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USC vs. Notre Dame Odds & Betting Predictions - October 18, 2025

USC at Notre Dame

11:30 pm • NBC

USC Trojans

0-0
24
24 - 34

Notre Dame Fighting Irish

0-0
34

USC at Notre Dame Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
USC
0-0
+10.5
+10.5-110
o60.5-105
+300
Notre Dame
0-0
u53.5
-10.5-110
u60.5-112
-370
location pinSaturday 11:30 p.m.
October 18, 2025
Notre Dame StadiumSouth Bend
USC vs. Notre Dame Expert Picks
Mike McNamara
Mike McNamara
Last 30d: 54-76-6 (-0.5u)
ND -200 (Live)
0.2u
Scott Rickenbach
Scott Rickenbach
Last 30d: 62-57-2 (-1.9u)
USC +10.5-115
0.87u
YBK Picks.com
Last 30d: 10-15-0 (-10.3u)
ND -10.5-105
2u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 0-0-0 (+0.0u)
Over 59.5-110
1u
Vegas Refund
Vegas Refund
Last 30d: 15-7-0 (+7.3u)
ND -10-110
1.1u
Kevin Thomas
Kevin Thomas
Last 30d: 8-7-0 (+0.8u)
USC +10.5-115
0.87u
Doug Ziefel
Doug Ziefel
Last 30d: 112-116-11 (+12.1u)
K.Miller Anytime TD Scorer Yes+136
0.37u
Collin Whitchurch
Collin Whitchurch
Last 30d: 11-22-1 (-0.7u)
ND o34.5 Team Total+111
0.25u
Ryan Minion
Ryan Minion
Last 30d: 210-289-17 (-67.0u)
ND o35 Team Total-110
$1.10
Big Bets On Campus (CFB)
Big Bets On Campus (CFB)
Last 30d: 0-0-0 (+0.0u)
J.Price o70.5 Rush Yds-115
1u
@_Collin1 https://podcasts.apple.com/us/podcast/college-football-week-8-betting-preview/id1579379256?i=1000732214184
ND o35 Team Total-109
1u
@_Collin1 https://podcasts.apple.com/us/podcast/college-football-week-8-betting-preview/id1579379256?i=1000732214184
Sandy Plashkes
Sandy Plashkes
Last 30d: 75-86-0 (+11.6u)
ND -9.5-110
2u
Mjaybrod
Mjaybrod
Last 30d: 23-16-0 (+5.3u)
ND -9.5-110
0.91u
TheDegenerateWeekly -9.5
Ryan Minion
Ryan Minion
Last 30d: 210-289-17 (-67.0u)
J.Love o90.5 Rush Yds-120
$1.00
Doug Ziefel
Doug Ziefel
Last 30d: 112-116-11 (+12.1u)
USC +3.5 (1Q)-120
0.5u
Collin Wilson
Collin Wilson
Last 30d: 0-0-0 (+0.0u)
J.Price o61.5 Rush Yds-114
0.5u
Full writeup Action Network. Zone read efficiency poor for USC defense. Price best inside/outside rusher in Irish backfield by yards per carry. Averaging 70.3 rushing yards per game
ND o35.5 Team Total-105
1.05u
Full Writeup coming Action Network. Side is inflated w USC injuries on offense. Notre Dame extreme advantages in run concepts. Heavy rain expected early making a sloppy track
Doug Ziefel
Doug Ziefel
Last 30d: 112-116-11 (+12.1u)
Under 62.5-115
0.5u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 0-0-0 (+0.0u)
ND -7.5-110
0.91u

USC vs. Notre Dame Previews & Analysis

  • 2 Model Projection Plays Tonight article feature image

    2 Model Projection Plays Tonight

    Alex Kolodziej•
    Oct 18, 2025 UTC
  • USC vs. Notre Dame: 2 Bets for Saturday Night article feature image

    USC vs. Notre Dame: 2 Bets for Saturday Night

    Collin Wilson•
    Oct 18, 2025 UTC
  • Our +285 Parlay for USC vs. Notre Dame article feature image

    Our +285 Parlay for USC vs. Notre Dame

    Alex Hinton•
    Oct 18, 2025 UTC
  • Wilson's Week 8 NCAAF Betting Card article feature image

    Wilson's Week 8 NCAAF Betting Card

    Collin Wilson•
    Oct 18, 2025 UTC
See more NCAAF Coverage Right Arrow

Prop Odds Comparison

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No props found

Line Movement Tracker

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USC vs. Notre Dame Public Betting Percentages

Away Logo

USC

Public

Home Logo

Notre Dame

58%

Bets%

42%

Money%

NCAAF Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Notre Dame		N/AN/AN/AN/AN/A
USC		N/AN/AN/AN/AN/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Notre Dame		N/AN/AN/AN/AN/A
USC		N/AN/AN/AN/AN/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Notre Dame		N/AN/AN/AN/AN/A
USC		N/AN/AN/AN/AN/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 11thNCSTW 36-7-23.5 WU 59.5ND -2400
Oct 4thBOISEW 28-7-21.5 LU 63ND -1600
Sep 27th@ARKW 56-13-5.5 WO 63.5ND -218
Sep 20thPURW 56-30-24.5 WO 51ND -4000
Sep 13thTA&ML 40-41-6.5 LO 49.5TA&M -250
Team Stats

Total

361
Total Yards
407
58
Total Plays
57
6.224137931034483
Yards Per Play
7.140350877192983

Passing

302
YDS
136
19/33
Comps/Atts
16/25
9.151515151515152
YPA
5.44
2/1
TDs/INTs
1/1
1/2
Sacks/Yards
1/9

Rushing

59
Rush Yards
271
25
Attempts
32
2.36
YPC
8.46875
0
TDs
2

Turnovers

1
Fumbles Lost
0
1
Interceptions
1

Efficiency

2/3 66.67%
Redzone
3/5 60%
4/10 0%
3rd Down
2/9 0%
0/1 0%
4th Down
1/1 0%

First Downs

21
Total
20
12
Pass
6
3
Rush
14
6
Penalty
0

Misc

1/5
Penalties/Yards
8/96

USC vs. Notre Dame Odds Comparison

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See more NCAAF Odds Right Arrow

USC at Notre Dame Team Totals

MatchupOverUnder
USC
0-0
N/A
N/A
Notre Dame
0-0
N/A
N/A