Cardinals vs. Chargers Odds & Betting Predictions - September 13, 2026

Cardinals at Chargers

8:25 pm • CBS

Arizona Cardinals

Los Angeles Chargers

MatchupOpenSpreadTotalMoneyline
Cardinals 0-0	+8.5	+10.5-115	o46.5-110	+455
Chargers 0-0	u46.5	-10.5-105	u46.5-110	-625

Sunday 8:25 p.m.

September 13, 2026

SoFi StadiumInglewood

NFL Schedule Release Betting Primer
Evan Abrams•
May 15, 2026 UTC

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NFL Public Betting

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Chargers	N/A	N/A	N/A	N/A	N/A
Cardinals	N/A	N/A	N/A	N/A	N/A

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Chargers	N/A	N/A	N/A	N/A	N/A
Cardinals	N/A	N/A	N/A	N/A	N/A

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Chargers	N/A	N/A	N/A	N/A	N/A
Cardinals	N/A	N/A	N/A	N/A	N/A

date	opponent	score	spread	over/under	moneyline
Jan 12th	@NE	L 3-16	+3.5 L	U 45.5	NE +159
Jan 4th	@DEN	L 3-19	+15.5 L	U 37.5	DEN +908
Dec 27th	HOU	L 16-20	-1.5 L	U 41	HOU -119
Dec 21st	@DAL	W 34-17	+1.5 W	O 50.5	LAC -102
Dec 14th	@KC	W 16-13	+5.5 W	U 41.5	LAC +222

James Conner
RB
Conner is out with foot
Out
Gardner Minshew
QB
Minshew is out with knee
Out
Bam Knight
RB
Knight is out with ankle
Out
Marvin Harrison
WR
Harrison is out with foot
Out
Trey Benson
RB
Benson is out with knee
Out
Tip Reiman
TE
Reiman is out with ankle
Out

David Njoku
TE
Njoku is out with knee
Out
KeAndre Lambert-Smith
WR
Lambert-Smith is out with hamstring
Out

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passing yards
Justin Herbert
3727
pyds
passing touchdowns
Justin Herbert
26
ptd
rushing yards
Kimani Vidal
643
ryds
rushing touchdowns
Omarion Hampton
4
rtd

	Starter	2ND	3RD	4TH
QB	Justin Herbert	Trey Lance	DJ Uiagalelei
RB	Omarion Hampton	Najee Harris	Kimani Vidal	Hassan Haskins	Jaret Patterson
WR	Ladd McConkey	Derius Davis	Luke Grimm
TE	Will Dissly	Tyler Conklin	Oronde Gadsden	Tucker Fisk	Thomas Yassmin
LT	Joe Alt	Jamaree Salyer
LG	Zion Johnson	Branson Taylor
C	Bradley Bozeman	Andre James	Josh Kaltenberger
RG	Mekhi Becton
RT	Trey Pipkins
RDE	Da'Shawn Hand	Justin Eboigbe	Scott Matlock
LCB	Donte Jackson	Deane Leonard
SS	Derwin James	Tony Jefferson	RJ Mickens
FS	Elijah Molden	Kendall Williamson
RCB	Cam Hart	Nikko Reed	Benjamin St-Juste	Eric Rogers
P	JK Scott
H	JK Scott
PR	Derius Davis	Ladd McConkey	KeAndre Lambert-Smith
KR	Derius Davis	Hassan Haskins	KeAndre Lambert-Smith
LS	Josh Harris
FB	Scott Matlock
RILB	Daiyan Henley	Junior Colson	Emany Johnson	Marlowe Wax
RWR	Keenan Allen	Quentin Johnston	Dalevon Campbell
LOLB	Tuli Tuipulotu	Kyle Kennard
LWR	Tre' Harris	KeAndre Lambert-Smith	JaQuae Jackson
ROLB	Khalil Mack	Bud Dupree	Garmon Randolph
LILB	Denzel Perryman	Troy Dye	Del'Shawn Phillips
NT	Teair Tart	Jamaree Caldwell	TeRah Edwards
NB	Tarheeb Still
DT	Otito Ogbonnia
K	Cameron Dicker

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MatchupOverUnder
Cardinals 0-0	N/A	N/A
Chargers 0-0	N/A	N/A

Cardinals vs. Chargers Odds & Betting Predictions - September 13, 2026

Cardinals at Chargers

Arizona Cardinals

Los Angeles Chargers

Cardinals at Chargers Odds

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Cardinals vs. Chargers Previews & Analysis

NFL Schedule Release Betting Primer

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