gone OVER in 2 of Louisville' last 5 games
  • The totals have gone OVER in 3 of Louisville' 6 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Louisville		6-34-22-13-1N/A
Clemson		6-43-33-14-42-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Louisville		5-43-32-13-1N/A
Clemson		6-43-33-15-31-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Louisville		8-1N/AN/A3-1N/A
Clemson		7-3N/AN/A7-10-2

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Mar 13thSTANW 75-73-10.5 LO 143.5LOU -625
Mar 8thSTANW 68-48-10.5 WU 147.5LOU -675
Mar 6thCALW 85-68-14.5 WU 154.5LOU -1175
Mar 1stPITTW 79-68-10.5 WU 150.5LOU -550
Feb 26th@VTW 71-66-10.5 LU 147.5LOU -600
Team Stats

27-69 (39%)
Field Goals
24-55 (44%)
14-17 (82%)
Free Throws
22-27 (81%)
5-16 (31%)
3P
6-22 (27%)
33
Rebounds
34
8
Assists
12
9
Turnovers
13
10
Steals
7
2
Blocks
5
22
Fouls
19

Clemson vs. Louisville Odds Comparison

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Clemson at Louisville Team Totals

MatchupOverUnder
Clemson
7-3
o71.5-120
u71.5-110
Louisville
8-1
o69.5-125
u69.5-105