Astros vs. Athletics Odds & Betting Predictions - September 25, 2025

Astros at Athletics

7:35 pm • SCHN

Houston Astros

87-75

11 - 5

Athletics

76-86

pitcher		team	era	w-l
J.Ginn			5.08	4-7
F.Valdez			3.66	13-11

MatchupOpenSpreadTotalMoneyline
Astros 87-75	-1.5	-1.5+132	o9.5-110	-119
Athletics 76-86	u9.5	+1.5-162	u9.5-110	-101

Thursday 7:35 p.m.

September 25, 2025

Sutter Health ParkWest Sacramento

ATH +104

Over 9.5-107

1.4u

ATH +102

0.49u

Bet to -105

Under 9.5-105

0.53u

Projecting this closer to 9. Astros still playing for wild card so we’ll get their best. JT Ginn has really impressed with a 4.57 ERA but 3.71 xERA under the hood. I’ll back the pitching here even though it’s a hitter’s ballpark.

Astros vs Athletics: System-Backed Total Pick
Action Network Staff•
Sep 25, 2025 UTC

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No props found

MLB Public Betting

Athletics are 2-3 in their last 5 games.
Athletics are 2-3 in their last 5 games against the spread
Athletics are 47-34 in their road games against the spread
The totals have gone OVER in 2 of Athletics' last 5 games
The totals have gone OVER in 40 of Athletics' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Athletics	86-76	39-42	47-34	14-24	70-50
Astros	82-80	37-44	45-36	43-60	39-18

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Athletics	77-77-8	40-39-2	37-38-6	14-22-2	61-53-6
Astros	72-83-7	36-43-2	36-40-5	45-56-2	25-27-5

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Athletics	76-86	36-45	40-41	17-21	56-64
Astros	87-75	46-35	41-40	56-47	31-26

date	opponent	score	spread	over/under	moneyline
Sep 25th	HOU	W 6-0	+1.5 W	U 9	ATH +112
Sep 24th	HOU	W 5-1	+1.5 W	U 10	ATH -116
Sep 21st	@PIT	L 0-11	-1.5 L	O 8.5	PIT +100
Sep 20th	@PIT	L 0-2	-1.5 L	U 8	PIT -113
Sep 19th	@PIT	W 4-3	-1.5 L	U 8.5	ATH -112

Luis Medina
SP
Medina is out with elbow
Out

Pedro Leon
RF
Leon is out with knee
Out
Hayden Wesneski
RP
Wesneski is out with elbow
Out

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PITCHER	PC	IP	K	ER
LF.Valdez, P	92	7	10	1
RE.De Los Santos, P	18	1	1	2
RN.Hernandez, P	10	0	0	2
RB.Abreu, P	12	1	1	0

HITTERS	H-AB	R	HR	RBI
1J.Altuve, 2B	2-3	2	0	2
1R.Urias, PH	1-2	0	0	0
1R.Urias, 2B	1-2	0	0	0
2I.Paredes, DH	2-3	1	0	2
2Y.Diaz, PH	0-2	0	0	0
2Y.Diaz, DH	0-2	0	0	0
3C.Correa, 3B	1-3	1	0	2
4V.Caratini, C	1-4	0	0	1
5C.Walker, 1B	2-5	1	1	3
6J.Sanchez, RF	0-2	0	0	0
6C.Smith, PH	0-3	0	0	0
6C.Smith, RF	0-3	0	0	0
7Z.Cole, CF	1-5	1	0	0
8T.Trammell, LF	1-4	2	0	0
9M.Dubon, SS	1-3	3	0	1

PITCHER	PC	IP	K	ER
RJ.Ginn, P	81	3.2	4	7
LB.Basso, P	44	1	1	2
RO.Bido, P	37	2.1	3	1
RS.McGough, P	29	2	2	1

HITTERS	H-AB	R	HR	RBI
1S.Langeliers, DH	4-5	1	0	0
2J.Wilson, SS	0-3	0	0	0
2J.Bleday, RF	1-2	1	0	1
3T.Soderstrom, LF	0-3	0	0	0
3M.Muncy, SS	0-1	0	0	0
4B.Rooker, RF	0-2	0	0	0
4M.Schuemann, LF	0-3	0	0	1
5C.Thomas, CF	1-4	1	0	0
6N.Kurtz, 1B	3-5	2	2	3
7D.Hernaiz, 2B	1-4	0	0	0
8B.Harris, 3B	1-4	0	0	0
9W.MacIver, C	1-3	0	0	0