Astros vs. Guardians Odds & Betting Predictions - April 20, 2026

Astros at Guardians

10:10 pm • CLEG

Houston Astros

35-41

9 - 2

Cleveland Guardians

40-35

pitcher		team	era	w-l
S.Cecconi			4.60	3-5
S.Arrighetti			2.57	7-2

MatchupOpenSpreadTotalMoneyline
Astros 35-41	+1.5	+1.5-188	o7.5-112	+115
Guardians 40-35	u8.5	-1.5+161	u7.5-108	-135

Monday 10:10 p.m.

April 20, 2026

Progressive FieldCleveland

CLE -125

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HOU +115

0.58u

Bet to +108

HOU +115

1.44u

CLE -114

HOU +102

1.02u

Under 7.5-115

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Y.Alvarez o0.5 HR+450

0.25u

Under 8-118

0.25u

@Tannerstruth ⭐️ https://myaction.app/CL26XueLu2b

S.Arrighetti u4.5 Ks+125

1.25u

There is a value opportunity on Spencer Arrighetti's strikeouts prop. THE BAT X is projecting him to record 4.38 strikeouts, while oddsmakers are implying 4.97. The model believes there is a 56% chance he records fewer than 5 strikeouts, so there is value on the under at +125. This play is good down to at least +106. Love THE BAT X? Get all of Carty's sports betting projections at EV Analytics https://evanalytics.com/subscribe/mlb?ref=zdlkmgz

S.Cecconi u4.5 Hits Allowed+105

0.48u

Under 7.5+100

Under 8.5-128

0.64u

Bet to 7.5 (-102)

CLE -109

1.09u

Astros vs Guardians: Pure Weather Under
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No props found

MLB Public Betting

Guardians are 3-2 in their last 5 games.
Guardians are 4-1 in their last 5 games against the spread
Guardians are 21-18 in their road games against the spread
The totals have gone OVER in 1 of Guardians' last 5 games
The totals have gone OVER in 18 of Guardians' 36 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Guardians	40-35	19-17	21-18	18-23	22-12
Astros	36-40	18-20	18-20	7-16	28-23

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Guardians	36-39	18-18	18-21	21-20	15-19
Astros	39-33-4	22-15-1	17-18-3	13-10	25-22-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Guardians	40-35	19-17	21-18	22-19	18-16
Astros	35-41	18-20	17-21	9-14	25-26

date	opponent	score	spread	over/under	moneyline
Apr 19th	BAL	W 8-4	+1.5 W	O 6.5	CLE -120
Apr 18th	BAL	W 4-2	-1.5 W	U 7.5	CLE -146
Apr 17th	BAL	L 4-6	-1.5 L	O 8	BAL -141
Apr 16th	BAL	W 4-2	-1.5 W	U 8	CLE -136
Apr 15th	@STL	L 3-5	-	U 9	STL -112

Lance McCullers
SP
Lance McCullers Jr. has been scratched Tuesday. Jason Alexander will start.
Out

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PITCHER	PC	IP	K	ER
RS.Arrighetti, P	96	5	3	2
LS.Okert, P	15	1	0	0
RA.Blubaugh, P	15	1	1	0
RJ.Murray, P	39	2	2	0

HITTERS	H-AB	R	HR	RBI
1C.Correa, SS	3-5	1	0	2
2Y.Alvarez, DH	1-5	0	0	0
3J.Altuve, 2B	0-5	0	0	0
4C.Walker, 1B	3-5	3	1	2
5I.Paredes, 3B	3-5	2	2	2
6T.Trammell, CF	1-1	0	0	0
6C.Smith, PR	0-2	1	0	1
6C.Smith, RF	0-2	1	0	1
7Y.Diaz, C	1-4	0	0	1
8D.Harris, RF	0-3	1	0	0
8D.Harris, LF	0-3	1	0	0
9B.Matthews, LF	1-3	1	0	1
9B.Matthews, CF	1-3	1	0	1

PITCHER	PC	IP	K	ER
RS.Cecconi, P	94	5	2	6
RM.Festa, P	22	2	1	1
LT.Herrin, P	19	1	0	0
RC.Brogdon, P	19	1	1	1

HITTERS	H-AB	R	RBI
1S.Kwan, CF	0-4	0	0
2C.DeLauter, RF	0-4	0	0
3J.Ramirez, 3B	1-4	2	0
4K.Manzardo, 1B	1-5	0	0
5R.Hoskins, DH	2-4	0	1
6G.Valera, LF	1-3	0	1
7J.Brito, 2B	0-3	0	0
8B.Naylor, C	0-4	0	0
9B.Rocchio, SS	3-3	0	0