Pirates vs. Reds Odds & Betting Predictions - September 24, 2025
Pirates at Reds
10:40 pm • SportsNet PTStarting Pitchers
pitcher | team | era | w-l | |
---|---|---|---|---|
![]() | ![]() | 2.76 | 7-4 | |
![]() | ![]() | 1.97 | 10-10 |
Pirates at Reds Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Pirates 71-91 | -1.5 | PK-109 | o7-103 | +108 |
![]() Reds 83-79 | u7 | PK-109 | u7-114 | -102 |

Great American Ball ParkCincinnati
Pirates vs. Reds Expert Picks

Gamblers Dream
Last 30d: 4-5-0 (+10.9u)
CIN +100 (Live)
1u

Firefighter Bets
Last 30d: 136-130-1 (-3.2u)
CIN -125
1u

The Pick Don
Last 30d: 26-19-0 (+3.8u)
Under 3.5 (F5)-135
1.5u
It doesn’t get much simpler than this when two of my favorite pitchers are facing off. Let’s start with Paul Skenes, who needs no introduction. He’s elite and well on his way to winning the NL Cy Young. Skenes owns a 2.03 ERA and has been far and away the most dominant pitcher since his 2024 debut. He ranks in the 99th percentile in run value and carries one of the best expected batting averages in the league. Meanwhile, the Reds offense has been lifeless all season. Over the past month, they rank just 26th in batting average along with a 88 wRC+. This is not a good lineup, and with the pressure of a playoff push, nerves at the plate will only add to their struggles. Cincinnati has scored just three runs across its last two games. When Skenes faced them in August, he allowed no runs and struck out eight across six innings.
On the other side, since returning from injury, Hunter Greene has been outstanding. He’s fresh off a complete game shutout against the Cubs, allowing just one hit over nine innings. That was his second start in three outings where he gave up only a single hit. Greene is striking out batters at a 31.5% clip with a 32.1% chase rate, and his fastball remains one of the best in baseball. Now, he draws the worst road offense in the league (Rockies don’t count). The Pirates are hitting just .215 with a brutal 74 wRC+ away from PNC Park. These are also two very good defensive teams, so hopefully we don’t screwed by errors like last night’s under. I’m also going to avoid the bullpens and stick with the F5 under. I wouldn’t be surprised if this game is 0-0 or 1-0 after five innings. I’m taking this at U3.5 (-135) on Draft Kings, but would take it down to 3 as well.

💰🦡 Jake
Last 30d: 99-125-6 (+25.6u)
CIN -0.5 (F5)+135
1u

Charlie Wright
Last 30d: 15-12-0 (+1.8u)
Under 3.5 (F5)-135
1u
Hunter Greene is coming off a complete game shutout against the Cubs. He allowed just 3 baserunners. Greene has now allowed 2 ERs in 4 home starts since returning from the IL. He draws a Pittsburgh offense that ranks dead last in OPS and wOBA vs. RHP in September.
On the other side, it’s Paul Skenes. What else is there to say? He can put the finishing touches on his Cy Young campaign tonight. Cincinnati is in the thick of the NL Wild Card race, but not because of their bats. The Reds are 23rd in wRC+ vs. righties this month.

Lines at Lunch
Last 30d: 92-92-3 (-6.6u)
Under 7-118
1.18u
Prop Odds Comparison
Line Movement Tracker
Pirates vs. Reds Public Betting Percentages
Betting Trends
- Reds are 3-2 in their last 5 games.
- Reds are 2-3 in their last 5 games against the spread
- Reds are 42-39 in their road games against the spread
- The totals have gone OVER in 1 of Reds' last 5 games
- The totals have gone OVER in 26 of Reds' 79 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Pirates vs. Reds Injury Updates

Pirates Injuries
- Johan OviedoSP
Oviedo is questionable with elbow
Questionable
- Endy Rodriguez1B
Rodriguez is out with elbow
Out
- Jared JonesSP
Jones is out with elbow
Out

Reds Injuries
- Noelvi Marte3B
Marte is day-to-day with side
Day-to-Day
- Reiver SanmartinRP
Sanmartin is out with elbow
Out
- Brandon WilliamsonSP
Williamson is out for season with elbow
Out for Season
- Douglas AshcraftRP
Ashcraft is out with groin
Out
- Chase BurnsSP
Burns is out with hip
Out
- Julian AguiarSP
Aguiar is out for season with elbow
Out for Season
- Rhett LowderSP
Lowder is out with elbow
Out
- William SpiersRP
Spiers is out with shoulder
Out
Pirates vs. Reds Box Score

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 85 | 6 | 7 | 0 | |
![]() | 24 | 1 | 2 | 0 | |
![]() | 16 | 0.2 | 0 | 1 | |
![]() | 21 | 1.1 | 2 | 1 | |
![]() | 18 | 0.2 | 1 | 0 | |
![]() | 37 | 1.1 | 2 | 0 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-1 | 0 | 0 | 1 |
![]() | 0-5 | 0 | 0 | 0 |
![]() | 1-3 | 3 | 0 | 0 |
![]() | 3-5 | 0 | 0 | 3 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 1-5 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-4 | 1 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 96 | 6 | 7 | 2 | |
![]() | 30 | 2 | 3 | 0 | |
![]() | 26 | 1 | 1 | 0 | |
![]() | 17 | 1 | 1 | 0 | |
![]() | 12 | 1 | 0 | 0 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 1-5 | 1 | 0 | 0 |
![]() | 2-6 | 1 | 1 | 1 |
![]() | 0-3 | 0 | 0 | 1 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-5 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 4-5 | 1 | 1 | 1 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-5 | 0 | 0 | 0 |
Pirates vs. Reds Odds Comparison
Could not load odds
Pirates at Reds Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Pirates 71-91 | o3.5+105 | u3.5-135 |
![]() Reds 83-79 | o3.5-103 | u3.5-125 |