Duke vs. Louisville Odds & Betting Predictions - January 7, 2026
Duke at Louisville
12:00 am • ESPNDuke at Louisville Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Duke 29-2 | +2.5 | -1.5-105 | o161.5-110 | -112 |
Louisville 22-9 | u160.5 | +1.5-115 | u161.5-112 | -108 |

KFC Yum! CenterLouisville
Duke vs. Louisville Expert Picks
Jeremiah Rose
Last 30d: 8-11-0 (-0.8u)
DUKE +5 (Live)-112
0.18u
Boyd / FanDuel
OldSchool0909
Last 30d: 72-74-3 (-1.3u)
LOU +1.5-116
1u
Wags Wins
Last 30d: 295-268-2 (+23.6u)
Under 162.5-115
1.09u
Nick Giffen
Last 30d: 23-82-0 (+8.9u)
Over 161.5-110
0.28u
Have this at 165.5
Tanner's projections have 165.1
Over it is.
Top Shelf Action 🥃
Last 30d: 165-181-1 (-32.3u)
LOU PK-110
0.5u
#RLM
JMann
Last 30d: 38-27-0 (+10.6u)
Over 162.5-110
1u
Mjaybrod
Last 30d: 60-44-1 (+10.2u)
LOU +114
1u
Boosted
Ryan Minion
Last 30d: 202-221-2 (+48.1u)
R.Conwell o19.5 Pts-130
$1.00
LOU +1.5-110
$1.10
The Pick Don
Last 30d: 11-7-0 (+3.3u)
LOU -110
1.1u
Stuck 🚨
Last 30d: 49-54-3 (-0.3u)
LOU +1-110
0.3u
Mike McNamara
Last 30d: 99-109-1 (+2.7u)
LOU -110
0.28u
Anders
Last 30d: 9-10-0 (-3.8u)
LOU +1.5-110
1.1u
Analysis in Twitter Vid
Boomer Betz
Last 30d: 101-85-6 (+24.3u)
DUKE +2.5-120
$100.00
Duke vs. Louisville Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Duke vs. Louisville Public Betting Percentages
Betting Trends
- Louisville are 3-2 in their last 5 games.
- Louisville are 2-3 in their last 5 games against the spread
- Louisville are 6-8 in their road games against the spread
- The totals have gone OVER in 2 of Louisville' last 5 games
- The totals have gone OVER in 5 of Louisville' 17 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 15-16 | 9-8 | 6-8 | 11-11 | 1-3 | |
| 18-13 | 10-10 | 8-3 | 14-11 | 1-0 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 12-19 | 5-12 | 7-7 | 9-13 | 1-3 | |
| 10-21 | 6-14 | 4-7 | 8-17 | 0-1 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 22-9 | N/A | N/A | 16-6 | 1-3 | |
| 29-2 | N/A | N/A | 23-2 | 1-0 |
Last 5 Matchups
Louisville vs. Duke Injury Updates

Louisville Injuries
- Kasean PryorF
Pryor is questionable with undisclosed
Questionable
- Mikel BrownG
Brown is questionable with back
Questionable

Duke Injuries
- Ifeanyi UfochukwuC
Ufochukwu is questionable with undisclosed
Questionable
- Caleb FosterG
Foster is injured with foot
Out Indefinitely
- Patrick NgongbaC
Ngongba is injured with undisclosed
Out Indefinitely
Team Stats
29-57 (51%)
Field Goals
26-65 (40%)
19-28 (68%)
Free Throws
9-12 (75%)
7-23 (30%)
3P
12-38 (32%)
36
Rebounds
37
9
Assists
13
12
Turnovers
14
11
Steals
7
2
Blocks
1
17
Fouls
20
Duke vs. Louisville Odds Comparison
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Duke at Louisville Team Totals
MatchupOverUnder | ||
|---|---|---|
Duke 29-2 | N/A | N/A |
Louisville 22-9 | N/A | N/A |



