Saints vs. Seahawks Odds & Betting Predictions - September 21, 2025

Saints at Seahawks

8:05 pm • CBS
13 - 44

Saints at Seahawks Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Saints
0-4
+6.5
+7.5-118
o41.5-111
+310
Seahawks
3-1
u43.5
-7.5-102
u41.5-110
-390
location pinSunday 8:05 p.m.
September 21, 2025
Lumen FieldSeattle
Saints vs. Seahawks Expert Picks
Sean Koerner
Sean Koerner
Last 30d: 29-39-0 (-4.1u)
G.Holani o16.5 Rush Yds-120
0.5u
Holani should take over most of the Charbs role, but I do expect them to lean even more on KW3. Still, he’s popping in our prop tool because some sites are offering props on him now, this number is too low (would proj his median closer to 24.5 or so). I’m +23 vs ECR on FantasyPros and think the market in general is overlooking him here.
Mjaybrod
Mjaybrod
Last 30d: 68-85-3 (-11.6u)
Under 42-110
1u
Nasty stinker
Matthew Freedman
Matthew Freedman
Last 30d: 30-37-0 (-5.9u)
NO +7.5-115
1.15u
Projection: +7. For more, check out the Fantasy Life game model.
S.Darnold o0.5 Int+110
1u
Projection: -155. For more, check out the Fantasy Life player projections.
R.Shaheed Anytime TD Scorer Yes+365
0.5u
Projection: +330. For more, check out the Fantasy Life player projections.
The Propfessor
The Propfessor
Last 30d: 34-56-2 (+1.2u)
A.Kamara o3.5 Recs-140
1u
Matt DiLeo
Matt DiLeo
Last 30d: 44-29-0 (+7.8u)
A.Kamara o3.5 Recs-132
1u
Allan Lem
Allan Lem
Last 30d: 116-116-7 (-5.9u)
K.Walker u19.5 Rush Att-110
0.5u
Tailing @chrisgimino_. RG projections have him closer to 15.5 rush attempts assuming we don’t see Walker be a complete bell cow with Zach Charbonnet doubtful, which I tend to agree with.
Chris Gimino
Chris Gimino
Last 30d: 30-28-0 (+8.8u)
G.Holani o4.5 Rush Att+100
2u
K.Walker u19.5 Rush Att-110
0.91u
💰🦡 Jake
💰🦡 Jake
Last 30d: 102-118-7 (+35.7u)
Over 41.5-108
1u
Markus Markets
Markus Markets
Last 30d: 32-26-2 (+9.9u)
A.Kamara o3.5 Recs-127
1u
Moneyline Hacks
Moneyline Hacks
Last 30d: 107-131-8 (+40.4u)
S.Rattler o14.5 Rush Yds-108
1u
🔥Fade the Noise Podcast Ep. 18 LIVE NOW! 🎙️ https://www.youtube.com/@FadetheNoise We break down all the biggest bets of the weekend: 🥊 UFC Noche Recap 🏈 NFL Best Bets 🗣️ Join our Discord community of over 4000 members: https://discord.gg/A8v49URQaG Podcast also available on Spotify. Tap in & Fade the Noise with us. 📈💰
Gilles Gallant
Gilles Gallant
Last 30d: 22-65-0 (-6.5u)
J.Johnson Anytime TD Scorer Yes+370
1u
ThatGuyBets
ThatGuyBets
Last 30d: 6-5-0 (+0.5u)
K.Walker o52.5 Rush Yds-114
1u
Cam Is Money
Cam Is Money
Last 30d: 53-68-3 (-13.8u)
NO +7.5-115
1u
A.Kamara o3.5 Recs-125
1u
Royals Props
Royals Props
Last 30d: 22-23-1 (-4.7u)
A.Kamara o3.5 Recs-118
1.18u
FD
Action Pod NFL Picks
Action Pod NFL Picks
Last 30d: 44-97-0 (-19.8u)
Under 41.5-110
1u
@Stuckey2 Favorite Total https://myaction.app/InPuWjTELWb
Ryan Sura
Ryan Sura
Last 30d: 100-92-2 (+8.6u)
K.Walker o53.5 Rush Yds-115
1.15u
Moneyline Hacks
Moneyline Hacks
Last 30d: 107-131-8 (+40.4u)
Z.Charbonnet Anytime TD Scorer Yes+3300
0.5u
🚨Free analysis & VIP Picks can be found on our Discord. Link: https://discord.gg/A8v49URQaG 🎙️Fade the Noise PODCAST - Subscribe!✅ https://www.youtube.com/@FadetheNoise 🔥70% OFF VIP!! ⬇️⬇️ (COPY & PASTE LINK): https://dubclub.win/r/p/pri-jnydr/?checkout=1&coupon=BookieHacks70
C.Kupp Anytime TD Scorer Yes+1400
0.5u
🚨Free analysis & VIP Picks can be found on our Discord. Link: https://discord.gg/A8v49URQaG 🎙️Fade the Noise PODCAST - Subscribe!✅ https://www.youtube.com/@FadetheNoise 🔥70% OFF VIP!! ⬇️⬇️ (COPY & PASTE LINK): https://dubclub.win/r/p/pri-jnydr/?checkout=1&coupon=BookieHacks70
RocketPlays
RocketPlays
Last 30d: 22-28-0 (+9.9u)
J.Smith-Njigba o66.5 Rec Yds-110
0.91u
Greg Matherne
Greg Matherne
Last 30d: 27-36-1 (+5.6u)
NO +7.5-110
0.55u
Jim Sannes
Jim Sannes
Last 30d: 15-52-0 (-12.9u)
NO +7+100
1u
Underlying numbers on New Orleans kinda don't suck so far, and getting +7 at even money in a potential low-scoring game is pretty attractive.
Boomer Betz
Boomer Betz
Last 30d: 130-100-2 (+44.2u)
NO +7.5-101
1u
Matt Moore
Matt Moore
Last 30d: 14-15-1 (-2.0u)
NO +7+100
1.1u
FTN Fantasy
FTN Fantasy
Last 30d: 79-91-1 (-20.0u)
SEA -7.5-105
0.95u

