Louisville vs. Indiana Odds & Betting Predictions - December 6, 2025

Louisville at Indiana

7:15 pm • CBS
87 - 78

Louisville at Indiana Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Louisville
17-6
-3.5-110
o162-110
-180
Indiana
16-8
+3.5-110
u162-110
+150
location pinSaturday 7:15 p.m.
December 06, 2025
Gainbridge FieldhouseIndianapolis
Louisville vs. Indiana Expert Picks
Mike McNamara
Mike McNamara
Last 30d: 57-91-1 (-6.2u)
IND +3.5-110
0.28u
Player Prop Savant
Player Prop Savant
Last 30d: 48-50-1 (-3.1u)
Over 160.5-105
1u
Ryan Minion
Ryan Minion
Last 30d: 226-259-4 (+28.6u)
M.Brown o17.5 Pts-130
$1.30
Tickle the Twine
Tickle the Twine
Last 30d: 55-48-1 (+1.3u)
Under 162-110
1u
Ryan Minion
Ryan Minion
Last 30d: 226-259-4 (+28.6u)
LOU -2.5 (1H)-110
$1.00
LOU -4.5-110
$3.00

Louisville vs. Indiana Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Louisville vs. Indiana Public Betting Percentages

Away Logo

Louisville

Public

58%

Bets%

42%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Indiana
12-127-85-49-73-3
Louisville
11-127-74-58-70-3

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Indiana
11-137-84-59-72-4
Louisville
8-154-104-56-90-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Indiana
16-8N/AN/A12-42-4
Louisville
17-6N/AN/A12-30-3

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Dec 4th@MINNL 64-73-8.5 LU 144.5MINN -463
Nov 29thCOOKW 100-56-29.5 WO 149.5IND -20000
Nov 26thKSUW 86-69-10.5 WU 164.5IND -562
Nov 20thLINWW 73-53-33 LU 155.5-
Nov 16thIWW 69-61-28.5 LU 157.5-

Louisville vs. Indiana Injury Updates

Louisville Injuries

  • Spencer Legg
    G

    Legg is questionable with ankle

    Questionable

Indiana Injuries

  • Jason Drake
    G

    Drake is out with foot

    Out

  • Jordan Rayford
    G

    Rayford is out for season with undisclosed

    Out for Season

  • Tayton Conerway
    G

    Conerway is questionable with illness

    Questionable

Team Stats
25-54 (46%)
Field Goals
26-63 (41%)
24-28 (86%)
Free Throws
15-19 (79%)
13-31 (42%)
3P
11-34 (32%)
34
Rebounds
27
15
Assists
14
13
Turnovers
12
9
Steals
4
5
Blocks
1
19
Fouls
21

Louisville vs. Indiana Odds Comparison

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Louisville at Indiana Team Totals

MatchupOverUnder
Louisville
17-6
N/A
N/A
Indiana
16-8
N/A
N/A