Southern Miss vs. Louisiana Odds & Betting Predictions - October 18, 2025
Southern Miss at Louisiana
9:00 pm • ESPN+Southern Miss at Louisiana Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Southern Miss 7-4 | N/A | N/A | N/A | |
Louisiana 5-6 | N/A | N/A | N/A | |

Cajun Field at Our Lady of Lourdes StadiumLafayette
Southern Miss vs. Louisiana Expert Picks
Greg Matherne
Last 30d: 27-21-0 (+6.4u)
Under 54.5-105
0.5u
Southern Miss vs. Louisiana Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Southern Miss vs. Louisiana Public Betting Percentages
Betting Trends
- Louisiana are 2-3 in their last 5 games.
- Louisiana are 3-2 in their last 5 games against the spread
- Louisiana are 3-3 in their road games against the spread
- The totals have gone OVER in 2 of Louisiana' last 5 games
- The totals have gone OVER in 2 of Louisiana' 5 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 6-5 | 3-2 | 3-3 | 1-2 | 5-3 | |
| 5-5-1 | 4-2 | 1-3-1 | 4-3-1 | 1-2 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 7-4 | 2-3 | 5-1 | 1-2 | 6-2 | |
| 6-5 | 4-2 | 2-3 | 5-3 | 1-2 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 5-6 | N/A | N/A | 1-2 | 4-4 | |
| 7-4 | N/A | N/A | 6-2 | 1-2 |
Last 5 Matchups
Team Stats
363
Total Yards
356
58
Total Plays
75
6.258620689655173
Yards Per Play
4.746666666666667
230
YDS
135
12/17
Comps/Atts
14/27
13.529411764705882
YPA
5
1/1
TDs/INTs
0/2
0/0
Sacks/Yards
2/11
133
Rush Yards
221
41
Attempts
48
3.2439024390243905
YPC
4.604166666666667
1
TDs
1
6/43
Penalties/Yards
8/70
Southern Miss vs. Louisiana Odds Comparison
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Southern Miss at Louisiana Team Totals
MatchupOverUnder | ||
|---|---|---|
Southern Miss 7-4 | N/A | N/A |
Louisiana 5-6 | N/A | N/A |






