Mariners vs. Padres Odds & Betting Predictions - April 16, 2026

Mariners at Padres

1:40 am • SDPA

Seattle Mariners

41-39

6 - 7

San Diego Padres

41-37

pitcher		team	era	w-l
R.Vasquez			4.17	6-5
E.Hancock			3.60	5-4

MatchupOpenSpreadTotalMoneyline
Mariners 41-39	-1.5	PK-123	o8-105	-111
Padres 41-37	u8	PK+174	u8-116	-109

Thursday 1:40 a.m.

April 16, 2026

Petco ParkSan Diego

Over 7.5 (Live)-110

Over 8-105

0.95u

Join Discord. All picks posted before 8am https://discord.gg/HjKxYKdSUy

R.Vasquez o4.5 Ks+120

0.6u

(FD) Velo up - 12+ SwStr% all 3 starts - SEA not K'ing as much as LY, but LU avg 22.1% v RHP since LY

SEA -105

0.53u

Increasing - No Tatis. Bet to -125

SEA -105

1.05u

R.Vasquez u4.5 Ks-155

Under 4.5 (F5)-120

$1.20

SEA -104

0.3u

Under 0.5 (1st Inn)-130

$1.00

SEA -104

0.52u

Update: Bet to -125 after lineups

Under 8-105

1.05u

Park, weather, umpire all support lower scoring game - both SPs have shown legit improvement - two of the best bullpens in the game.

Zerillo's Opening Pitch for Wednesday
Sean Zerillo•
Apr 16, 2026 UTC
Our 3 MLB Best Bets for Wednesday
Action Network Staff•
Apr 15, 2026 UTC
Mariners vs Padres: Back the Better Offense and Bullpen
Sean Zerillo•
Apr 15, 2026 UTC

See more MLB Coverage

No props found

MLB Public Betting

Padres are 3-2 in their last 5 games.
Padres are 4-1 in their last 5 games against the spread
Padres are 21-17 in their road games against the spread
The totals have gone OVER in 3 of Padres' last 5 games
The totals have gone OVER in 17 of Padres' 40 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Padres	43-35	22-18	21-17	17-17	26-18
Mariners	30-50	15-26	15-24	28-46	2-4

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Padres	34-43-1	17-22-1	17-21	13-20-1	21-23
Mariners	37-40-3	19-21-1	18-19-2	35-36-3	2-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Padres	41-37	21-19	20-18	19-15	22-22
Mariners	41-39	22-19	19-20	39-35	2-4

date	opponent	score	spread	over/under	moneyline
Apr 15th	SEA	W 4-1	+1.5 W	U 7	SD +100
Apr 12th	COL	W 7-2	-1.5 W	O 7.5	SD -225
Apr 12th	COL	W 9-5	-1.5 W	O 8.5	SD -170
Apr 11th	COL	W 5-2	-1.5 W	U 8	SD -174
Apr 10th	COL	W 7-3	-1.5 W	O 7.5	SD -185

Joe Musgrove
SP
Musgrove is out with elbow
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RE.Hancock, P	98	6	6	2
RE.Bazardo, P	11	1	0	0
LG.Speier, P	12	1	0	0
RA.Munoz, P	26	0.2	1	5
LJ.Ferrer, P	5	0	0	0

HITTERS	H-AB	R	HR	RBI
1B.Donovan, 3B	1-3	0	0	2
2C.Raleigh, C	1-4	0	0	0
3J.Rodriguez, CF	0-4	0	0	0
4J.Naylor, 1B	0-5	0	0	0
5R.Arozarena, LF	2-4	3	0	0
6L.Raley, RF	4-5	2	1	2
7D.Canzone, DH	1-4	0	0	2
8C.Young, 2B	0-4	1	0	0
9L.Rivas, SS	1-3	0	0	0

PITCHER	PC	IP	K	ER
RR.Vasquez, P	85	4	6	4
RR.Marinaccio, P	42	2	2	2
LW.Peralta, P	25	1	1	0
RA.Jacob, P	34	2	3	0

HITTERS	H-AB	R	HR	RBI
1R.Laureano, LF	2-5	1	0	1
2J.Merrill, CF	2-5	1	0	2
3X.Bogaerts, SS	2-4	1	1	2
4M.Machado, 3B	0-3	1	0	0
5G.Sheets, DH	2-4	1	0	0
6N.Castellanos, RF	0-4	0	0	0
7T.France, 1B	1-4	1	0	0
8J.Cronenworth, 2B	0-2	0	0	0
8F.Tatis, PH	0-0	0	0	1
9F.Fermin, C	0-0	0	0	0
9L.Campusano, C	1-4	1	0	1