Saints vs. Seahawks Odds & Betting Predictions - September 21, 2025

Saints at Seahawks

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Saints at Seahawks Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Saints
0-0
N/A
N/A
+225
Seahawks
0-0
N/A
N/A
-285
location pinSunday 8:05 p.m.
September 21, 2025
Lumen FieldSeattle

Saints vs. Seahawks Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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Saints vs. Seahawks Public Betting Percentages

Away Logo

Saints

Public

50%

Bets%

50%

Money%

NFL Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Seahawks
N/AN/AN/AN/AN/A
Saints
N/AN/AN/AN/AN/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Seahawks
N/AN/AN/AN/AN/A
Saints
N/AN/AN/AN/AN/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Seahawks
N/AN/AN/AN/AN/A
Saints
N/AN/AN/AN/AN/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Aug 23rd@GBL 7-20+3 LU 37.5GB +140
Aug 16thKCW 33-16-5 WO 38SEA -220
Aug 8thLVW 23-23+5.5 WO 36.5LV +200
Jan 5th@LAW 30-25-7.5 LO 38.5SEA -350
Dec 27th@CHIW 6-3-4.5 LU 42.5SEA -225

Saints vs. Seahawks Injury Updates

Saints Injuries

  • Taysom Hill
    TE

    Hill is out with knee

    Out

  • Chase Young
    DE

    Young is out with calf

    Out

  • Trevor Penning
    OL

    Penning is out with toe

    Out

  • Jordan Howden
    DB

    Howden is questionable with oblique

    Questionable

Seahawks Injuries

  • Dareke Young
    WR

    Young is out with hamstring

    Out

  • Jake Bobo
    WR

    Bobo is out with concussion

    Out

Depth Charts
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Starter2ND3RD4TH
QBSam DarnoldDrew LockJalen Milroe
RBKenneth WalkerZach CharbonnetGeorge HolaniDamien MartinezJacardia Wright
WRCooper KuppDareke Young
TEAJ BarnerElijah ArroyoEric SaubertNick Kallerup
LTCharles CrossAmari Kight
LGGrey ZabelBryce Cabeldue
COlu OluwatimiJalen SundellFederico Maranges
RGAnthony BradfordChristian HaynesMason Richman
RTAbraham LucasJosh Jones
LDEDeMarcus LawrenceDerick HallJared IveyConnor O'Toole
RDELeonard WilliamsMike MorrisJ.R. Singleton
WLBTyrice KnightPatrick O'ConnellJamie Sheriff
MLBErnest JonesDrake Thomas
LCBJosh JobeNehemiah PritchettShemar Jean-Charles
SSJulian LoveNick EmmanworiJerrick Reed
FSCoby BryantD'Anthony BellTy Okada
RCBRiq WoolenShaquill Griffin
PMichael Dickson
HMichael Dickson
PRTory Horton
KRTory HortonZach Charbonnet
LSChris Stoll
NBDevon Witherspoon
LOLBUchenna NwosuBoye Mafe
NTByron MurphyJohnathan HankinsBrandon PiliQuinton Bohanna
KJason Myers
FBRobbie OuztsBrady Russell
DTJarran ReedRylie Mills
LWRJaxon Smith-NjigbaJake BoboCody WhiteTyrone Broden
RWRTory HortonRicky White
ROLBJamie SheriffConnor O'Toole

Saints vs. Seahawks Odds Comparison

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Saints at Seahawks Team Totals

MatchupOverUnder
Saints
0-0
N/A
N/A
Seahawks
0-0
N/A
N/A