Reds vs. Guardians Odds & Betting Predictions - May 16, 2026
Reds at Guardians
10:10 pm • CINRStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 4.05 | 6-3 | ||
![]() | 6.05 | 0-2 |
Reds at Guardians Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Reds 37-40 | +1.5 | +1.5-156 | o8.5-109 | +125 |
Guardians 41-38 | u8.5 | -1.5+136 | u8.5-113 | -150 |

Progressive FieldCleveland
Reds vs. Guardians Expert Picks
Wags Wins
Last 30d: 157-146-0 (-8.2u)
CIN +135
1u
YBK Picks.com
Last 30d: 15-12-2 (+2.2u)
CIN +1-110
2u
Derek Carty
Last 30d: 33-36-1 (+18.8u)
C.Paddack o14.5 Outs-105
1u
THE BAT X is forecasting 16.17 pitching outs for Chris Paddack. Oddsmakers are implying 13.64 pitching outs, so I believe there is value here. If you take the over, you'd be projected to win 74% of the time resulting in a 44% ROI with expected value of $46.58 (based on a $100 wager). This play is good down to at least -205.
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Sean Zerillo
Last 30d: 148-125-9 (+4.4u)
Over 8.5-102
0.25u
ONLY if you have Under 8.5. Make this 8 now - taking half off original position
Top Shelf Action 🥃
Last 30d: 7-12-2 (-3.7u)
E.De La Cruz u1.5 Hits + Runs + RBIs+100
0.76u
#EV 6.09%
Alex Hinton
Last 30d: 69-67-1 (+12.3u)
E.De La Cruz o1.5 Total Bases+135
1u
Picks Office
Last 30d: 138-140-13 (-12.9u)
CIN +145
1u
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Cincinnati is 6-4 over its last 10 while Cleveland is 4-6 over the same stretch.
The Reds have scored 50 runs in that window, enough offense to support a plus-money ML without confirmed starters.
Cleveland has allowed 54 runs over its last 10, and this price is too wide for two teams separated by half a game.
Over 4.5 (F5)-120
0.83u
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This is an early-run bet built around Chris Paddack's 7.63 ERA and 1.663 WHIP.
Cleveland has averaged 5.2 runs over the last 10, and Cincinnati games have averaged 9.8 total runs in that same window.
The number only asks for 5 runs before the bullpen phase, with both projected lineups carrying enough top-order pressure to get there.
RoyalsProps
Last 30d: 57-58-0 (-10.1u)
S.Steer o1.5 Hits + Runs + RBIs-105
1u

Sean Zerillo
Last 30d: 148-125-9 (+4.4u)
Under 8.5-110
0.55u
Update: Want -110 to bet and would keep smaller
Brandon Kravitz
Last 30d: 55-49-0 (+10.1u)
Under 8.5-104
1.04u
Frank Ammirante
Last 30d: 320-265-11 (+57.1u)
Over 8-115
1u
Top Shelf Action 🥃
Last 30d: 7-12-2 (-3.7u)
CLE -0.5 (F5)-102
1.32u
#EV 2.59%

Sean Zerillo
Last 30d: 148-125-9 (+4.4u)
CIN +150
0.5u
Bet to +133
Matt Trollo
Last 30d: 74-82-9 (-9.6u)
Under 8.5-115
0.58u
Not including this in Saturday's breakdown because only FD has this price and I'd want 8.5. Negative run environment, neutral weather, G.Williams approaching 30 K%, both offenses below 95 wRC+ Hm/Rd/v RHP, CLE proj Def 13 FRV, 7th best bullpen estimators L30 days
Reds vs. Guardians Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Reds vs. Guardians Public Betting Percentages
Betting Trends
- Guardians are 2-3 in their last 5 games.
- Guardians are 3-2 in their last 5 games against the spread
- Guardians are 23-20 in their road games against the spread
- The totals have gone OVER in 3 of Guardians' last 5 games
- The totals have gone OVER in 18 of Guardians' 36 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Guardians vs. Reds Injury Updates

Guardians Injuries

Reds Injuries
- Hunter GreeneSP
Greene is out with elbow
Out
Reds vs. Guardians Box Score
Reds Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 78 | 5 | 3 | 2 | |
![]() | 21 | 0.1 | 1 | 2 | |
![]() | 22 | 1.1 | 2 | 1 | |
![]() | 12 | 0.1 | 0 | 1 | |
![]() | 27 | 1 | 2 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 1-4 | 1 | 1 | 1 |
![]() | 1-3 | 1 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 1 |
![]() | 1-4 | 0 | 0 | 2 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 2-3 | 1 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-2 | 1 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
Guardians Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 87 | 5 | 4 | 4 | |
![]() | 13 | 1.2 | 1 | 0 | |
![]() | 5 | 0.1 | 1 | 0 | |
![]() | 14 | 1 | 0 | 0 | |
![]() | 17 | 1 | 2 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 1 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 2-4 | 1 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 2-5 | 1 | 0 | 0 |
![]() | 1-5 | 0 | 0 | 0 |
![]() | 1-3 | 2 | 0 | 0 |
![]() | 2-4 | 3 | 1 | 2 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 2-3 | 0 | 0 | 2 |
Reds vs. Guardians Odds Comparison
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Reds at Guardians Team Totals
MatchupOverUnder | ||
|---|---|---|
Reds 37-40 | N/A | N/A |
Guardians 41-38 | N/A | N/A |




































