E. Michigan vs. Buffalo Odds & Betting Predictions - October 4, 2025

E. Michigan at Buffalo

7:30 pm • ESPN+
30 - 31

E. Michigan at Buffalo Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
E. Michigan
2-6
+9.5
+9.5-110
o53.5-110
+265
Buffalo
4-3
u48.5
-9.5-110
u53.5-110
-330
location pinSaturday 7:30 p.m.
October 04, 2025
UB StadiumBuffalo
E. Michigan vs. Buffalo Expert Picks
Picks Office
Picks Office
Last 30d: 91-77-3 (+8.5u)
Over 54.5-110
0.91u
BBOC G5 Deep Dive Pod
BBOC G5 Deep Dive Pod
Last 30d: 14-22-0 (-6.9u)
Under 54.5-108
1u
Mike Calabrese
Mike Calabrese
Last 30d: 29-40-0 (-7.7u)
Under 54.5-105
1.75u
Ta’Quan Roberson is out of his boot, but this Buffalo offense is still pretty flat even with him at full strength. He just isnt consistent through the air and his playcaller, Dave Patenaude, has the running game to beat EMU. What’s weird about Roberson is his aDOT is really high 11.6 (10th nationally), but his yards per attempt is just 7.0. That’s because he can’t connect downfield. Passes 10 to 19 yards downfield (2-for-9), 20+ yards downfield (9-for-24). That’s a completion percentage of 33% when he pushes it beyond ten yards. I still like this Buffalo defense, just as I did in the preseason. They’re solid across the board, but they have a great pass rush. They’ve gotten home 17 times this year (4th most). And Eastern Michigan has been dreadful in passing down situations, 100th in success rate there. THe last game against CMU for EMU, I think will be closer to what we see on Saturday. It was 24-13 CMU, but after the first 20 minutes, EMU held them to 3 points for the rest of the game. I see them mucking this one up as well.
Babs .
Babs .
Last 30d: 90-95-3 (-0.8u)
EMU u21.5 Team Total-120
1u

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Prop Odds Comparison

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Line Movement Tracker

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E. Michigan vs. Buffalo Public Betting Percentages

Away Logo

E. Michigan

Public

54%

Bets%

46%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Buffalo
2-51-31-20-41-1
E. Michigan
4-42-12-30-14-3

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Buffalo
4-32-22-13-10-2
E. Michigan
5-31-24-10-15-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Buffalo
4-3N/AN/A3-10-2
E. Michigan
2-6N/AN/A0-12-5

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 27thUCONNL 17-20+2.5 LU 50.5UCONN +125
Sep 20thTROYL 17-21-5.5 LU 43.5TROY -220
Sep 13th@KENTW 31-28-23.5 LO 48.5BUFF -2100
Sep 6thSTFW 45-6-37.5 WO 48.5-
Aug 29th@MINNL 10-23+16.5 WU 42.5MINN +575
Team Stats
395
Total Yards
387
85
Total Plays
70
4.647058823529412
Yards Per Play
5.5285714285714285
168
YDS
272
19/31
Comps/Atts
19/39
5.419354838709677
YPA
6.9743589743589745
2/0
TDs/INTs
3/0
0/0
Sacks/Yards
3/14
227
Rush Yards
115
54
Attempts
31
4.203703703703703
YPC
3.7096774193548385
2
TDs
1
0
Fumbles Lost
1
0
Interceptions
0
3/3 100%
Redzone
3/4 75%
8/20 0%
3rd Down
7/15 0%
2/2 0%
4th Down
0/1 0%
25
Total
21
8
Pass
10
13
Rush
8
4
Penalty
3
9/80
Penalties/Yards
6/69

E. Michigan vs. Buffalo Odds Comparison

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E. Michigan at Buffalo Team Totals

MatchupOverUnder
E. Michigan
2-6
o21.5-106
u21.5-120
Buffalo
4-3
o31.5-104
u31.5-128