Brewers vs. Cubs Odds & Betting Predictions - August 21, 2025

Brewers at Cubs

12:05 am • FDSWI

Milwaukee Brewers

80-48

3 - 4

Chicago Cubs

73-55

pitcher		team	era	w-l
C.Rea			3.96	10-5
J.Misiorowski			4.19	4-2

MatchupOpenSpreadTotalMoneyline
Brewers 80-48	+1.5	-1.5+150	o6.5-120	-120
Cubs 73-55	u7	+1.5-182	u6.5-103	+100

Thursday 12:05 a.m.

August 21, 2025

Wrigley FieldChicago

Under 3.5 (F5)-105

1.05u

CHC +105

0.53u

Bet to -102

MIL -115

1.15u

C.Rea o16.5 Outs-110

1.04u

Under 7-115

MIL -119

Under 7-112

📊 49-19 W/L (72.06%) ROI ~ 35.98% L10 ~ 8-2 📈 Cubs Home Under’s After ASB since 2022 ✅ Team is at home ✅ Team is Cubs ✅ Game number in season is more than 100 ✅ Teams ML is less than -160

MIL -115

1.15u

CHC -102

2.94u

Brewers vs Cubs: Who To Back on Wednesday Night
Nick Martin•
Aug 20, 2025 UTC

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No props found

MLB Public Betting

Cubs are 3-2 in their last 5 games.
Cubs are 3-2 in their last 5 games against the spread
Cubs are 30-32 in their road games against the spread
The totals have gone OVER in 2 of Cubs' last 5 games
The totals have gone OVER in 30 of Cubs' 66 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cubs	61-67	31-35	30-32	44-46	17-21
Brewers	75-53	33-29	42-24	34-33	40-20

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cubs	59-62-7	30-32-4	29-30-3	39-46-5	20-16-2
Brewers	60-65-3	28-33-1	32-32-2	35-31-1	25-33-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cubs	73-55	41-25	32-30	57-33	16-22
Brewers	80-48	42-20	38-28	46-21	33-27

date	opponent	score	spread	over/under	moneyline
Aug 20th	MIL	W 4-1	+1.5 W	U 6.5	CHC +102
Aug 19th	MIL	W 6-4	-1.5 W	O 7	CHC -158
Aug 18th	MIL	L 0-7	+1.5 L	U 8	MIL -115
Aug 17th	PIT	W 4-3	-1.5 L	U 7	CHC -198
Aug 16th	PIT	W 3-1	-1.5 W	U 8.5	CHC -229

Jordan Montgomery
SP
Montgomery is out for season with elbow
Out for Season
Rhys Hoskins
1B
Hoskins is out with thumb
Out
Easton McGee
SP
McGee is out with arm
Out
Garrett Mitchell
CF
Mitchell is out with oblique
Out
Aaron Ashby
RP
Ashby is out with oblique
Out
Robert Gasser
SP
Gasser is out with elbow
Out

Jameson Taillon
SP
Taillon is out with calf
Out
Michael Soroka
SP
Soroka is out with shoulder
Out
Justin Steele
SP
Steele is out for season with elbow
Out for Season

See more MLB Injuries

PITCHER	PC	IP	K	ER
RJ.Misiorowski, P	78	4	5	3
RN.Mears, P	9	1	1	0
RS.Miller, P	18	1	2	0
RA.Uribe, P	6	1	1	0
LJ.Koenig, P	18	1	0	1

HITTERS	H-AB	R	RBI
1S.Frelick, RF	1-4	0	0
2I.Collins, LF	0-3	0	0
3W.Contreras, C	0-5	0	0
4C.Yelich, DH	0-2	2	0
5A.Vaughn, 1B	1-4	0	0
6A.Seigler, 3B	0-3	0	0
7B.Turang, 2B	3-3	1	1
8B.Perkins, CF	0-3	0	1
8C.Durbin, PH	0-1	0	0
9J.Ortiz, SS	0-3	0	0
9D.Jansen, PH	1-1	0	1
9B.Lockridge, PR	0-0	0	0

PITCHER	PC	IP	K	ER
RC.Rea, P	96	5.2	3	2
LC.Thielbar, P	17	1.1	2	0
RB.Keller, P	10	1	1	0
RD.Palencia, P	28	1	2	1

HITTERS	H-AB	R	HR	RBI
1M.Busch, 1B	2-4	0	0	3
2I.Happ, LF	0-4	0	0	0
3S.Suzuki, DH	1-4	0	0	0
4P.Crow-Armstrong, CF	0-3	0	0	0
5C.Kelly, C	0-3	0	0	0
6N.Hoerner, 2B	0-3	0	0	0
7O.Caissie, RF	0-2	1	0	0
8D.Swanson, SS	0-2	1	0	0
9M.Shaw, 3B	1-2	2	1	1