USC vs. Notre Dame Odds & Betting Predictions - October 18, 2025
USC at Notre Dame
11:30 pm • NBCUSC at Notre Dame Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 USC 6-2 | +10.5 | +10.5-110 | o60.5-105 | +300 |
 Notre Dame 6-2 | u53.5 | -10.5-110 | u60.5-112 | -370 |
Notre Dame StadiumSouth Bend
USC vs. Notre Dame Expert Picks
Scott Rickenbach
Last 30d: 117-101-1 (+2.7u)
USC +10.5-115
0.87u
YBK Picks.com
Last 30d: 59-41-1 (+32.5u)
ND -10.5-105
2u
Top Shelf Action 🥃
Last 30d: 195-177-2 (-0.5u)
Over 59.5-110
1u
Vegas Refund
Last 30d: 38-38-1 (-3.8u)
ND -10-110
1.1u
Kevin Thomas
Last 30d: 4-7-1 (-3.4u)
USC +10.5-115
0.87u
Big Bets On Campus (CFB)
Last 30d: 38-38-2 (-1.7u)
ND o35 Team Total-109
1u
J.Price o70.5 Rush Yds-115
1u
Sandy Plashkes
Last 30d: 104-116-1 (-8.6u)
ND -9.5-110
2u
Mjaybrod
Last 30d: 103-102-0 (+10.4u)
ND -9.5-110
0.91u
TheDegenerateWeekly -9.5
Collin Wilson
Last 30d: 83-63-0 (+18.4u)
J.Price o61.5 Rush Yds-114
0.5u
Full writeup Action Network. Zone read efficiency poor for USC defense. Price best inside/outside rusher in Irish backfield by yards per carry. Averaging 70.3 rushing yards per game
ND o35.5 Team Total-105
1.05u
Full Writeup coming Action Network. Side is inflated w USC injuries on offense. Notre Dame extreme advantages in run concepts. Heavy rain expected early making a sloppy track
Top Shelf Action 🥃
Last 30d: 195-177-2 (-0.5u)
ND -7.5-110
0.91u
USC vs. Notre Dame Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
USC vs. Notre Dame Public Betting Percentages
Betting Trends
- Notre Dame are 4-1 in their last 5 games.
- Notre Dame are 3-2 in their last 5 games against the spread
- Notre Dame are 1-2 in their road games against the spread
- The totals have gone OVER in 3 of Notre Dame' last 5 games
- The totals have gone OVER in 2 of Notre Dame' 5 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 3-5 | 2-3 | 1-2 | 3-5 | N/A |
| 4-4 | 3-1 | 1-3 | 3-4 | 1-0 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 4-4 | 2-3 | 2-1 | 4-4 | N/A |
| 4-4 | 3-1 | 1-3 | 4-3 | 0-1 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 6-2 | N/A | N/A | 6-2 | N/A |
| 6-2 | N/A | N/A | 6-1 | 0-1 |
Last 5 Matchups
Team Stats
302
YDS
136
19/33
Comps/Atts
16/25
9.151515151515152
YPA
5.44
2/1
TDs/INTs
1/1
1/2
Sacks/Yards
1/9
1/5
Penalties/Yards
8/96
USC vs. Notre Dame Odds Comparison
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USC at Notre Dame Team Totals
MatchupOverUnder | ||
|---|---|---|
USC 6-2 | o24-113 | u24-117 |
Notre Dame 6-2 | o35.5-108 | u35.5-119 |