Astros vs. Athletics Odds & Betting Predictions - September 25, 2025

Astros at Athletics

2:05 am • SCHN

Houston Astros

@

Athletics

pitcher		team	era	w-l
L.Severino			4.72	7-11
H.Brown			2.30	12-8

MatchupOpenSpreadTotalMoneyline
Astros 84-73	-1.5	-1.5+125	o9-110	-132
Athletics 74-83	u9	+1.5-150	u9-110	+111

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Thursday 2:05 a.m.

September 25, 2025

Sutter Health ParkWest Sacramento

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79°Fahrenheit

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0%Rain

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7Wind

HOU -132

1u

L.Butler u0.5 Runs Scored-139

1.39u

ATH +125

0.5u

Bet to +115

L.Butler u0.5 Runs Scored-139

1u

Today's MLB Best Bets
Action Network Staff•
Sep 24, 2025 UTC

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MLB Public Betting

Athletics are 3-2 in their last 5 games.
Athletics are 2-3 in their last 5 games against the spread
Athletics are 47-34 in their road games against the spread
The totals have gone OVER in 1 of Athletics' last 5 games
The totals have gone OVER in 38 of Athletics' 76 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Athletics	84-73	37-39	47-34	14-23	68-48
Astros	79-78	37-44	42-34	40-58	39-18

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Athletics	75-74-8	38-36-2	37-38-6	14-21-2	59-51-6
Astros	71-79-7	36-43-2	35-36-5	44-52-2	25-27-5

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Athletics	74-83	34-42	40-41	17-20	54-62
Astros	84-73	46-35	38-38	53-45	31-26

date	opponent	score	spread	over/under	moneyline
Sep 24th	HOU	W 5-1	+1.5 W	U 10	ATH -116
Sep 21st	@PIT	L 0-11	-1.5 L	O 8.5	PIT +100
Sep 20th	@PIT	L 0-2	-1.5 L	U 8	PIT -113
Sep 19th	@PIT	W 4-3	-1.5 L	U 8.5	ATH -112
Sep 18th	@BOS	W 5-3	+1.5 W	U 9	ATH +126

Luis Medina
SP
Medina is out with elbow
Out
Brady Basso
RP
Basso is out with shoulder
Out

Pedro Leon
RF
Leon is out with knee
Out
Hayden Wesneski
RP
Wesneski is out with elbow
Out

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PITCHER		W-L	ERA	WHIP	K/9
RH.Brown, P		12-8	2.30	1.009	10.04

HITTERS	AVG	OBP	SLG	HR
1J.Altuve, 2B	.263	.325	.441	26
2C.Correa, SS	.267	.319	.386	7
3I.Paredes, DH	.254	.353	.464	20
4C.Walker, 1B	.234	.295	.400	23
5J.Sanchez, LF	.197	.274	.333	3
6Y.Diaz, C	.256	.284	.412	19
7J.Meyers, CF	.294	.356	.376	3
8Z.Cole, RF	.267	.333	.567	3
9R.Urias, 3B	.248	.300	.388	8

PITCHER		W-L	ERA	WHIP	K/9
RL.Severino, P		7-11	4.72	1.331	6.85

HITTERS	AVG	OBP	SLG	HR
1N.Kurtz, 1B	.291	.383	.612	33
2S.Langeliers, C	.259	.311	.514	30
3T.Soderstrom, LF	.278	.348	.473	24
4B.Rooker, DH	.264	.335	.485	30
5J.Wilson, SS	.318	.362	.453	13
6L.Butler, CF	.237	.308	.410	21
7M.Schuemann, 2B	.207	.302	.287	2
8J.Bleday, RF	.211	.296	.403	14
9B.Harris, 3B	.283	.353	.367	0

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MatchupOverUnder
Astros 84-73	N/A	N/A
Athletics 74-83	N/A	N/A