Saints vs. Seahawks Odds & Betting Predictions - September 21, 2025
Saints at Seahawks
8:05 pm • CBSSaints at Seahawks Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Saints 0-4 | +6.5 | +7.5-118 | o41.5-111 | +310 |
![]() Seahawks 3-1 | u43.5 | -7.5-102 | u41.5-110 | -390 |

Lumen FieldSeattle
Saints vs. Seahawks Expert Picks

Sean Koerner
Last 30d: 29-39-0 (-4.1u)
G.Holani o16.5 Rush Yds-120
0.5u
Holani should take over most of the Charbs role, but I do expect them to lean even more on KW3. Still, he’s popping in our prop tool because some sites are offering props on him now, this number is too low (would proj his median closer to 24.5 or so). I’m +23 vs ECR on FantasyPros and think the market in general is overlooking him here.

Mjaybrod
Last 30d: 68-85-3 (-11.6u)
Under 42-110
1u
Nasty stinker

Matthew Freedman
Last 30d: 30-37-0 (-5.9u)
NO +7.5-115
1.15u
Projection: +7. For more, check out the Fantasy Life game model.
S.Darnold o0.5 Int+110
1u
Projection: -155. For more, check out the Fantasy Life player projections.
R.Shaheed Anytime TD Scorer Yes+365
0.5u
Projection: +330. For more, check out the Fantasy Life player projections.

The Propfessor
Last 30d: 34-56-2 (+1.2u)
A.Kamara o3.5 Recs-140
1u

Matt DiLeo
Last 30d: 44-29-0 (+7.8u)
A.Kamara o3.5 Recs-132
1u

Allan Lem
Last 30d: 116-116-7 (-5.9u)
K.Walker u19.5 Rush Att-110
0.5u
Tailing @chrisgimino_. RG projections have him closer to 15.5 rush attempts assuming we don’t see Walker be a complete bell cow with Zach Charbonnet doubtful, which I tend to agree with.

Chris Gimino
Last 30d: 30-28-0 (+8.8u)
G.Holani o4.5 Rush Att+100
2u
K.Walker u19.5 Rush Att-110
0.91u

💰🦡 Jake
Last 30d: 102-118-7 (+35.7u)
Over 41.5-108
1u

Markus Markets
Last 30d: 32-26-2 (+9.9u)
A.Kamara o3.5 Recs-127
1u

Moneyline Hacks
Last 30d: 107-131-8 (+40.4u)
S.Rattler o14.5 Rush Yds-108
1u
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Gilles Gallant
Last 30d: 22-65-0 (-6.5u)
J.Johnson Anytime TD Scorer Yes+370
1u

ThatGuyBets
Last 30d: 6-5-0 (+0.5u)
K.Walker o52.5 Rush Yds-114
1u

Cam Is Money
Last 30d: 53-68-3 (-13.8u)
NO +7.5-115
1u
A.Kamara o3.5 Recs-125
1u

Royals Props
Last 30d: 22-23-1 (-4.7u)
A.Kamara o3.5 Recs-118
1.18u
FD

Action Pod NFL Picks
Last 30d: 44-97-0 (-19.8u)
Under 41.5-110
1u
@Stuckey2 Favorite Total https://myaction.app/InPuWjTELWb

Ryan Sura
Last 30d: 100-92-2 (+8.6u)
K.Walker o53.5 Rush Yds-115
1.15u

Moneyline Hacks
Last 30d: 107-131-8 (+40.4u)
Z.Charbonnet Anytime TD Scorer Yes+3300
0.5u
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C.Kupp Anytime TD Scorer Yes+1400
0.5u
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RocketPlays
Last 30d: 22-28-0 (+9.9u)
J.Smith-Njigba o66.5 Rec Yds-110
0.91u

Greg Matherne
Last 30d: 27-36-1 (+5.6u)
NO +7.5-110
0.55u

Jim Sannes
Last 30d: 15-52-0 (-12.9u)
NO +7+100
1u
Underlying numbers on New Orleans kinda don't suck so far, and getting +7 at even money in a potential low-scoring game is pretty attractive.

Boomer Betz
Last 30d: 130-100-2 (+44.2u)
NO +7.5-101
1u

Matt Moore
Last 30d: 14-15-1 (-2.0u)
NO +7+100
1.1u

FTN Fantasy
Last 30d: 79-91-1 (-20.0u)
SEA -7.5-105
0.95u
Saints vs. Seahawks Previews & Analysis
Saints vs. Seahawks Props
Prop Projections
There are no prop projections found for the selected slate. Please check back later.
Prop Odds Comparison
Line Movement Tracker
Saints vs. Seahawks Public Betting Percentages
Betting Trends
- Seahawks are 3-1 in their last 5 games.
- Seahawks are 3-1 in their last 5 games against the spread
- Seahawks are 2-0 in their road games against the spread
- The totals have gone OVER in 2 of Seahawks' last 4 games
- The totals have gone OVER in 1 of Seahawks' 2 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Saints vs. Seahawks Injury Updates

Saints Injuries
- Taysom HillTE
Hill is out with knee
Out
- Chase YoungDE
Young is out with calf
Out
- Trevor PenningOL
Penning is out with toe
Out
- Jordan HowdenDB
Howden is questionable with oblique
Questionable

Seahawks Injuries
- Uchenna NwosuLB
Nwosu is out with knee
Out
Team Stats
Saints vs. Seahawks Odds Comparison
Could not load odds
Saints at Seahawks Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Saints 0-4 | o16.5-128 | u16.5+103 |
![]() Seahawks 3-1 | o24.5-110 | u24.5-112 |