Buccaneers vs. Panthers Odds & Betting Predictions - December 21, 2025

Buccaneers at Panthers

6:00 pm • FOX
20 - 23

Buccaneers at Panthers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Buccaneers
7-8
-3.5
-3-105
o45-112
-155
Panthers
8-7
u47.5
+3-115
u45-109
+130
location pinSunday 6:00 p.m.
December 21, 2025
Bank of America StadiumCharlotte
Buccaneers vs. Panthers Expert Picks
The Degenerates
The Degenerates
Last 30d: 102-94-4 (-0.5u)
CAR +3 (Live)-110
1u
Jeremiah Rose
Jeremiah Rose
Last 30d: 31-33-1 (-0.3u)
TB -2.5-125
0.5u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 76-93-1 (-6.2u)
Under 45.5-110
1u
Outside divisional game (***) Overall: 266-175-10,60% (ROI:17%) Season:11-12-0,48% (ROI:-9%)
Picks Office
Picks Office
Last 30d: 188-134-1 (+35.1u)
TB -2.5-125
1u
Vegas Refund
Vegas Refund
Last 30d: 33-37-1 (-8.0u)
CAR +3-110
1u
Babs .
Babs .
Last 30d: 106-73-0 (+26.2u)
B.Mayfield u236.5 Pass Yds-115
0.87u
Markus Markets
Markus Markets
Last 30d: 39-30-0 (+3.7u)
M.Evans o4.5 Recs+105
1.05u
NV
Brandon Kravitz
Brandon Kravitz
Last 30d: 75-79-2 (+5.6u)
CAR +3-101
0.5u
Markus Markets
Markus Markets
Last 30d: 39-30-0 (+3.7u)
J.Coker o37.5 Rec Yds-114
0.88u
Brandon Anderson
Brandon Anderson
Last 30d: 53-134-4 (-14.4u)
M.Evans Anytime TD Scorer Yes+185
1.85u
This is a huge game in the NFC South, and the Panthers probably need to sweep these two Bucs games now. It's another spot with big half splits if you like. Carolina is 5-9 ATS in the first half while the Bucs have a winning record, and that flips to the exact opposite after halftime. I don't trust either of these teams, so I'm investing in props instead of a side. Carolina ranks 30th by DVOA against WR1s, and that means it's Mike Evans season. He was back with a vengeance last week, catching six balls for 132 yards on 12 targets. Evans has been a Carolina killer for years. In his last 10 Panthers games, he averages 7.3 catches for 107 yards on 11.3 targets, and he's scored 11 touchdowns in those games with at least one in 7-of-10 and multiple scores three times. Since Week 5, the Panthers have allowed eight touchdowns to the top TD threat at WR in 10 games. Touchdowns are Evans' thing, so I love playing him at +185 (Fanatics) to score a TD, and we have to play two scores at +1300 (DraftKings) too. I like touchdowns better than yards since Evans' snaps are a bit limited but he's always a red zone threat. But I like yards too. Evans has gone over 55.5 yards (FanDuel) in eight of his last 10 healthy games, so I'll hit that too. And in the last 10 Carolina games, those WR1s that score a touchdown also average 93 yards in those games, while Evans is at 89+ yards in eight of his last 10 against the Panthers, so let's go with 90+ yards at +320 (FanDuel) too.
M.Evans 2+ TDs Yes+1300
0.25u
This is a huge game in the NFC South, and the Panthers probably need to sweep these two Bucs games now. It's another spot with big half splits if you like. Carolina is 5-9 ATS in the first half while the Bucs have a winning record, and that flips to the exact opposite after halftime. I don't trust either of these teams, so I'm investing in props instead of a side. Carolina ranks 30th by DVOA against WR1s, and that means it's Mike Evans season. He was back with a vengeance last week, catching six balls for 132 yards on 12 targets. Evans has been a Carolina killer for years. In his last 10 Panthers games, he averages 7.3 catches for 107 yards on 11.3 targets, and he's scored 11 touchdowns in those games with at least one in 7-of-10 and multiple scores three times. Since Week 5, the Panthers have allowed eight touchdowns to the top TD threat at WR in 10 games. Touchdowns are Evans' thing, so I love playing him at +185 (Fanatics) to score a TD, and we have to play two scores at +1300 (DraftKings) too. I like touchdowns better than yards since Evans' snaps are a bit limited but he's always a red zone threat. But I like yards too. Evans has gone over 55.5 yards (FanDuel) in eight of his last 10 healthy games, so I'll hit that too. And in the last 10 Carolina games, those WR1s that score a touchdown also average 93 yards in those games, while Evans is at 89+ yards in eight of his last 10 against the Panthers, so let's go with 90+ yards at +320 (FanDuel) too.
M.Evans o55.5 Rec Yds-114
0.75u
