Padres vs. Giants Odds & Betting Predictions - May 6, 2026

Padres at Giants

1:45 am • NBCS-BA

San Diego Padres

@

San Francisco Giants

pitcher		team	era	w-l
L.Webb			4.30	2-3
W.Buehler			5.40	1-2

MatchupOpenSpreadTotalMoneyline
Padres 20-14	+1.5	+1.5-192	o7.5-103	+110
Giants 14-21	u7.5	-1.5+159	u7.5-118	-130

location pin

Wednesday 1:45 a.m.

May 06, 2026

Oracle ParkSan Francisco

thermometer image

59°Fahrenheit

rain image

0%Rain

wind image

10Wind

Under 7.5-115

0.5u

@Zerillo ⭐️⭐️ https://myaction.app/JSRRLRwFT2b

W.Buehler o3.5 Ks-110

0.55u

Under 7.5-115

0.58u

Bet to -125 or 7 (-102)

Our 5 MLB Best Bets for Tuesday
Action Network Staff•
May 5, 2026 UTC
Padres vs Giants: Pitching Gap Creates Dog Value
Kevork Mahserejian•
May 5, 2026 UTC
Adam Trigger's Triple-A Picks For Tuesday
Adam Trigger•
May 5, 2026 UTC

See more MLB Coverage

No props found

MLB Public Betting

Giants are 1-4 in their last 5 games.
Giants are 3-2 in their last 5 games against the spread
Giants are 7-11 in their road games against the spread
The totals have gone OVER in 1 of Giants' last 5 games
The totals have gone OVER in 7 of Giants' 17 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Giants	15-20	8-9	7-11	4-7	11-13
Padres	19-15	12-7	7-8	12-9	7-6

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Giants	14-19-2	7-9-1	7-10-1	8-3	6-16-2
Padres	15-18-1	10-8-1	5-10	9-11-1	6-7

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Giants	14-21	8-9	6-12	5-6	9-15
Padres	20-14	11-8	9-6	13-8	7-6

date	opponent	score	spread	over/under	moneyline
May 5th	SD	W 3-2	+1.5 W	U 8	SF +112
May 3rd	@TB	L 1-2	+1.5 W	U 8	TB +104
May 2nd	@TB	L 1-5	-1.5 L	U 7.5	TB -115
May 1st	@TB	L 0-3	+1.5 L	U 7.5	TB +117
Apr 30th	@PHI	L 5-6	+1.5 W	O 8.5	PHI +119

Hayden Birdsong
SP
Birdsong is out with arm
Out

Joe Musgrove
SP
Musgrove is out with elbow
Out
Will Wagner
3B
Wagner is out with oblique
Out

See more MLB Injuries

PITCHER		W-L	ERA	WHIP	K/9
RW.Buehler, P		1-2	5.40	1.560	8.64

HITTERS	AVG	OBP	SLG	HR
1R.Laureano, LF	.238	.301	.426	5
2F.Tatis, RF	.252	.324	.301	0
3J.Merrill, CF	.220	.283	.362	4
4M.Machado, 3B	.221	.328	.389	5
5X.Bogaerts, SS	.262	.343	.402	5
6G.Sheets, 1B	.215	.263	.441	4
7M.Andujar, DH	.305	.337	.476	2
8L.Campusano, C	.300	.352	.620	3
9J.Cronenworth, 2B	.144	.272	.196	1

PITCHER		W-L	ERA	WHIP	K/9
RL.Webb, P		2-3	4.29	1.364	7.77

HITTERS	AVG	OBP	SLG	HR
1J.Lee, RF	.272	.321	.400	2
2C.Schmitt, 3B	.308	.359	.542	5
3L.Arraez, 2B	.316	.340	.398	0
4H.Ramos, LF	.270	.306	.421	3
5R.Devers, 1B	.218	.264	.308	2
6W.Adames, SS	.197	.236	.343	3
7B.Eldridge, DH	.000	.333	.000	0
8P.Bailey, C	.152	.221	.190	1
9D.Gilbert, CF	.255	.296	.392	2

Could not load odds

See more MLB Odds

MatchupOverUnder
Padres 20-14	N/A	N/A
Giants 14-21	N/A	N/A