Sassuolo vs. Inter Odds & Betting Predictions - September 21, 2025

Sassuolo at Inter

6:45 pm

Sassuolo

6-10-5

1

1 - 2

Inter

16-4-1

2

MatchupOpenSpreadTotalMoneyline
Sassuolo 6-10-5	+1.5	+1.5-115	o3.5+125	N/A
Inter 16-4-1	u2.5	-1.5-125	u3.5-163	N/A

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Sunday 6:45 p.m.

September 21, 2025

Giuseppe MeazzaMilan

Serie A Public Betting

Inter are 3-2 in their last 5 games.
Inter are 3-2 in their last 5 games against the spread
Inter are 2-1 in their road games against the spread
The totals have gone OVER in 2 of Inter' last 5 games
The totals have gone OVER in 1 of Inter' 4 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Inter	3-4	1-3	2-1	3-2	0-1
Sassuolo	10-11	3-7	7-4	1-6	9-5

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Inter	3-4	1-3	2-1	1-4	1-0
Sassuolo	9-12	5-5	4-7	4-3	5-9

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Inter	4-3	2-2	2-1	4-1	0-1
Sassuolo	6-10	3-5-2	3-5-3	1-3-3	5-7-2

date	opponent	score	spread	over/under	moneyline
Sep 13th	@JUV	L 3-4	-0.5 L	O 2.5	-
Aug 31st	UDI	L 1-2	-1.5 L	O 2.5	-
Aug 25th	TOR	W 5-0	-1.5 W	O 2.5	INT -275
May 23rd	@COM	W 2-0	-0.5 W	U 3.5	INT -135
May 18th	LAZ	W 2-2	-1 L	O 2.5	LAZ -147

Henrikh Mkhitaryan
MID
Back Injury
Out Indefinitely
Yann Sommer
GK
Ankle Ligaments
Out Indefinitely

Tomas Palacios
DEF
Palacios is doubtful with muscle
Doubtful

Nemanja Matic
MID
Calf/Shin Injury
Out Indefinitely
Armand Lauriente
F
Back Injury
Out
Cristian Volpato
MID
Volpato is out with muscle
Out
Edoardo Pieragnolo
DEF
Pieragnolo is doubtful with muscle
Doubtful
Daniel Boloca
MID
Boloca is doubtful with muscle
Doubtful

See more SERIEA Injuries

Sassuolo

Inter

8

Fouls

13

7

Shots

15

3

Corners

7

3

Offsides

2

0

Red Cards

0

1

Yellow Cards

2

5

Shots On Goal

5

40%

Possession Time

60%

Sassuolo

Goalkeeping

Inter

Could not load odds

See more Serie A Odds

MatchupOverUnder
Sassuolo 6-10-5	o0.5-140	u0.5+105
Inter 16-4-1	o2.5+107	u2.5-152