This is a huge game in the NFC South, and the Panthers probably need to sweep these two Bucs games now. It's another spot with big half splits if you like. Carolina is 5-9 ATS in the first half while the Bucs have a winning record, and that flips to the exact opposite after halftime. I don't trust either of these teams, so I'm investing in props instead of a side. Carolina ranks 30th by DVOA against WR1s, and that means it's Mike Evans season. He was back with a vengeance last week, catching six balls for 132 yards on 12 targets. Evans has been a Carolina killer for years. In his last 10 Panthers games, he averages 7.3 catches for 107 yards on 11.3 targets, and he's scored 11 touchdowns in those games with at least one in 7-of-10 and multiple scores three times. Since Week 5, the Panthers have allowed eight touchdowns to the top TD threat at WR in 10 games. Touchdowns are Evans' thing, so I love playing him at +185 (Fanatics) to score a TD, and we have to play two scores at +1300 (DraftKings) too. I like touchdowns better than yards since Evans' snaps are a bit limited but he's always a red zone threat. But I like yards too. Evans has gone over 55.5 yards (FanDuel) in eight of his last 10 healthy games, so I'll hit that too. And in the last 10 Carolina games, those WR1s that score a touchdown also average 93 yards in those games, while Evans is at 89+ yards in eight of his last 10 against the Panthers, so let's go with 90+ yards at +320 (FanDuel) too.
M.Evans 90+ Receiving Yards Yes+320
0.25u
This is a huge game in the NFC South, and the Panthers probably need to sweep these two Bucs games now. It's another spot with big half splits if you like. Carolina is 5-9 ATS in the first half while the Bucs have a winning record, and that flips to the exact opposite after halftime. I don't trust either of these teams, so I'm investing in props instead of a side. Carolina ranks 30th by DVOA against WR1s, and that means it's Mike Evans season. He was back with a vengeance last week, catching six balls for 132 yards on 12 targets. Evans has been a Carolina killer for years. In his last 10 Panthers games, he averages 7.3 catches for 107 yards on 11.3 targets, and he's scored 11 touchdowns in those games with at least one in 7-of-10 and multiple scores three times. Since Week 5, the Panthers have allowed eight touchdowns to the top TD threat at WR in 10 games. Touchdowns are Evans' thing, so I love playing him at +185 (Fanatics) to score a TD, and we have to play two scores at +1300 (DraftKings) too. I like touchdowns better than yards since Evans' snaps are a bit limited but he's always a red zone threat. But I like yards too. Evans has gone over 55.5 yards (FanDuel) in eight of his last 10 healthy games, so I'll hit that too. And in the last 10 Carolina games, those WR1s that score a touchdown also average 93 yards in those games, while Evans is at 89+ yards in eight of his last 10 against the Panthers, so let's go with 90+ yards at +320 (FanDuel) too.
Allan Lem
Allan Lem
Last 30d: 174-135-2 (+5.9u)
B.Irving u16.5 Rush Att-114
0.57u
Tailing @The_Oddsmaker
Sean Koerner
Sean Koerner
Last 30d: 37-34-0 (+0.1u)
B.Irving u16.5 Rush Att-114
0.57u
Somehow cashed on this last week even with TB refusing to give Rachaad White the ball! Projecting closer to 15.4 with around a 60% chance to stay under 16.5
Nick Giffen
Nick Giffen
Last 30d: 41-87-1 (-3.1u)
M.Evans 2+ TDs Yes+1400
0.2u
🪜
M.Evans Anytime TD Scorer Yes+175
1.75u
Mike Evans anytime TD +175 at FanDuel This line is wild to me. Evans has scored at least one touchdown in 21 of 39 games (including playoffs) with Baker Mayfield as his QB. Evans came back from injury with a vengeance last week, posting a 6 catch, 132 yard performance on 12 targets. The Panthers have been a bit stingy against the WR position, but most of that is against the slot where they've allowed just 3 TDs all year to slot-aligned players, but 10 to players lined up out wide. Evans isn't going to drift into the slot all that much, especially with Chris Godwin healthy, so there shouldn't be a strong downgrade on the matchup here. I'd play this down to +135.
Action Pod NFL Picks
Action Pod NFL Picks
Last 30d: 71-154-6 (-19.1u)
M.Evans Anytime TD Scorer Yes+185
1u
M.Evans 2+ TDs Yes+1300
0.1u
M.Evans o55.5 Rec Yds-113
1u
M.Evans 90+ Receiving Yards Yes+320
0.31u
TAN Pod Touchdown Show
TAN Pod Touchdown Show
Last 30d: 41-123-5 (+3.0u)
M.Evans Anytime TD Scorer Yes+165
0.83u
B.Young Anytime TD Scorer Yes+700
0.5u
Grant Neiffer
Grant Neiffer
Last 30d: 44-102-1 (-4.1u)
M.Evans Anytime TD Scorer Yes+185
0.46u
Chris Raybon
Chris Raybon
Last 30d: 19-20-2 (+2.8u)
M.Evans Anytime TD Scorer Yes+190
1.9u
TD in 55% of games w/ Mayfield
Babs .
Babs .
Last 30d: 106-73-0 (+26.2u)
Under 45.5-110
0.91u
Gilles Gallant
Gilles Gallant
Last 30d: 26-71-0 (+2.0u)
M.Evans Anytime TD Scorer Yes+180
1.35u
Evans TD 🪜
M.Evans 2+ TDs Yes+1300
0.25u
Evans TD 🪜
Kenny Ducey
Kenny Ducey
Last 30d: 12-17-1 (-6.7u)
TB -3-108
1.08u
Action Pod NFL Picks
Action Pod NFL Picks
Last 30d: 71-154-6 (-19.1u)
M.Evans Anytime TD Scorer Yes+165
1.01u
Sean Zerillo
Sean Zerillo
Last 30d: 72-62-1 (+5.7u)
Under 45.5-110
0.25u
Brandon Kravitz
Brandon Kravitz
Last 30d: 75-79-2 (+5.6u)
CAR +126
0.63u
Panthers are fiesty underdogs and untrustworthy favorites, been the case all season. I think they’re the better team right now, I’ll happily back them in this race to the top of the NFC South.
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 76-93-1 (-6.2u)
Under 45.5-105
0.48u
Outside divisional game (***) Overall: 263-171-10,61% (ROI:17%) Season:8-8-0,50% (ROI:-

