Red Sox vs. Guardians Odds & Betting Predictions - May 29, 2026

Red Sox at Guardians

11:10 pm • CLEG
3 - 4
Starting Pitchers
pitcherteameraw-l
Slade Cecconi logoS.CecconiCleveland Guardians logo4.483-6
Tyler Samaniego logoT.SamaniegoBoston Red Sox logo2.660-3

Red Sox at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Red Sox
31-45
+1.5
+1.5-205
o8-111
+106
Guardians
41-38
u7.5
-1.5+169
u8-109
-126
location pinFriday 11:10 p.m.
May 29, 2026
Progressive FieldCleveland
Red Sox vs. Guardians Expert Picks
The Degenerates
The Degenerates
Last 30d: 51-69-4 (-22.9u)
CLE -124
1u
Alex Hinton
Alex Hinton
Last 30d: 71-71-1 (+12.6u)
W.Contreras To Record 2+ Total Bases Yes+130
1.3u
💰🦡 Jake
💰🦡 Jake
Last 30d: 61-85-2 (-16.8u)
BOS o3.5-120
1u
Kyle Murray
Kyle Murray
Last 30d: 67-112-1 (-32.5u)
CLE -120
1u
MJC Locks
MJC Locks
Last 30d: 5-9-0 (+0.3u)
J.Duran o1.5 Hits + Runs + RBIs-107
1u
Love today’s matchup for Jarren Duran against Slade Cecconi. Duran is heating up, hitting .340 over his last 11 games. He has 2+ HRRs in 7/L10 with 5+ PAs which I’m expecting again here (5+ PAs in 12/L13). He’s also hit 17/L21 Batted Balls vs RHP 92+ MPH 🔥 He has great numbers vs Cecconi’s pitch mix — primarily fastballs (4-Seam, Cutter, Sinker) & a Curve vs LHBs Cecconi has not been good this season either: 🥶 26th Percentile xERA (4.71) 🥶 21st Percentile xBA (.269) 🥶 16th Percentile Whiff% 🥶 26th Percentile K%
Wags Wins
Wags Wins
Last 30d: 161-162-0 (-24.8u)
Over 8-105
1.25u
Anthony Dabbundo
Anthony Dabbundo
Last 30d: 38-39-3 (-5.6u)
CLE -125
1u
Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 54-96-11 (-13.7u)
CLE -115
0.87u
@Zerillo ⭐️⭐️⭐️ https://myaction.app/qxJUWRHux3b
Nick Martin
Nick Martin
Last 30d: 21-22-1 (-0.2u)
BOS +110
0.5u
RoyalsProps
RoyalsProps
Last 30d: 57-58-0 (-10.1u)
W.Contreras o1.5 Hits + Runs + RBIs-117
1u
Frank Ammirante
Frank Ammirante
Last 30d: 329-277-11 (+55.5u)
S.Cecconi o15.5 Outs-117
1.17u
CLE -118
1u
Sean Zerillo
Sean Zerillo
Last 30d: 153-129-9 (+4.1u)
CLE -120
0.5u
Bet to -133

Red Sox vs. Guardians Previews & Analysis

  • Red Sox vs Guardians: Zerillo's Pick for Friday article feature image

    Red Sox vs Guardians: Zerillo's Pick for Friday

    Sean Zerillo
    May 29, 2026 UTC
  • Adam Trigger's Triple-A Baseball Bets for Friday article feature image

    Adam Trigger's Triple-A Baseball Bets for Friday

    Adam Trigger
    May 29, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Red Sox vs. Guardians Public Betting Percentages

Away Logo

Red Sox

Public

30%

Bets%

70%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians
42-3719-1723-2018-2324-13
Red Sox
30-4612-2518-2117-3012-16

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians
39-4018-1821-2221-2017-20
Red Sox
33-40-313-22-220-18-120-25-213-14-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians
41-3819-1722-2122-1919-18
Red Sox
31-4512-2519-2019-2811-17

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 27thWSHW 3-2-1.5 LU 7.5CLE -180
May 26thWSHL 3-6-1.5 LO 7.5WSH -133
May 25thWSHL 2-10-1.5 LO 8.5WSH -174
May 24th@PHIW 3-1-1.5 WU 7CLE -115
May 23rd@PHIL 0-3+1.5 LU 7PHI +145

Red Sox vs. Guardians Injury Updates

Red Sox Injuries

  • Tanner Houck
    SP

    Houck is out with arm

    Out

  • Triston Casas
    1B

    Casas is out with knee

    Out

  • Patrick Sandoval
    SP

    Sandoval is out with elbow

    Out

  • Kutter Crawford
    SP

    Crawford is out with wrist

    Out

  • Romy Gonzalez
    1B

    Gonzalez is out with shoulder

    Out

Guardians Injuries

    Red Sox vs. Guardians Box Score
    Red Sox Player Stats
    Projected
    PITCHERPCIPKER
    Tyler Samaniego logoLT.Samaniego, P22124
    Brayan Bello logoRB.Bello, P63750
    HITTERSH-ABRHRRBI
    Jarren Duran logo1J.Duran, LF1-4001
    Ceddanne Rafaela logo2C.Rafaela, CF0-4000
    Wilyer Abreu logo3W.Abreu, RF0-4000
    Willson Contreras logo4W.Contreras, 1B2-4000
    Nick Sogard logo4N.Sogard, PR0-0000
    Nick Sogard logo4N.Sogard, 1B0-0000
    Masataka Yoshida logo5M.Yoshida, DH1-4000
    Mickey Gasper logo6M.Gasper, C2-4100
    Isiah Kiner-Falefa logo7I.Kiner-Falefa, 2B2-4100
    Marcelo Mayer logo8M.Mayer, SS2-4101
    Caleb Durbin logo9C.Durbin, 3B1-4001
    Guardians Player Stats
    Projected
    PITCHERPCIPKER
    Slade Cecconi logoRS.Cecconi, P694.133
    Colin Holderman logoRC.Holderman, P201.110
    Tim Herrin logoLT.Herrin, P110.200
    Shawn Armstrong logoRS.Armstrong, P70.210
    Hunter Gaddis logoRH.Gaddis, P15100
    Cade Smith logoRC.Smith, P13130
    HITTERSH-ABRHRRBI
    Travis Bazzana logo1T.Bazzana, 2B1-4000
    Jose Ramirez logo2J.Ramirez, 3B1-4100
    Chase DeLauter logo3C.DeLauter, RF2-4100
    Rhys Hoskins logo4R.Hoskins, DH1-4101
    Kyle Manzardo logo5K.Manzardo, 1B2-4100
    Angel Martinez logo6A.Martinez, LF1-4001
    Daniel Schneemann logo7D.Schneemann, CF1-3000
    Patrick Bailey logo8P.Bailey, C1-2001
    Brayan Rocchio logo9B.Rocchio, SS0-3000

    Red Sox vs. Guardians Odds Comparison

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    Red Sox at Guardians Team Totals

    MatchupOverUnder
    Red Sox
    31-45
    N/A
    N/A
    Guardians
    41-38
    N/A
    N/A