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Broncos vs. 49ers Odds & Betting Predictions - August 10, 2025

Broncos at 49ers

12:30 am

Denver Broncos

1-0
30
30 - 9

San Francisco 49ers

0-1
9

Broncos at 49ers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Broncos
1-0
+1.5
-6.5-109
o38.5-109
-280
49ers
0-1
u34.5
+6.5-111
u38.5-110
+240
location pinSunday 12:30 a.m.
August 10, 2025
Levi's StadiumSanta Clara

Broncos vs. 49ers Previews & Analysis

  • Top Saturday Trends, Smart Money Picks article feature image

    Top Saturday Trends, Smart Money Picks

    Alex Kolodziej•
    Aug 9, 2025 UTC
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Broncos vs. 49ers Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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Broncos vs. 49ers Public Betting Percentages

Away Logo

Broncos

Public

Home Logo

49ers

40%

Bets%

60%

Money%

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Betting Trends

  • 49ers are 2-3 in their last 5 games.
  • 49ers are 2-3 in their last 5 games against the spread
  • 49ers are 1-7 in their road games against the spread
  • The totals have gone OVER in 2 of 49ers' last 5 games
  • The totals have gone OVER in 5 of 49ers' 9 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
49ers		5-124-51-75-80-4
Broncos		12-56-26-38-04-5

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
49ers		10-75-45-37-63-1
Broncos		10-6-14-3-16-35-2-15-4

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
49ers		6-11N/AN/A6-70-4
Broncos		10-7N/AN/A8-02-7

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jan 5th@ARIL 24-47+5.5 LO 43.5ARI +195
Dec 31stDETL 34-40+4 LO 50.5DET +182
Dec 22nd@MIAL 17-29-1.5 LO 44MIA -125
Dec 13thLAL 6-12-3 LU 48.5LA -155
Dec 8thCHIW 38-13-3 WO 43.5SF -163

Broncos vs. 49ers Injury Updates

Broncos Injuries

    49ers Injuries

    • Trevis Gipson
      LB

      Gipson is out with ankle

      Out

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    Team Stats

    Total

    368
    Total Yards
    203
    72
    Total Plays
    53
    5.1
    Yards Per Play
    3.8

    Passing

    222
    YDS
    127
    26/36
    Comps/Atts
    13/27
    5.658
    YPA
    3.567
    3/0
    TDs/INTs
    0/3
    2/7
    Sacks/Yards
    3/20

    Rushing

    153
    Rush Yards
    96
    34
    Attempts
    23
    4.5
    YPC
    4.174
    0
    TDs
    1

    Turnovers

    0
    Fumbles Lost
    1
    0
    Interceptions
    3

    Efficiency

    2/3 66.67%
    Redzone
    1/1 100%
    6/16 0%
    3rd Down
    1/12 0%
    1/2 0%
    4th Down
    1/2 0%

    First Downs

    20
    Total
    11
    12
    Pass
    5
    7
    Rush
    3
    1
    Penalty
    3

    Misc

    11/87
    Penalties/Yards
    9/67
    36:58
    Possession
    23:02

    Broncos vs. 49ers Odds Comparison

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    Broncos at 49ers Team Totals

    MatchupOverUnder
    Broncos
    1-0
    o22.5-115
    u22.5-110
    49ers
    0-1
    o15.5-120
    u15.5-105