Bruins vs. Sabres Odds & Betting Predictions - April 21, 2026

Bruins at Sabres

11:30 pm • ESPN

Boston Bruins

4

4 - 2

Buffalo Sabres

2

MatchupOpenSpreadTotalMoneyline
Bruins 1-1	+1.5	+1.5-181	o6.5-103	+137
Sabres 1-1	u6	-1.5+151	u6.5-118	-165

location pin

Tuesday 11:30 p.m.

April 21, 2026

KeyBank CenterBuffalo

BUF +135 (Live)

1u

Under 6-105

1.05u

Under 6.5-133

0.75u

BOS +145

$1.45

BOS +155

1.55u

Our NHL System Pick for Bruins vs Sabres
Action Network Staff•
Apr 21, 2026 UTC

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No props found

NHL Public Betting

Sabres are 1-1 in their last 5 games.
Sabres are 0-2 in their last 5 games against the spread
Sabres are 26-15 in their road games against the spread
The totals have gone OVER in 1 of Sabres' last 2 games
The totals have gone OVER in 1 of Sabres' 2 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Sabres	0-2	0-2	26-15	0-2	28-10
Bruins	2-0	27-14	2-0	12-16	2-0

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Sabres	1-1	1-1	19-22	1-1	16-22
Bruins	1-1	19-22	1-1	12-16	1-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Sabres	1-1	N/A	24-17	1-1	23-15
Bruins	1-1	29-12	N/A	18-10	1-1

date	opponent	score	spread	over/under	moneyline
Apr 19th	BOS	W 4-3	-1.5 L	O 6.5	BUF -166
Apr 15th	DAL	L 3-4	+1.5 W	O 6.5	DAL +124
Apr 14th	@CHI	W 5-1	-1.5 W	U 6.5	BUF -219
Apr 9th	CBJ	W 5-0	-1.5 W	U 6.5	BUF -105
Apr 8th	@NYR	W 5-3	-1.5 W	O 6.5	BUF -135

Sam Carrick
C
Carrick is out with arm
Out
Justin Danforth
RW
Danforth is out for season with knee
Out for Season
Noah Ostlund
C
Ostlund is day-to-day with upper body
Day-to-Day
Jiri Kulich
C
Kulich is out for season with ear
Out for Season

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4

Goals

2

8

Assists

4

14

Penalties

14

26

Shots

34

32

Hits

30

36

Faceoffs Won

30

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MatchupOverUnder
Bruins 1-1	N/A	N/A
Sabres 1-1	N/A	N/A