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Buccaneers vs. Panthers Props

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Buccaneers vs. Panthers Public Betting Percentages

Away Logo

Buccaneers

Public

47%

Bets%

53%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Panthers
9-65-24-40-29-4
Buccaneers
5-101-64-43-62-4

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Panthers
7-84-33-50-27-6
Buccaneers
8-76-12-65-43-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Panthers
8-7N/AN/A0-28-5
Buccaneers
7-8N/AN/A5-42-4

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Dec 14th@NOL 17-20-2.5 LU 41.5NO -148
Nov 30thLAW 31-28+10 WO 44.5CAR +422
Nov 25th@SFL 9-20+7.5 LU 49SF +310
Nov 16th@ATLW 30-27+4 WO 42CAR +182
Nov 9thNOL 7-17-5.5 LU 37.5NO -245

Buccaneers vs. Panthers Injury Updates

Buccaneers Injuries

  • Ko Kieft
    TE

    Kieft is out with leg

    Out

  • Benjamin Morrison
    CB

    Morrison is out with quad

    Out

Panthers Injuries

  • David Moore
    WR

    Moore is out with elbow

    Out

  • Damarri Mathis
    CB

    Mathis is out with knee

    Out

Team Stats
296
Total Yards
275
61
Total Plays
54
4.9
Yards Per Play
5.1
145
YDS
191
18/26
Comps/Atts
21/32
4.536
YPA
5.118
1/1
TDs/INTs
2/0
2/18
Sacks/Yards
2/17
169
Rush Yards
101
33
Attempts
20
5.121
YPC
5.05
1
TDs
0
0
Fumbles Lost
0
1
Interceptions
0
2/3 66.67%
Redzone
1/2 50%
8/14 0%
3rd Down
6/12 0%
0/0 0%
4th Down
0/0 0%
20
Total
16
9
Pass
9
8
Rush
7
3
Penalty
0
8/56
Penalties/Yards
5/30
34:36
Possession
25:24

Buccaneers vs. Panthers Odds Comparison

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Buccaneers at Panthers Team Totals

MatchupOverUnder
Buccaneers
7-8
o23.5-120
u23.5-110
Panthers
8-7
o21.5-105
u21.5-120