Orioles vs. Red Sox Odds & Betting Predictions - July 22, 2026

Orioles at Red Sox

11:10 pm • MASN
@
Starting Pitchers
pitcherteameraw-l
Kyle Bradish logoK.BradishBaltimore Orioles logo3.616-9

Orioles at Red Sox Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Orioles
49-52
+1.5
+1.5-178
o8.5-131
+115
Red Sox
51-48
u8.5
-1.5+147
u8.5+101
-136
location pinWednesday 11:10 p.m.
July 22, 2026
Fenway ParkBoston
thermometer image77°Fahrenheit
rain image30%Rain
wind image6Wind
Orioles vs. Red Sox Expert Picks
Frank Ammirante
Frank Ammirante
Last 30d: 331-373-6 (-39.0u)
Under 8.5+100
1u
Under 4.5 (F5)-110
1.1u

Orioles vs. Red Sox Previews & Analysis

  • 3 Late-Slate, Sharp-Action Picks article feature image

    3 Late-Slate, Sharp-Action Picks

    Alex Kolodziej
    Jul 22, 2026 UTC
  • Derek Carty's 4 MLB Player Props for Wednesday article feature image

    Derek Carty's 4 MLB Player Props for Wednesday

    Action Network Staff
    Jul 22, 2026 UTC
  • Opening Pitch: Zerillo's MLB Projections for Wednesday via BARTOLO article feature image

    Opening Pitch: Zerillo's MLB Projections for Wednesday via BARTOLO

    Sean Zerillo
    Jul 21, 2026 UTC
See more MLB Coverage Right Arrow

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

Orioles vs. Red Sox Public Betting Percentages

Away Logo

Orioles

Public

14%

Bets%

86%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Red Sox
47-5221-2826-2428-3518-17
Orioles
50-5127-2623-2523-2826-23

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Red Sox
45-50-420-26-325-24-130-30-315-19-1
Orioles
53-45-327-24-226-21-124-25-229-19-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Red Sox
51-4822-2729-2132-3118-17
Orioles
49-5228-2521-2726-2522-27

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jul 20thBALW 6-5-1.5 LO 8.5BOS -166
Jul 19thTBW 6-1-1.5 WU 8.5BOS -125
Jul 18thTBW 7-6+1.5 WO 9.5BOS -119
Jul 17thTBW 5-3-1.5 WU 9BOS -131
Jul 17thTBW 10-0+1.5 WO 8.5BOS -118

Orioles vs. Red Sox Injury Updates

Orioles Injuries

  • Heston Kjerstad
    LF

    Kjerstad is out with hamstring

    Out

  • Jordan Westburg
    3B

    Westburg is out with elbow

    Out

Red Sox Injuries

  • Tanner Houck
    SP

    Houck is out with arm

    Out

  • Triston Casas
    1B

    Casas is out with knee

    Out

  • Kutter Crawford
    SP

    Crawford is out with wrist

    Out

Orioles vs. Red Sox Starting Lineups
Orioles Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Kyle Bradish logoRK.Bradish, P6-93.611.3518.89
HITTERSAVGOBPSLGHR
Taylor Ward logo1T.Ward, LF.251.386.3617
Pete Alonso logo2P.Alonso, 1B.246.347.46021
Gunnar Henderson logo3G.Henderson, SS.224.293.40217
Tyler O'Neill logo4T.O'Neill, RF.205.297.3606
Coby Mayo logo5C.Mayo, DH.196.264.40013
Leody Taveras logo6L.Taveras, CF.240.320.3634
Jeremiah Jackson logo7J.Jackson, 2B.252.271.4007
Christian Encarnacion-Strand logo8C.Encarnacion-Strand, 3B.375.375.7501
Chadwick Tromp logo9C.Tromp, C.667.667.6670
Red Sox Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Ranger Suarez logoLR.Suarez, P4-33.151.1619.56
HITTERSAVGOBPSLGHR
Anthony Seigler logo1A.Seigler, 2B.244.317.3892
Ceddanne Rafaela logo2C.Rafaela, CF.281.326.4338
Wilyer Abreu logo3W.Abreu, RF.267.339.46115
Willson Contreras logo4W.Contreras, 1B.289.384.55722
Masataka Yoshida logo5M.Yoshida, DH.267.341.3984
Caleb Durbin logo6C.Durbin, 3B.236.299.40010
Jarren Duran logo7J.Duran, LF.191.254.34013
Carlos Narvaez logo8C.Narvaez, C.200.266.2943
Tsung-Che Cheng logo9T.Cheng, SS.278.341.3060

Orioles vs. Red Sox Odds Comparison

Right Arrow

Could not load odds

Orioles at Red Sox Team Totals

MatchupOverUnder
Orioles
49-52
N/A
N/A
Red Sox
51-48
N/A
N/A