Blackhawks vs. Sabres Odds & Betting Predictions - November 22, 2025

Blackhawks at Sabres

12:00 am • ESPN+

Chicago Blackhawks

3

3 - 9

Buffalo Sabres

9

MatchupOpenSpreadTotalMoneyline
Blackhawks 18-18-7	+1.5-170	o6.5-102	+150
Sabres 23-15-4	-1.5+142	u6.5-118	-180

location pin

Saturday 12:00 a.m.

November 22, 2025

KeyBank CenterBuffalo

CHI +135 (1P)

0.5u

R.Dahlin Anytime Goal Scorer Yes+425

0.25u

Blackhawks vs Sabres: Back the 'Dog Tonight
Action Network Staff•
Nov 21, 2025 UTC

See more NHL Coverage

No props found

NHL Public Betting

Sabres are 3-2 in their last 5 games.
Sabres are 3-2 in their last 5 games against the spread
Sabres are 10-12 in their road games against the spread
The totals have gone OVER in 2 of Sabres' last 5 games
The totals have gone OVER in 8 of Sabres' 20 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Sabres	22-20	12-8	10-12	9-9	13-9
Blackhawks	30-13	17-5	13-8	0-2	30-11

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Sabres	19-23	8-12	11-11	10-8	8-14
Blackhawks	19-24	9-13	10-11	0-2	19-22

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Sabres	23-15	N/A	N/A	12-6	11-11
Blackhawks	18-18	N/A	N/A	0-2	18-23

date	opponent	score	spread	over/under	moneyline
Nov 20th	CGY	L 2-6	-1.5 L	O 6.5	CGY -155
Nov 18th	EDM	W 5-1	+1.5 W	U 6.5	BUF +135
Nov 16th	@DET	W 5-4	+1.5 W	O 6.5	BUF +140
Nov 14th	@COL	L 3-6	+1.5 L	O 6.5	COL +320
Nov 13th	@UTA	L 2-5	+1.5 L	O 6.5	UTA +165

Alex Lyon
G
Lyon is out with lower body
Out
Michael Kesselring
D
Kesselring is out with lower body
Out
Justin Danforth
RW
Danforth is out with lower body
Out
Jiri Kulich
C
Kulich is out with ear
Out

Shea Weber
D
Weber is out for season with ankle
Out for Season
Frank Nazar
C
Nazar is out with upper body
Out
Connor Bedard
C
Bedard is day-to-day with shoulder
Day-to-Day

See more NHL Injuries

3

Goals

9

6

Assists

17

2

Penalties

2

23

Shots

30

13

Hits

19

26

Faceoffs Won

33

Could not load odds

See more NHL Odds

MatchupOverUnder
Blackhawks 18-18-7	o2.5-140	u2.5+100
Sabres 23-15-4	o3.5-115	u3.5-125