Guardians vs. Diamondbacks Odds & Betting Predictions - August 20, 2025

Guardians at Diamondbacks

1:40 am • MLB Network

Cleveland Guardians

5-3

5 - 6

Arizona Diamondbacks

4-5

pitcher		team	era	w-l
E.Rodriguez			5.01	9-9
T.Bibee			4.25	12-11

MatchupOpenSpreadTotalMoneyline
Guardians 5-3	+1.5	-1.5+319	o8.5-121	+100
Diamondbacks 4-5	u9	+1.5-190	u8.5-101	-120

Wednesday 1:40 a.m.

August 20, 2025

Chase FieldPhoenix

ARI -115

1.74u

Arizona has the edge tonight with Tanner Bibee’s biggest weakness exposed. He’s giving up 1.45 HR/9, and Chase Field doesn’t forgive mistakes. One swing from the D-backs middle order can flip this game fast. That’s the cleanest path to a home win. Eduardo Rodríguez isn’t perfect with a 5.40 ERA, but his strikeout punch at 9.08 K/9 gives him the tools to strand runners when needed. If he limits traffic early, he can hand this game to Arizona’s bullpen with a lead, which is all the D-backs need. Series urgency also matters. Arizona already dropped Game 1 and can’t afford to fall behind at home. With the roof closed, no weather randomness plays in. Execution wins, and the D-backs have the power bats and strikeout arm to even this series.

Under 9-120

@Zerillo

Under 9-110

0.55u

Projecting this closer to 8

Under 9-102

0.51u

Bet to -112

ARI -115

CLE 85/80/71 wRC+ Rd/v LHP/L7 days, ARI 117/116/118 and maybe the best base running team in the league too.

Guardians vs Diamondbacks: Moneyline Pick for Tuesday Night
John Feltman•
Aug 19, 2025 UTC
Zerillo's Opening Pitch for Tuesday
Sean Zerillo•
Aug 19, 2025 UTC

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No props found

MLB Public Betting

Diamondbacks are 3-2 in their last 5 games.
Diamondbacks are 3-2 in their last 5 games against the spread
Diamondbacks are 2-1 in their road games against the spread
The totals have gone OVER in 2 of Diamondbacks' last 5 games
The totals have gone OVER in 3 of Diamondbacks' 6 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Diamondbacks	6-3	4-2	2-1	2-1	3-2
Guardians	5-3	1-0	4-3	1-0	4-3

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Diamondbacks	5-4	3-3	2-1	1-2	3-2
Guardians	3-5	0-1	3-4	0-1	3-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Diamondbacks	4-5	4-2	0-3	2-1	1-4
Guardians	5-3	1-0	4-3	1-0	4-3

date	opponent	score	spread	over/under	moneyline
Aug 19th	CLE	L 1-3	+1.5 L	U 9	CLE -123
Aug 17th	@COL	L 5-6	-1.5 L	U 12	COL -155
Aug 17th	@COL	L 7-10	-1.5 L	O 11.5	COL -175
Aug 16th	@COL	L 3-4	-1.5 L	U 12	COL -199
Aug 15th	@COL	W 8-2	-1.5 W	U 13	ARI -175

Corbin Burnes
SP
Burnes is out with elbow
Out
Lourdes Gurriel
LF
Gurriel is out with knee
Out
Merrill Kelly
SP
Kelly is out with back
Out
Blake Walston
SP
Walston is out with elbow
Out
Tyler Locklear
1B
Locklear is out with elbow
Out

Cristian Mena
SP
Mena is doubtful with shoulder
Doubtful

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PITCHER	PC	IP	K	ER
RT.Bibee, P	92	5.2	5	4
LE.Sabrowski, P	4	0.1	0	0
LT.Herrin, P	12	0.2	0	2
RN.Enright, P	7	0.1	0	0
RJ.Junis, P	8	1	1	0

HITTERS	H-AB	R	HR	RBI
1S.Kwan, LF	0-4	0	0	0
2A.Martinez, CF	2-5	1	0	0
3J.Ramirez, 3B	1-3	2	1	2
4D.Fry, DH	0-2	0	0	0
4K.Manzardo, PH	0-2	0	0	0
4K.Manzardo, DH	0-2	0	0	0
5C.Santana, 1B	1-5	1	0	1
6G.Arias, SS	1-4	1	0	0
7N.Jones, RF	2-4	0	0	1
8B.Rocchio, 2B	0-3	0	0	0
9A.Hedges, C	1-3	0	0	1
9B.Naylor, PR	0-0	0	0	0
9B.Naylor, C	0-0	0	0	0

PITCHER	PC	IP	K	ER
LE.Rodriguez, P	96	6.2	4	4
RJ.Burgos, P	4	0.1	0	0
RA.Hoffmann, P	22	0.2	0	1
LK.Backhus, P	11	0.1	0	0
LA.Saalfrank, P	9	1	1	0

HITTERS	H-AB	R	HR	RBI
1G.Perdomo, SS	2-3	2	0	1
2K.Marte, 2B	0-3	0	0	0
3C.Carroll, RF	2-4	2	0	1
4L.Gurriel, DH	1-4	0	0	3
5P.Smith, 1B	1-4	0	0	0
6B.Alexander, 3B	0-3	0	0	0
7J.McCarthy, LF	2-4	1	1	1
8A.Thomas, CF	1-4	1	0	0
9J.Herrera, C	0-3	0	0	0