Guardians vs. Diamondbacks Odds & Betting Predictions - August 20, 2025
Guardians at Diamondbacks
1:40 am • MLB NetworkStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 5.01 | 9-9 | ||
![]() | 4.25 | 12-11 |
Guardians at Diamondbacks Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Guardians 40-36 | +1.5 | -1.5+319 | o8.5-121 | +100 |
Diamondbacks 39-36 | u9 | +1.5-190 | u8.5-101 | -120 |

Chase FieldPhoenix
Guardians vs. Diamondbacks Expert Picks
Picks Office
Last 30d: 124-117-10 (-0.8u)
ARI -115
1.74u
Arizona has the edge tonight with Tanner Bibee’s biggest weakness exposed. He’s giving up 1.45 HR/9, and Chase Field doesn’t forgive mistakes. One swing from the D-backs middle order can flip this game fast. That’s the cleanest path to a home win.
Eduardo Rodríguez isn’t perfect with a 5.40 ERA, but his strikeout punch at 9.08 K/9 gives him the tools to strand runners when needed. If he limits traffic early, he can hand this game to Arizona’s bullpen with a lead, which is all the D-backs need.
Series urgency also matters. Arizona already dropped Game 1 and can’t afford to fall behind at home. With the roof closed, no weather randomness plays in. Execution wins, and the D-backs have the power bats and strikeout arm to even this series.
Payoff Pitch Podcast
Last 30d: 54-92-9 (-14.5u)
Under 9-120
1u
@Zerillo
Allan Lem
Last 30d: 22-17-1 (+1.9u)
Under 9-110
0.55u
Projecting this closer to 8

Sean Zerillo
Last 30d: 145-124-9 (+0.5u)
Under 9-102
0.51u
Bet to -112
Matt Trollo
Last 30d: 67-71-8 (-4.4u)
ARI -115
1u
CLE 85/80/71 wRC+ Rd/v LHP/L7 days, ARI 117/116/118 and maybe the best base running team in the league too.
Guardians vs. Diamondbacks Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Guardians vs. Diamondbacks Public Betting Percentages
Betting Trends
- Diamondbacks are 4-1 in their last 5 games.
- Diamondbacks are 3-2 in their last 5 games against the spread
- Diamondbacks are 20-16 in their road games against the spread
- The totals have gone OVER in 1 of Diamondbacks' last 5 games
- The totals have gone OVER in 15 of Diamondbacks' 39 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 43-32 | 23-16 | 20-16 | 18-17 | 24-15 | |
| 40-36 | 19-17 | 21-19 | 18-23 | 22-13 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 32-40-3 | 15-23-1 | 17-17-2 | 12-22-1 | 19-18-2 | |
| 37-39 | 18-18 | 19-21 | 21-20 | 16-19 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 39-36 | 24-15 | 15-21 | 22-13 | 16-23 | |
| 40-36 | 19-17 | 21-19 | 22-19 | 18-17 |
Last 5 Matchups
Guardians vs. Diamondbacks Injury Updates

Guardians Injuries

Diamondbacks Injuries
- Corbin BurnesSP
Burnes is out with elbow
Out
- Blake WalstonSP
Walston is out with elbow
Out
- Tyler Locklear1B
Locklear is out with elbow
Out
- Cristian MenaSP
Mena is doubtful with shoulder
Doubtful
Guardians vs. Diamondbacks Box Score
Guardians Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 92 | 5.2 | 5 | 4 | |
![]() | 4 | 0.1 | 0 | 0 | |
![]() | 12 | 0.2 | 0 | 2 | |
![]() | 7 | 0.1 | 0 | 0 | |
![]() | 8 | 1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 0-4 | 0 | 0 | 0 |
![]() | 2-5 | 1 | 0 | 0 |
![]() | 1-3 | 2 | 1 | 2 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 1-5 | 1 | 0 | 1 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 1 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 1 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
Diamondbacks Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 96 | 6.2 | 4 | 4 | |
![]() | 4 | 0.1 | 0 | 0 | |
![]() | 22 | 0.2 | 0 | 1 | |
![]() | 11 | 0.1 | 0 | 0 | |
![]() | 9 | 1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 2-3 | 2 | 0 | 1 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 2-4 | 2 | 0 | 1 |
![]() | 1-4 | 0 | 0 | 3 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 2-4 | 1 | 1 | 1 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
Guardians vs. Diamondbacks Odds Comparison
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Guardians at Diamondbacks Team Totals
MatchupOverUnder | ||
|---|---|---|
Guardians 40-36 | N/A | N/A |
Diamondbacks 39-36 | N/A | N/A |
































