Louisville vs. Indiana Odds & Betting Predictions - December 6, 2025
Louisville at Indiana
7:15 pm • CBSLouisville at Indiana Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Louisville 17-6 | -3.5-110 | o162-110 | -180 | |
Indiana 16-8 | +3.5-110 | u162-110 | +150 | |

Gainbridge FieldhouseIndianapolis
Louisville vs. Indiana Expert Picks
Mike McNamara
Last 30d: 57-91-1 (-6.2u)
IND +3.5-110
0.28u
Player Prop Savant
Last 30d: 48-50-1 (-3.1u)
Over 160.5-105
1u
Ryan Minion
Last 30d: 226-259-4 (+28.6u)
M.Brown o17.5 Pts-130
$1.30
Tickle the Twine
Last 30d: 55-48-1 (+1.3u)
Under 162-110
1u
Ryan Minion
Last 30d: 226-259-4 (+28.6u)
LOU -2.5 (1H)-110
$1.00
LOU -4.5-110
$3.00
Louisville vs. Indiana Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Louisville vs. Indiana Public Betting Percentages
Betting Trends
- Indiana are 4-1 in their last 5 games.
- Indiana are 3-2 in their last 5 games against the spread
- Indiana are 5-4 in their road games against the spread
- The totals have gone OVER in 2 of Indiana' last 5 games
- The totals have gone OVER in 7 of Indiana' 15 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 12-12 | 7-8 | 5-4 | 9-7 | 3-3 | |
| 11-12 | 7-7 | 4-5 | 8-7 | 0-3 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 11-13 | 7-8 | 4-5 | 9-7 | 2-4 | |
| 8-15 | 4-10 | 4-5 | 6-9 | 0-3 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 16-8 | N/A | N/A | 12-4 | 2-4 | |
| 17-6 | N/A | N/A | 12-3 | 0-3 |
Last 5 Matchups
Louisville vs. Indiana Injury Updates

Louisville Injuries
- Spencer LeggG
Legg is questionable with ankle
Questionable

Indiana Injuries
- Jason DrakeG
Drake is out with foot
Out
- Jordan RayfordG
Rayford is out for season with undisclosed
Out for Season
- Tayton ConerwayG
Conerway is questionable with illness
Questionable
Team Stats
25-54 (46%)
Field Goals
26-63 (41%)
24-28 (86%)
Free Throws
15-19 (79%)
13-31 (42%)
3P
11-34 (32%)
34
Rebounds
27
15
Assists
14
13
Turnovers
12
9
Steals
4
5
Blocks
1
19
Fouls
21
Louisville vs. Indiana Odds Comparison
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Louisville at Indiana Team Totals
MatchupOverUnder | ||
|---|---|---|
Louisville 17-6 | N/A | N/A |
Indiana 16-8 | N/A | N/A |



