Chargers vs. Rams Odds & Betting Predictions - December 22, 2025
Chargers at Rams
4:00 pm • ESPN+Chargers at Rams Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Chargers 14-17 | +11.5 | +13.5-105 | o127-115 | +750 |
Rams 17-15 | u128.5 | -13.5-115 | u127-105 | -1200 |

Rose Hill GymnasiumBronx
Chargers vs. Rams Expert Picks
Chargers vs. Rams Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Chargers vs. Rams Public Betting Percentages
Betting Trends
- Rams are 2-3 in their last 5 games.
- Rams are 3-2 in their last 5 games against the spread
- Rams are 6-4 in their road games against the spread
- The totals have gone OVER in 2 of Rams' last 5 games
- The totals have gone OVER in 3 of Rams' 19 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Rams vs. Chargers Injury Updates

Rams Injuries
- Ryan PettisG
Pettis is out with undisclosed
Out
- Jack WhitbournC
Whitbourn is questionable with undisclosed
Questionable

Chargers Injuries
Team Stats
Chargers vs. Rams Odds Comparison
Could not load odds
Chargers at Rams Team Totals
MatchupOverUnder | ||
|---|---|---|
Chargers 14-17 | N/A | N/A |
Rams 17-15 | N/A | N/A |


