Pirates vs. Cardinals Odds & Betting Predictions - May 6, 2025

Pirates at Cardinals

11:45 pm • FDSMW
1 - 2
Starting Pitchers
pitcherteameraw-l
Matthew Liberatore logoM.LiberatoreSt. Louis Cardinals logo3.073-3
Paul Skenes logoP.SkenesPittsburgh Pirates logo2.773-4

Pirates at Cardinals Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Pirates
12-25
-1.5
-1.5+145
o7-118
-118
Cardinals
18-19
u7
+1.5-175
u7-102
+100
location pinTuesday 11:45 p.m.
May 06, 2025
Busch StadiumSt. Louis
Pirates vs. Cardinals Expert Picks
Steak Friend
Steak Friend
Last 30d: 242-267-4 (-15.5u)
STL +100
1u
💰🦡 Jake
💰🦡 Jake
Last 30d: 125-130-4 (+3.3u)
Under 3.5 (F5)+100
1u
Markus Markets
Markus Markets
Last 30d: 39-42-1 (-7.3u)
J.Triolo u1.5 Hits + Runs + RBIs-160
0.63u
Sandy Plashkes
Sandy Plashkes
Last 30d: 102-123-15 (-22.2u)
P.Skenes o6.5 Ks+126
1u
Billy Ward
Billy Ward
Last 30d: 35-49-2 (-12.4u)
Under 0.5 (1st Inn)-145
1u
DK line
Jim Sannes
Jim Sannes
Last 30d: 30-50-1 (-6.2u)
M.Liberatore o5.5 Ks+148
1.48u
in the alt. market on FanDuel. Liberatore has been increasing his curve usage in recent starts, which has allowed him to get more whiffs against righties. He had seven strikeouts against the Pirates earlier this year, and their active roster has a 24.7% strikeout rate against lefties since the start of last year.
Boomer Betz
Boomer Betz
Last 30d: 171-179-3 (+46.4u)
PIT -125
1u
Sean Zerillo
Sean Zerillo
Last 30d: 165-162-18 (-0.7u)
STL +115
0.58u
Bet to +110

Pirates vs. Cardinals Previews & Analysis

  • Zerillo's Tuesday MLB Predictions & Betting Card article feature image

    Zerillo's Tuesday MLB Predictions & Betting Card

    Sean Zerillo
    May 6, 2025 UTC
  • Pirates vs Cardinals: Razor Thin Margins article feature image

    Pirates vs Cardinals: Razor Thin Margins

    Collin Whitchurch
    May 6, 2025 UTC
  • 3 MLB NRFI & YRFI Picks for Tuesday article feature image

    3 MLB NRFI & YRFI Picks for Tuesday

    Billy Ward
    May 6, 2025 UTC
See more MLB Coverage Right Arrow

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

Pirates vs. Cardinals Public Betting Percentages

Away Logo

Pirates

Public

53%

Bets%

47%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cardinals
18-1912-86-112-815-11
Pirates
13-247-126-124-119-13

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cardinals
21-14-211-8-110-6-17-2-113-12-1
Pirates
16-19-210-8-16-11-16-910-10-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cardinals
18-1914-64-134-613-13
Pirates
12-257-125-135-107-15

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 5thPITW 6-3-1.5 WO 8.5STL -132
May 4thNYMW 5-4+1.5 WO 7.5STL +136
May 4thNYMW 6-5+1.5 WO 8.5STL +102
May 3rdNYML 3-9+1.5 LO 7.5NYM +100
May 1st@CINL 1-9---

Cardinals vs. Pirates Injury Updates

Cardinals Injuries

    Pirates Injuries

    • Johan Oviedo
      P

      Oviedo is questionable with elbow

      Questionable

    • Jared Jones
      P

      Jones is out with elbow

      Out

    • Jared Triolo
      IF

      Triolo is questionable with back

      Questionable

    • Spencer Horwitz
      IF

      Horwitz is questionable with wrist

      Questionable

    Pirates vs. Cardinals Box Score
    Pirates Player Stats
    Projected
    PITCHERPCIPKER
    Paul Skenes logoRP.Skenes, P102662
    Dennis Santana logoRD.Santana, P14110
    David Bednar logoRD.Bednar, P15110
    HITTERSH-ABRHRRBI
    Oneil Cruz logo1O.Cruz, CF0-3100
    Bryan Reynolds logo2B.Reynolds, RF0-4000
    Andrew McCutchen logo3A.McCutchen, DH1-3000
    Ke'Bryan Hayes logo4K.Hayes, 3B2-4001
    Alexander Canario logo5A.Canario, LF0-3000
    Adam Frazier logo5A.Frazier, PH0-1000
    Matt Gorski logo6M.Gorski, 1B0-3000
    Enmanuel Valdez logo6E.Valdez, PH0-1000
    Jared Triolo logo7J.Triolo, SS0-3000
    Joey Bart logo7J.Bart, PH0-1000
    Liover Peguero logo8L.Peguero, 2B1-3000
    Henry Davis logo9H.Davis, C0-2000
    Cardinals Player Stats
    Projected
    PITCHERPCIPKER
    Matthew Liberatore logoLM.Liberatore, P99781
    Steven Matz logoLS.Matz, P18110
    Gordon Graceffo logoRG.Graceffo, P6100
    HITTERSH-ABRHRRBI
    Lars Nootbaar logo1L.Nootbaar, LF0-3000
    Masyn Winn logo2M.Winn, SS0-4000
    Brendan Donovan logo3B.Donovan, 2B1-4000
    Nolan Arenado logo4N.Arenado, 3B1-4100
    Willson Contreras logo5W.Contreras, DH0-1100
    Alec Burleson logo6A.Burleson, 1B1-3002
    Yohel Pozo logo7Y.Pozo, C0-3000
    Jordan Walker logo8J.Walker, RF0-2000
    Victor Scott logo9V.Scott, CF1-3000

    Pirates vs. Cardinals Odds Comparison

    Right Arrow

    Could not load odds

    Pirates at Cardinals Team Totals

    MatchupOverUnder
    Pirates
    12-25
    o3.5-118
    u3.5-110
    Cardinals
    18-19
    o3.5+105
    u3.5-140