Devils vs. Panthers Odds & Betting Predictions - November 21, 2025
Devils at Panthers
12:00 am • ESPN+Devils at Panthers Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Devils 39-34-3 | +1.5-200 | o5.5+100 | +125 | |
Panthers 37-37-3 | -1.5+168 | u5.5-115 | -150 | |

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Devils vs. Panthers Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Devils vs. Panthers Public Betting Percentages
Betting Trends
- Panthers are 1-4 in their last 5 games.
- Panthers are 1-4 in their last 5 games against the spread
- Panthers are 13-25 in their road games against the spread
- The totals have gone OVER in 4 of Panthers' last 5 games
- The totals have gone OVER in 20 of Panthers' 39 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Panthers vs. Devils Injury Updates

Panthers Injuries
- Sam ReinhartF
Reinhart is out for season with foot
Out for Season
- Brad MarchandF
Marchand is out with lower body
Out
- Aleksander BarkovC
Barkov is out for season with knee
Out for Season
- Aaron EkbladD
Ekblad is out for season with finger
Out for Season
- Evan RodriguesC
Rodrigues is out for season with finger
Out for Season
- Jonah GadjovichLW
Gadjovich is out for season with upper body
Out for Season
- Niko MikkolaD
Mikkola is out for season with knee
Out for Season
- Anton LundellF
Lundell is out for season with upper body
Out for Season
- Uvis BalinskisD
Balinskis is out for season with foot
Out for Season

Devils Injuries
- Brett PesceD
Pesce is out with lower body
Out
- Zack MacEwenRW
MacEwen is out for season with knee
Out for Season
- Stefan NoesenRW
Noesen is out with knee
Out
- Arseni GritsyukRW
Gritsyuk is out for season with upper body
Out for Season
Team Stats
Devils vs. Panthers Odds Comparison
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Devils at Panthers Team Totals
MatchupOverUnder | ||
|---|---|---|
Devils 39-34-3 | N/A | N/A |
Panthers 37-37-3 | N/A | N/A |

