Orioles vs. Guardians Odds & Betting Predictions - July 22, 2025

Orioles at Guardians

10:40 pm • CLEG

Baltimore Orioles

3-5

3 - 6

Cleveland Guardians

5-3

pitcher		team	era	w-l
J.Cantillo			3.21	5-3
B.Young			6.24	1-7

MatchupOpenSpreadTotalMoneyline
Orioles 3-5	+1.5	+1.5-162	o8-108	+135
Guardians 5-3	u8	-1.5+134	u8-111	-161

Tuesday 10:40 p.m.

July 22, 2025

Progressive FieldCleveland

S.Kwan o1.5 Hits + Runs + RBIs-130

CLE -152

0.33u

Under 8-104

1.04u

Flat Favorites at Home (***) Overall: 503-346-38,59% (ROI:15%) Season:10-8-1,56% (ROI:5%) Blowing In Ballparks (***) Overall: 865-541-72,62% (ROI:18%) Season:35-21-1,63% (ROI:19%)

A.Martinez o1.5 Hits + Runs + RBIs-120

$1.00

B.Young u3.5 Ks+124

0.62u

J.Cantillo u6.5 Ks-140

0.5u

Under 8.5-115

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J.Cantillo u6.5 Ks-135

0.5u

Under 8.5-117

0.59u

BAL +125

CLE -135

CLE -145 (F5)

0.5u

Young 4.31 SIERA/4.65 xERA (LHBs .463 wOBA, .369 xwOBA - CLE can go 9 LHBs), Cantillo struck out 18 of 58 in three starts (all road, 14.9 SwStr%) - BAL 84/76 Rd/v LHP wRC+, CLE far better defense, slightly better pen estimators L30 days and even slightly better base running.

CLE -132

0.5u

See notes on F5

Orioles vs. Guardians: 2 Strikeout Props for Tuesday
Collin Whitchurch•
Jul 22, 2025 UTC
3 MLB Player Props for Tuesday
Alex Hinton•
Jul 22, 2025 UTC

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No props found

MLB Public Betting

Guardians are 3-2 in their last 5 games.
Guardians are 3-2 in their last 5 games against the spread
Guardians are 4-3 in their road games against the spread
The totals have gone OVER in 1 of Guardians' last 5 games
The totals have gone OVER in 0 of Guardians' 1 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Guardians	5-3	1-0	4-3	1-0	4-3
Orioles	2-6	2-4	0-2	2-4	0-2

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Guardians	3-5	0-1	3-4	0-1	3-4
Orioles	4-4	3-3	1-1	3-3	1-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Guardians	5-3	1-0	4-3	1-0	4-3
Orioles	3-5	3-3	0-2	3-3	0-2

date	opponent	score	spread	over/under	moneyline
Jul 21st	BAL	W 10-5	-1.5 W	O 8.5	CLE -143
Jul 20th	ATH	W 8-2	+1.5 W	O 7.5	CLE -106
Jul 19th	ATH	L 2-8	-1.5 L	O 9	ATH -134
Jul 18th	ATH	W 8-6	-1.5 W	O 8	CLE -134
Jul 13th	@CWS	W 6-5	-1.5 L	O 8.5	CLE -142

Heston Kjerstad
LF
Kjerstad is out with hamstring
Out
Jordan Westburg
3B
Westburg is out with elbow
Out
Jackson Holliday
2B
Holliday is out with hand
Out

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PITCHER	PC	IP	K	ER
RB.Young, P	73	4.1	3	3
RA.Kittredge, P	6	0.2	1	0
LG.Soto, P	33	1	2	2
RY.Cano, P	17	1	0	1
RS.Dominguez, P	14	1	0	0

HITTERS	H-AB	R	HR	RBI
1J.Holliday, 2B	1-4	0	0	1
2J.Westburg, DH	0-4	0	0	0
3G.Henderson, SS	0-2	0	0	0
4R.Laureano, RF	1-4	1	1	1
5C.Mullins, CF	0-4	0	0	0
6R.Urias, 3B	2-4	1	0	0
7C.Cowser, LF	1-4	0	0	0
8C.Mayo, 1B	1-1	1	0	0
9J.Stallings, C	0-2	0	0	0
9R.O'Hearn, PH	1-1	0	0	0
9A.Jackson, C	0-1	0	0	0

PITCHER	PC	IP	K	ER
LJ.Cantillo, P	95	5	5	1
LE.Sabrowski, P	23	1.2	2	1
RM.Festa, P	8	0	0	1
RC.Smith, P	31	1.1	1	0
RE.Clase, P	13	1	1	0

HITTERS	H-AB	R	HR	RBI
1S.Kwan, LF	0-5	0	0	0
2A.Martinez, CF	3-5	1	0	1
3J.Ramirez, 3B	1-2	1	1	1
4K.Manzardo, DH	1-3	0	0	2
5C.Santana, 1B	0-4	0	0	0
6N.Jones, RF	0-3	1	0	0
7D.Schneemann, 2B	1-2	1	0	0
8B.Rocchio, SS	1-3	1	0	2
9B.Naylor, C	0-2	1	0	0