Syracuse vs. Notre Dame Odds & Betting Predictions - November 22, 2025
Syracuse at Notre Dame
8:30 pm • NBCSyracuse at Notre Dame Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Syracuse 3-8 | +36.5 | +36.5-110 | o51-115 | N/A |
 Notre Dame 9-2 | u51.5 | -36.5-110 | u51-110 | N/A |
Notre Dame StadiumSouth Bend
Syracuse vs. Notre Dame Expert Picks
Sandy Plashkes
Last 30d: 121-141-7 (-25.8u)
W.Pauling o33.5 Rec Yds-112
1.68u
Stuck 🚨
Last 30d: 50-55-1 (-2.4u)
ND -35.5-110
0.27u
Speculating Irish wanna run it up here. Plus Cuse starting lax bro. Might come back if ND takes ton of money like every week or live.
Syracuse vs. Notre Dame Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Syracuse vs. Notre Dame Public Betting Percentages
Betting Trends
- Notre Dame are 4-1 in their last 5 games.
- Notre Dame are 4-1 in their last 5 games against the spread
- Notre Dame are 2-2 in their road games against the spread
- The totals have gone OVER in 4 of Notre Dame' last 5 games
- The totals have gone OVER in 4 of Notre Dame' 7 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 6-5 | 4-3 | 2-2 | 5-5 | N/A |
| 4-6-1 | 1-3-1 | 3-2 | 0-1-1 | 3-4 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 6-5 | 4-3 | 2-2 | 5-5 | N/A |
| 6-5 | 1-4 | 4-1 | 0-2 | 4-3 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 9-2 | N/A | N/A | 8-2 | N/A |
| 3-8 | N/A | N/A | 1-1 | 1-6 |
Last 5 Matchups
Team Stats
95
YDS
67
17/30
Comps/Atts
9/15
3.1666666666666665
YPA
4.466666666666667
0/3
TDs/INTs
1/0
5/24
Sacks/Yards
1/10
5/39
Penalties/Yards
5/55
Syracuse vs. Notre Dame Odds Comparison
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Syracuse at Notre Dame Team Totals
MatchupOverUnder | ||
|---|---|---|
Syracuse 3-8 | o6.5-138 | u6.5-115 |
Notre Dame 9-2 | o43.5-118 | u43.5-114 |