Texans vs. Jaguars Odds & Betting Predictions - September 21, 2025

Texans at Jaguars

5:00 pm • CBS

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Houston Texans

0-2

Jacksonville Jaguars

1-1

MatchupOpenSpreadTotalMoneyline
Texans 0-2	-1.5	+1.5-111	o44.5-105	+101
Jaguars 1-1	u46.5	-1.5-109	u44.5-110	-120

Sunday 5:00 p.m.

September 21, 2025

EverBank StadiumJacksonville

84°Fahrenheit

18%Rain

13Wind

HOU +1-105

1.1u

HOU +102

I have the Texans favored by 1.7 in this game. Still skeptical of the Jags, who didn't cover in Week 2 despite having Joe Burrow miss most of the game.

HOU +1.5-110

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NFL Public Betting

Jaguars are 1-1 in their last 5 games.
Jaguars are 1-1 in their last 5 games against the spread
Jaguars are 0-1 in their road games against the spread
The totals have gone OVER in 1 of Jaguars' last 2 games
The totals have gone OVER in 0 of Jaguars' 1 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Jaguars	1-1	1-0	0-1	1-0	0-1
Texans	0-2	0-1	0-1	0-1	0-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Jaguars	1-1	0-1	1-0	0-1	1-0
Texans	0-2	0-1	0-1	0-1	0-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Jaguars	1-1	N/A	N/A	1-0	0-1
Texans	0-2	N/A	N/A	0-1	0-1

date	opponent	score	spread	over/under	moneyline
Sep 14th	@CIN	L 27-31	+3.5 L	O 49.5	CIN +155
Sep 7th	CAR	W 26-10	-4.5 W	U 45.5	JAC -220
Aug 23rd	@MIA	L 6-14	+7 L	U 39.5	MIA +240
Aug 17th	@NO	L 17-17	-2.5 L	U 40.5	NO -132
Aug 9th	PIT	L 25-31	-6 L	O 38.5	PIT -241

Cole Van Lanen
OL
Van Lanen is questionable with shoulder
Questionable

Montaric Brown
CB
Brown is out with ankle
Out
Wyatt Milum
OL
Milum is out with knee
Out

Joe Mixon
RB
Mixon is out with knee
Out
Christian Kirk
WR
Kirk is questionable with hamstring
Questionable
Braxton Berrios
WR
Berrios is out with hamstring
Out
Ed Ingram
G
Ingram is questionable with abdomen
Questionable
Tank Dell
WR
Dell is out with knee
Out
Cade Stover
TE
Stover is out with foot
Out

See more NFL Injuries

passing yards
Trevor Lawrence
449
pyds
passing touchdowns
Trevor Lawrence
4
ptd
rushing yards
Travis Etienne
214
ryds
rushing touchdowns
Brian Thomas
1
rtd

	Starter	2ND	3RD	4TH
QB	Trevor Lawrence	Nick Mullens	Seth Henigan
RB	Travis Etienne	Bhayshul Tuten	LeQuint Allen	Ja'Quinden Jackson
WR	Travis Hunter	Austin Trammell
TE	Brenton Strange	Johnny Mundt	Hunter Long	Quintin Morris	Patrick Herbert
LT	Walker Little
LG	Ezra Cleveland	Wyatt Milum
C	Robert Hainsey	Jonah Monheim	Jerome Carvin
RG	Patrick Mekari	Chuma Edoga	Sal Wormley
RT	Anton Harrison	Cole Van Lanen	Ricky Lee
LDE	Travon Walker	Emmanuel Ogbah	B.J. Green
RDE	Josh Hines-Allen	Dawuane Smoot	Danny Striggow
WLB	Foyesade Oluokun	Jack Kiser
MLB	Devin Lloyd	Ventrell Miller	Branson Combs
LCB	Jarrian Jones	Travis Hunter	Keni-H Lovely
SS	Eric Murray	Antonio Johnson	Rayuan Lane
FS	Andrew Wingard	Darnell Savage	Caleb Ransaw	Cam'Ron Silmon-Craig
RCB	Tyson Campbell	Montaric Brown
P	Logan Cooke
H	Logan Cooke
PR	Parker Washington	Austin Trammell
KR	Parker Washington	Austin Trammell
LS	Ross Matiscik
NT	DaVon Hamilton	Austin Johnson
LWR	Brian Thomas	Parker Washington
ROLB	Dennis Gardeck	Jalen McLeod	Yasir Abdullah
NB	Jourdan Lewis	Christian Braswell	Jabbar Muhammad
RWR	Dyami Brown	Chandler Brayboy
K	Cam Little
DT	Arik Armstead	Maason Smith	Khalen Saunders	Keivie Rose