Cardinals vs. Hokies Odds & Betting Predictions - November 1, 2025

Cardinals at Hokies

7:00 pm • The CW

Louisville Cardinals

28

28 - 16

Virginia Tech Hokies

16

MatchupOpenSpreadTotalMoneyline
Cardinals 9-4	-15.5	-10.5-110	o52.5-112	-395
Hokies 3-9	u52.5	+10.5-110	u52.5-110	+310

location pin

Saturday 7:00 p.m.

November 01, 2025

Lane StadiumBlacksburg

LOU -10-112

1u

Under 53.5-110

0.82u

3.13% ev play to -117

Your Week 10 NCAAF Betting Cheat Sheet
Pete Ruden•
Nov 1, 2025 UTC
Louisville vs. Virginia Tech: Bet the Total in Blacksburg
Doug Ziefel•
Nov 1, 2025 UTC
College Football Week 10 Best Bets & Parlay Picks! | Big Bets On Campus LIVE
•
Oct 31, 2025 UTC
Can We Hit BIG With This College Football Moneyline Round Robin?
Collin Wilson•
Oct 31, 2025 UTC

See more NCAAF Coverage

No props found

NCAAF Public Betting

Hokies are 1-4 in their last 5 games.
Hokies are 1-4 in their last 5 games against the spread
Hokies are 1-3 in their road games against the spread
The totals have gone OVER in 2 of Hokies' last 5 games
The totals have gone OVER in 5 of Hokies' 7 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Hokies	3-9	2-5	1-3	1-4	2-5
Cardinals	4-8	1-7	3-1	2-7	2-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Hokies	5-7	5-2	0-4	4-1	1-6
Cardinals	5-7	4-4	1-3	5-4	0-3

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Hokies	3-9	N/A	N/A	2-3	1-6
Cardinals	8-4	N/A	N/A	6-3	2-1

date	opponent	score	spread	over/under	moneyline
Oct 24th	CAL	W 42-34	-6 W	O 50.5	VT -225
Oct 11th	@GT	L 20-35	+14 L	U 55.5	GT +440
Oct 4th	WF	L 23-30	-5 L	O 51	WF -205
Sep 27th	@NCST	W 23-21	+9.5 W	U 57.5	VT +290
Sep 20th	WOF	W 38-6	-34.5 L	U 51.5	-

Total

371

Total Yards

240

62

Total Plays

64

5.983870967741935

Yards Per Play

3.75

Passing

136

YDS

76

19/28

Comps/Atts

11/24

4.857142857142857

YPA

3.1666666666666665

1/1

TDs/INTs

1/0

1/5

Sacks/Yards

0/0

Rushing

235

Rush Yards

164

34

Attempts

40

6.911764705882353

YPC

4.1

3

TDs

1

Turnovers

0

Fumbles Lost

0

1

Interceptions

0

Efficiency

1/2 50%

Redzone

2/2 100%

4/11 0%

3rd Down

4/15 0%

0/1 0%

4th Down

0/2 0%

First Downs

18

Total

16

6

Pass

5

11

Rush

9

1

Penalty

2

Misc

6/52

Penalties/Yards

5/46

Could not load odds

See more NCAAF Odds

MatchupOverUnder
Cardinals 9-4	o31.5-106	u31.5-123
Hokies 3-9	o20.5-119	u20.5-108