Cardinals vs. Brewers Odds & Betting Predictions - May 25, 2026

Cardinals at Brewers

6:10 pm • BREW
1 - 5
Starting Pitchers
pitcherteameraw-l
Jacob Misiorowski logoJ.MisiorowskiMilwaukee Brewers logo1.458-3
Matthew Liberatore logoM.LiberatoreSt. Louis Cardinals logo5.233-4

Cardinals at Brewers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cardinals
42-34
+1.5
+1.5-115
o7.5-101
+193
Brewers
47-29
u7.5
-1.5-105
u7.5-114
-238
location pinMonday 6:10 p.m.
May 25, 2026
American Family FieldMilwaukee
Cardinals vs. Brewers Expert Picks
The Propfessor
The Propfessor
Last 30d: 30-45-0 (+12.0u)
J.Misiorowski o17.5 Outs-150
0.67u
Picks Office
Picks Office
Last 30d: 142-142-13 (-11.0u)
Under 4 (F5)+100
1u
Join Discord for earlier access: https://discord.gg/HjKxYKdSUy Misiorowski anchors the first-five under with a 1.89 ERA, 0.88 WHIP, and 88 K in 57 innings. Liberatore is the risk at 4.70 ERA and 1.55 WHIP, but F5 Under 4 gives push protection if the early score lands on 4. Dome roof in, full-game total 7.5, and the cleanest under path is Milwaukee's starter controlling St. Louis early.
The Degenerates
The Degenerates
Last 30d: 51-69-4 (-22.9u)
MIL -1.5+100
1u
Doug Ziefel
Doug Ziefel
Last 30d: 161-189-11 (-4.3u)
J.Misiorowski u17.5 Outs+150
0.33u
Anthony Dabbundo
Anthony Dabbundo
Last 30d: 38-39-3 (-5.6u)
MIL -212
1u
💰🦡 Jake
💰🦡 Jake
Last 30d: 61-85-2 (-16.8u)
Over 7.5+100
1u
Sandy Plashkes
Sandy Plashkes
Last 30d: 89-130-3 (-23.4u)
MIL -1.5-115
1u
Doug Ziefel
Doug Ziefel
Last 30d: 161-189-11 (-4.3u)
Under 7.5-105
0.5u
Ryan Minion
Ryan Minion
Last 30d: 293-289-17 (+54.0u)
MIL -1.5-105
$1.00
J.Chourio o1.5 Total Bases-110
$1.10
MIL -0.5 (F5)-140
$1.00
Frank Ammirante
Frank Ammirante
Last 30d: 329-277-11 (+55.5u)
STL u1.5 (F5)-145
1u
Sean Zerillo
Sean Zerillo
Last 30d: 153-129-9 (+4.1u)
MIL -205
0.5u
Bet to -240

Cardinals vs. Brewers Previews & Analysis

  • The Leadoff: Anderson's MLB Breakdown & Bets for Monday article feature image

    The Leadoff: Anderson's MLB Breakdown & Bets for Monday

    Jon Anderson
    May 25, 2026 UTC
  • Our 4 MLB Best Bets for Memorial Day Afternoon article feature image

    Our 4 MLB Best Bets for Memorial Day Afternoon

    Action Network Staff
    May 25, 2026 UTC
  • Cardinals vs Brewers: System-Based Over/Under Pick article feature image

    Cardinals vs Brewers: System-Based Over/Under Pick

    Action Network Staff
    May 25, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Cardinals vs. Brewers Public Betting Percentages

Away Logo

Cardinals

Public

13%

Bets%

87%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Brewers
43-3323-1720-1628-2415-9
Cardinals
45-3122-1723-1410-835-22

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Brewers
34-40-218-2216-18-225-26-19-14-1
Cardinals
33-39-417-20-216-19-27-10-125-29-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Brewers
47-2925-1522-1434-1813-11
Cardinals
42-3422-1720-1713-529-28

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 24thLADL 1-5+1.5 LU 8LAD +125
May 23rdLADL 3-11+1.5 LO 8.5LAD -105
May 22ndLADW 5-1+1.5 WU 8MIL -110
May 20th@CHCW 5-0-1.5 WU 6.5MIL +104
May 19th@CHCW 5-2-1.5 WU 7.5MIL -123

Cardinals vs. Brewers Injury Updates

Cardinals Injuries

  • Masyn Winn
    SS

    Masyn Winn (thumb) has been scratched Tuesday.

    Out

Brewers Injuries

  • Akil Baddoo
    LF

    Baddoo is out with quad

    Out

  • Quinn Priester
    SP

    Priester is out with wrist

    Out

  • Drew Rom
    SP

    Rom is out with biceps

    Out

Cardinals vs. Brewers Box Score
Cardinals Player Stats
Projected
PITCHERPCIPKER
Matthew Liberatore logoLM.Liberatore, P1015103
Brycen Mautz logoLB.Mautz, P59322
HITTERSH-ABRHRRBI
JJ Wetherholt logo1J.Wetherholt, 2B1-3000
Ivan Herrera logo2I.Herrera, DH0-4001
Alec Burleson logo3A.Burleson, 1B0-4000
Jordan Walker logo4J.Walker, RF0-3000
Nolan Gorman logo5N.Gorman, 3B0-3000
Masyn Winn logo6M.Winn, SS0-3000
Bryan Torres logo7B.Torres, LF0-3000
Bryan Torres logo7B.Torres, CF0-3000
Pedro Pages logo8P.Pages, C1-3000
Victor Scott logo9V.Scott, CF0-2100
Jose Fermin logo9J.Fermin, PH0-1000
Jose Fermin logo9J.Fermin, LF0-1000
Brewers Player Stats
Projected
PITCHERPCIPKER
Jacob Misiorowski logoRJ.Misiorowski, P967121
Aaron Ashby logoLA.Ashby, P21210
HITTERSH-ABRHRRBI
Jackson Chourio logo1J.Chourio, LF0-3100
Brice Turang logo2B.Turang, 2B0-3100
William Contreras logo3W.Contreras, C1-3101
Christian Yelich logo4C.Yelich, DH2-4112
Andrew Vaughn logo5A.Vaughn, 1B3-4101
Luis Rengifo logo6L.Rengifo, 3B2-3000
Blake Perkins logo7B.Perkins, RF0-4000
Garrett Mitchell logo8G.Mitchell, CF2-4001
Joey Ortiz logo9J.Ortiz, SS1-4000

Cardinals vs. Brewers Odds Comparison

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Cardinals at Brewers Team Totals

MatchupOverUnder
Cardinals
42-34
N/A
N/A
Brewers
47-29
N/A
N/A