Astros vs. Angels Odds & Betting Predictions - September 28, 2025
Astros at Angels
7:07 pm • SCHNStarting Pitchers
pitcher | team | era | w-l | |
---|---|---|---|---|
![]() | ![]() | 7.90 | 0-2 | |
![]() | ![]() | 6.51 | 2-5 |
Astros at Angels Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Astros 87-75 | -1.5 | -1.5+134 | o9-104 | -117 |
![]() Angels 72-90 | u9.5 | +1.5-164 | u9-112 | -102 |

Angel StadiumAnaheim
Astros vs. Angels Expert Picks

Charlie Wright
Last 30d: 15-11-0 (+2.8u)
L.McCullers o3.5 Ks+128
1.28u
McCullers will make his return in what will be a meaningless game for Houston. He might not go more than 4-5 innings, but that’s plenty in this matchup. The Angels are the highest-strikeout team in the league vs. RHP and they’ve ramped it up in September. LA has an absurd 32.2% K% vs. RHP this month.
Prop Odds Comparison
Line Movement Tracker
Astros vs. Angels Public Betting Percentages
Betting Trends
- Angels are 2-3 in their last 5 games.
- Angels are 2-3 in their last 5 games against the spread
- Angels are 41-40 in their road games against the spread
- The totals have gone OVER in 1 of Angels' last 5 games
- The totals have gone OVER in 44 of Angels' 81 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Angels vs. Astros Injury Updates

Angels Injuries
- Anthony Rendon3B
Rendon is out with hip
Out
- Gustavo CamperoRF
Campero is out with ankle
Out

Astros Injuries
- Pedro LeonRF
Leon is out with knee
Out
- Hayden WesneskiRP
Wesneski is out with elbow
Out
Astros vs. Angels Box Score

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 54 | 3 | 4 | 1 | |
![]() | 68 | 5 | 3 | 0 | |
![]() | 24 | 1 | 2 | 1 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-5 | 1 | 0 | 0 |
![]() | 1-4 | 1 | 1 | 1 |
![]() | 2-5 | 1 | 1 | 2 |
![]() | 2-5 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 1-3 | 1 | 1 | 2 |
![]() | 2-4 | 1 | 1 | 1 |
![]() | 1-3 | 0 | 0 | 0 |

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 96 | 4.2 | 5 | 4 | |
![]() | 27 | 1.1 | 2 | 2 | |
![]() | 21 | 1 | 1 | 0 | |
![]() | 12 | 1 | 0 | 0 | |
![]() | 13 | 1 | 1 | 0 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-1 | 1 | 1 | 1 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 1 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
Astros vs. Angels Odds Comparison
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Astros at Angels Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Astros 87-75 | o4.5-110 | u4.5-117 |
![]() Angels 72-90 | o4.5+115 | u4.5-147 |