Saints vs. Seahawks Previews & Analysis

  • Saints vs. Seahawks: Stuckey's Pick for NFL Week 3 article feature image

    Saints vs. Seahawks: Stuckey's Pick for NFL Week 3

    Stuckey
    Sep 21, 2025 UTC
  • Anytime Touchdown Picks for Every NFL Game article feature image

    Anytime Touchdown Picks for Every NFL Game

    Gilles Gallant
    Sep 21, 2025 UTC
  • A 50-1 TD Pick Leads Best Late-Slate Bets article feature image

    A 50-1 TD Pick Leads Best Late-Slate Bets

    Alex Kolodziej
    Sep 21, 2025 UTC
  • 14-1, 9-1 Sleepers Lead Top ATD Edges  article feature image

    14-1, 9-1 Sleepers Lead Top ATD Edges

    Alex Kolodziej
    Sep 21, 2025 UTC
See more NFL Coverage Right Arrow

Saints vs. Seahawks Props

Prop Projections

See All
Right Arrow

There are no prop projections found for the selected slate. Please check back later.

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

Saints vs. Seahawks Public Betting Percentages

Away Logo

Saints

Public

41%

Bets%

59%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Seahawks
3-11-12-02-01-1
Saints
1-30-21-1N/A1-3

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Seahawks
2-21-11-11-11-1
Saints
3-11-12-0N/A3-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Seahawks
3-1N/AN/A2-01-1
Saints
0-4N/AN/AN/A0-4

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 14th@PITW 31-17+3.5 WO 40.5SEA +154
Sep 7thSFL 13-17+2.5 LU 43.5SF +112
Aug 23rd@GBL 7-20+3 LU 37.5GB +140
Aug 16thKCW 33-16-5 WO 38SEA -220
Aug 8thLVW 23-23+5.5 WO 36.5LV +200

Saints vs. Seahawks Injury Updates

Saints Injuries

  • Taysom Hill
    TE

    Hill is out with knee

    Out

  • Chase Young
    DE

    Young is out with calf

    Out

  • Trevor Penning
    OL

    Penning is out with toe

    Out

  • Jordan Howden
    DB

    Howden is questionable with oblique

    Questionable

Seahawks Injuries

  • Uchenna Nwosu
    LB

    Nwosu is out with knee

    Out

Team Stats
284
Total Yards
320
70
Total Plays
54
4.1
Yards Per Play
5.9
218
YDS
233
28/41
Comps/Atts
16/21
4.767
YPA
11.095
1/1
TDs/INTs
2/0
2/13
Sacks/Yards
0/0
79
Rush Yards
87
27
Attempts
33
2.926
YPC
2.636
0
TDs
2
0
Fumbles Lost
1
1
Interceptions
0

Efficiency

1/3 33.33%
Redzone
4/5 80%
5/15 0%
3rd Down
3/9 0%
0/2 0%
4th Down
0/0 0%

First Downs

21
Total
22
12
Pass
11
4
Rush
7
5
Penalty
4
11/77
Penalties/Yards
8/70
32:16
Possession
27:44

Saints vs. Seahawks Odds Comparison

Right Arrow

Could not load odds

Saints at Seahawks Team Totals

MatchupOverUnder
Saints
0-4
o16.5-128
u16.5+103
Seahawks
3-1
o24.5-110
u24.5-112