Astros vs. Orioles Odds & Betting Predictions - August 22, 2025

Astros at Orioles

11:05 pm • MLB Network
10 - 7
Starting Pitchers
pitcherteameraw-l
Cade Povich logoC.PovichBaltimore Orioles logo5.132-7
Lance McCullers logoL.McCullersHouston Astros logo6.892-4

Astros at Orioles Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Astros
72-58
-1.5
-1.5+137
o9.5-108
-116
Orioles
59-70
u9
+1.5-164
u9.5-114
-104
location pinFriday 11:05 p.m.
August 22, 2025
Oriole Park at Camden YardsBaltimore
Astros vs. Orioles Expert Picks
VegasIsMyBitch
VegasIsMyBitch
Last 30d: 18-19-1 (-0.8u)
Under 9+101
0.5u
1.5u play overall
Under 9+101
1u
Scott Rickenbach
Scott Rickenbach
Last 30d: 74-77-4 (-14.0u)
Over 9.5-111
0.9u
Player Prop Savant
Player Prop Savant
Last 30d: 22-36-0 (-15.8u)
HOU o4.5 Team Total-117
1.25u
Derek Carty
Derek Carty
Last 30d: 4-5-4 (+2.8u)
Samuel Basallo o0.5 Hitter BBs+280
1u
Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 5-16-0 (-8.3u)
Samuel Basallo o0.5 Hitter BBs+280
1u

Astros vs. Orioles Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Astros vs. Orioles Public Betting Percentages

Away Logo

Astros

Public

60%

Bets%

40%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Orioles
61-6828-3533-3321-3738-31
Astros
65-6530-3535-3035-5130-12

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Orioles
56-69-433-28-223-41-230-26-225-42-2
Astros
61-63-629-35-132-28-541-43-218-20-4

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Orioles
59-7030-3329-3725-3332-37
Astros
72-5838-2734-3147-3925-17

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Aug 21stHOUL 2-7+1.5 LO 8.5HOU -120
Aug 19th@BOSW 4-3+1.5 WU 9.5BAL +125
Aug 18th@BOSW 6-3-1.5 WO 8BAL +105
Aug 17th@HOUW 12-0-1.5 WO 8.5BAL -101
Aug 16th@HOUL 4-5+1.5 WO 8.5HOU +118

Astros vs. Orioles Injury Updates

Astros Injuries

  • Jake Meyers
    CF

    Meyers is out with calf

    Out

  • Luis Garcia
    SP

    Garcia is out with elbow

    Out

  • Pedro Leon
    RF

    Leon is out with knee

    Out

  • J.P. France
    SP

    France is out with shoulder

    Out

  • Hayden Wesneski
    RP

    Wesneski is out with elbow

    Out

Orioles Injuries

  • Albert Suarez
    RP

    Suarez is out with shoulder

    Out

  • Jorge Mateo
    SS

    Mateo is out with hamstring

    Out

  • Kyle Bradish
    SP

    Bradish is out with elbow

    Out

  • Grayson Rodriguez
    SP

    Rodriguez is out with elbow

    Out

  • Tyler Wells
    SP

    Wells is out with elbow

    Out

Astros vs. Orioles Box Score
Astros Player Stats
Projected
PITCHERPCIPKER
Lance McCullers logoRL.McCullers, P87443
Shawn Dubin logoRS.Dubin, P281.202
Steven Okert logoLS.Okert, P30.110
Enyel De Los Santos logoRE.De Los Santos, P19121
Kaleb Ort logoRK.Ort, P160.201
Bryan Abreu logoRB.Abreu, P211.140
HITTERSH-ABRHRRBI
Jeremy Pena logo1J.Pena, SS2-5114
Carlos Correa logo2C.Correa, 3B1-4100
Jose Altuve logo3J.Altuve, DH2-5100
Christian Walker logo4C.Walker, 1B1-5113
Yainer Diaz logo5Y.Diaz, C1-4000
Ramon Urias logo6R.Urias, 2B2-5100
Mauricio Dubon logo7M.Dubon, LF0-3100
Cam Smith logo8C.Smith, RF0-3100
Jesus Sanchez logo8J.Sanchez, PH0-1100
Jesus Sanchez logo8J.Sanchez, RF0-1100
Chas McCormick logo9C.McCormick, CF0-1100
Victor Caratini logo9V.Caratini, PH1-1002
Jacob Melton logo9J.Melton, PR0-0100
Jacob Melton logo9J.Melton, CF0-0100
Orioles Player Stats
Projected
PITCHERPCIPKER
Cade Povich logoLC.Povich, P964.254
Yennier Cano logoRY.Cano, P120.111
Kade Strowd logoRK.Strowd, P12100
Matt Bowman logoRM.Bowman, P161.112
Corbin Martin logoRC.Martin, P201.221
HITTERSH-ABRHRRBI
Jackson Holliday logo1J.Holliday, 2B1-3001
Jeremiah Jackson logo2J.Jackson, RF2-5003
Gunnar Henderson logo3G.Henderson, SS2-5000
Ryan Mountcastle logo4R.Mountcastle, DH1-4000
Colton Cowser logo5C.Cowser, CF1-5111
Coby Mayo logo6C.Mayo, 1B0-3100
Dylan Beavers logo7D.Beavers, LF1-3200
Luis Vazquez logo8L.Vazquez, 3B2-3100
Samuel Basallo logo8S.Basallo, PH0-2000
Samuel Basallo logo8S.Basallo, C0-2000
Alex Jackson logo9A.Jackson, C2-3101
Vimael Machin logo9V.Machin, 3B1-2111

Astros vs. Orioles Odds Comparison

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Astros at Orioles Team Totals

MatchupOverUnder
Astros
72-58
o4.5-120
u4.5-108
Orioles
59-70
o4.5+101
u4.5-130