Cardinals vs. Toledo Odds & Betting Predictions - November 22, 2025
Cardinals at Toledo
7:00 pm • ESPN+Cardinals at Toledo Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Cardinals 4-8 | +29.5 | +29.5-111 | o45.5-108 | +2341 |
Toledo 8-4 | u45.5 | -29.5-109 | u45.5-111 | -7467 |

Glass BowlToledo
Cardinals vs. Toledo Expert Picks

Sean Zerillo
Last 30d: 72-64-1 (+5.7u)
BALL +28.5-115
0.29u
Greg Matherne
Last 30d: 26-15-0 (+4.8u)
BALL +28-110
0.55u
Mike Calabrese
Last 30d: 31-48-0 (-12.8u)
BALL +27.5-105
1.5u
Mike Uremovich has a recipe for being a pest. The Cardinals are outside the top 100 in plays per game and seconds between plays. 24th most run heavy team in the country. They should be getting Qua Ashley back, according to Uremovich presser yesterday. That’s a big addition to a running game that needs him. He had breakout games against New Hampshire and Akron this year, he’s the key.
You can’t throw on Toledo this year, so getting anything it the run game is key. Wazzu used a similar formula, including the QB run game. They got to 162 yards on the ground, 74 coming from Zevi Eckhaus.
And let’s not forget this is Candle as a favorite. 11-9 ATS at home in MAC play despite being the top dog for years. Lookahead spot with CMU and a spot in the title game potentially on the line next week.
BBOC G5 Deep Dive Pod
Last 30d: 12-20-0 (-6.6u)
BALL +27.5-112
1u
@Breese https://myaction.app/pXrWAaWoqYb
Babs .
Last 30d: 119-81-0 (+25.6u)
BALL +27.5-110
1u
Cardinals vs. Toledo Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Cardinals vs. Toledo Public Betting Percentages
Betting Trends
- Toledo are 5-0 in their last 5 games.
- Toledo are 5-0 in their last 5 games against the spread
- Toledo are 3-3 in their road games against the spread
- The totals have gone OVER in 3 of Toledo' last 5 games
- The totals have gone OVER in 5 of Toledo' 6 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Team Stats
335
Total Yards
404
79
Total Plays
57
4.2405063291139244
Yards Per Play
7.087719298245614
206
YDS
218
14/32
Comps/Atts
15/27
6.4375
YPA
8.074074074074074
0/2
TDs/INTs
4/2
7/42
Sacks/Yards
1/7
Cardinals vs. Toledo Odds Comparison
Could not load odds
Cardinals at Toledo Team Totals
MatchupOverUnder | ||
|---|---|---|
Cardinals 4-8 | o7.5+105 | u7.5-135 |
Toledo 8-4 | o37.5-115 | u37.5-110 |






