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S. Carolina vs. Missouri Odds & Betting Predictions - September 20, 2025

S. Carolina at Missouri

11:00 pm • ESPN

South Carolina Gamecocks

3-5
20
20 - 29

Missouri Tigers

6-2
29

S. Carolina at Missouri Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
S. Carolina
3-5
+3.5
+10-110
o48.5-110
+280
Missouri
6-2
u48.5
-10-110
u48.5-110
-350
location pinSaturday 11:00 p.m.
September 20, 2025
Memorial Stadium/Faurot FieldColumbia
S. Carolina vs. Missouri Expert Picks
Will Brinson
Will Brinson
Last 30d: 17-20-1 (-3.3u)
MIZ -6.5 (2H)-110
1u
Boomer Betz
Boomer Betz
Last 30d: 169-160-3 (+12.8u)
SC +11.5 (Live)-115
0.87u
Sean Zerillo
Sean Zerillo
Last 30d: 102-128-5 (+1.8u)
SC +10-110
0.25u
Sandy Plashkes
Sandy Plashkes
Last 30d: 95-104-2 (-3.7u)
SC +10.5-114
1u
Picks Office
Picks Office
Last 30d: 108-91-3 (+10.7u)
SC +10-105
0.95u
Mjaybrod
Mjaybrod
Last 30d: 84-109-1 (-18.1u)
MIZ u29.5 Team Total-110
0.91u
Backing some cock defense on a Saturday
Dan Gaspar
Dan Gaspar
Last 30d: 43-45-3 (-7.5u)
D.Murph u31.5 Rec Yds-115
1.15u
N.Harbor u60.5 Rec Yds-114
1u

S. Carolina vs. Missouri Previews & Analysis

  • Our NCAAF Best Bets for Saturday Night article feature image

    Our NCAAF Best Bets for Saturday Night

    Action Network Staff•
    Sep 20, 2025 UTC
  • South Carolina vs. Missouri: The Battle of the Columbias article feature image

    South Carolina vs. Missouri: The Battle of the Columbias

    Greg Liodice•
    Sep 20, 2025 UTC
  • Your Week 4 NCAAF Betting Cheat Sheet article feature image

    Your Week 4 NCAAF Betting Cheat Sheet

    Pete Ruden•
    Sep 20, 2025 UTC
  • Our Top NCAAF Props for Week 4 article feature image

    Our Top NCAAF Props for Week 4

    Doug Ziefel•
    Sep 20, 2025 UTC
See more NCAAF Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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S. Carolina vs. Missouri Public Betting Percentages

Away Logo

S. Carolina

Public

Home Logo

Missouri

95%

Bets%

5%

Money%

NCAAF Public Betting Right Arrow

Betting Trends

  • Missouri are 5-0 in their last 5 games.
  • Missouri are 4-1 in their last 5 games against the spread
  • Missouri are 1-1 in their road games against the spread
  • The totals have gone OVER in 4 of Missouri' last 5 games
  • The totals have gone OVER in 4 of Missouri' 6 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Missouri		4-3-13-2-11-13-10-1-1
S. Carolina		4-42-31-12-12-2

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Missouri		4-44-20-23-10-2
S. Carolina		3-52-31-11-22-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Missouri		6-2N/AN/A4-00-2
S. Carolina		3-5N/AN/A2-10-4

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 13thULW 52-10-27.5 WO 47.5MIZ -5000
Sep 6thKUW 42-31-5.5 WO 50.5MIZ -205
Aug 28thCARKW 61-6-38.5 WO 53.5-
Dec 30thIOWAW 27-24-1.5 WO 41.5MIZ -115
Nov 30thARKW 28-21-3 WU 51MIZ -144
Team Stats

Total

293
Total Yards
456
50
Total Plays
75
5.86
Yards Per Play
6.08

Passing

302
YDS
171
18/28
Comps/Atts
16/27
10.785714285714286
YPA
6.333333333333333
2/0
TDs/INTs
1/1
5/46
Sacks/Yards
1/5

Rushing

-9
Rush Yards
285
22
Attempts
48
-0.4090909090909091
YPC
5.9375
0
TDs
2

Turnovers

0
Fumbles Lost
0
0
Interceptions
1

Efficiency

2/2 100%
Redzone
6/6 100%
3/11 0%
3rd Down
7/13 0%
0/1 0%
4th Down
0/0 0%

First Downs

15
Total
29
11
Pass
10
1
Rush
15
3
Penalty
4

Misc

14/98
Penalties/Yards
5/54

S. Carolina vs. Missouri Odds Comparison

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S. Carolina at Missouri Team Totals

MatchupOverUnder
S. Carolina
3-5
o19.5-113
u19.5-116
Missouri
6-2
o29.5-118
u29.5-109