Orioles vs. Guardians Odds & Betting Predictions - April 16, 2026

Orioles at Guardians

10:10 pm • CLEG

Baltimore Orioles

9-9

0 - 2

Cleveland Guardians

10-9

MatchupOpenSpreadTotalMoneyline
Orioles 9-9	+1.5	+1.5-194	o8-102	+115
Guardians 10-9	u8	-1.5+158	u8-114	-136

Thursday 10:10 p.m.

April 16, 2026

Progressive FieldCleveland

BAL +113

📚Onyx

A.Martinez o0.5 Hits-175

CLE -130

0.5u

Under 4.5 (F5)-135

$1.35

Under 0.5 (1st Inn)-135

$1.35

S.Kwan o1.5 Hits + Runs + RBIs-120

CLE -125

P.Messick o5.5 Ks-130

1.3u

CLE -125

1.25u

J.Ramirez o1.5 Total Bases+118

$1.00

J.Ramirez o0.5 HR+564

0.1u

Under 0.5 (1st Inn)-125

1.25u

Under 8-110

1.1u

Under 4.5 (F5)-130

1.3u

BAL +110

P.Messick o16.5 Outs-105

0.53u

S.Baz u4.5 Ks+120

0.42u

C.DeLauter o1.5 Hits + Runs + RBIs-120

1.2u

Over 8-105

0.53u

Bet to 8.5 (+100)

C.DeLauter o1.5 Hits + Runs + RBIs-105

1.05u

CLE -124 (F5)

0.62u

(FD) See Thursday's article. (There are some better numbers out there, but neither DK, nor B365 have it up yet and I'm posting what I got, Wouldn't want to risk losing this line, but wouldn't play it any worse.)

BAL +100

0.5u

Orioles vs Guardians: The F5 Bet to Make on Thursday
Matt Trollo•
Apr 16, 2026 UTC
MLB Best Bets for Thursday
Action Network Staff•
Apr 16, 2026 UTC
Zerillo's Opening Pitch for Thursday
Sean Zerillo•
Apr 16, 2026 UTC

See more MLB Coverage

No props found

MLB Public Betting

Guardians are 2-3 in their last 5 games.
Guardians are 2-3 in their last 5 games against the spread
Guardians are 6-7 in their road games against the spread
The totals have gone OVER in 3 of Guardians' last 5 games
The totals have gone OVER in 2 of Guardians' 6 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Guardians	11-8	5-1	6-7	3-2	8-6
Orioles	7-11	5-7	2-4	6-8	1-3

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Guardians	9-10	2-4	7-6	2-3	7-7
Orioles	10-8	7-5	3-3	7-7	3-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Guardians	10-9	4-2	6-7	3-2	7-7
Orioles	9-9	6-6	3-3	8-6	1-3

date	opponent	score	spread	over/under	moneyline
Apr 15th	@STL	L 3-5	-	U 9	STL -112
Apr 14th	@STL	L 5-6	-1.5 L	O 9	STL -120
Apr 13th	@STL	W 9-3	-1.5 W	O 8	CLE -120
Apr 12th	@ATL	L 1-13	+1.5 L	O 7.5	ATL +164
Apr 11th	@ATL	W 6-0	-1.5 W	U 8	CLE -102

Adley Rutschman
C
Adley Rutschman has been scratched Saturday.
Out
Heston Kjerstad
LF
Kjerstad is out with hamstring
Out
Jordan Westburg
3B
Westburg is out with elbow
Out
Jackson Holliday
2B
Holliday is out with hand
Out

See more MLB Injuries

PITCHER		PC	IP	K	ER
RS.Baz, P		47	3	2	2

HITTERS	H-AB	R	HR	RBI
1T.Ward, LF	0-1	0	0	0
2G.Henderson, DH	0-1	0	0	0
3P.Alonso, 1B	0-1	0	0	0
4J.Rodriguez, RF	0-1	0	0	0
5S.Basallo, C	0-1	0	0	0
6J.Jackson, 2B	0-1	0	0	0
7C.Mayo, 3B	0-1	0	0	0
8L.Taveras, CF	0-1	0	0	0
9B.Alexander, SS	0-1	0	0	0

PITCHER		PC	IP	K	ER
LP.Messick, P		35	3	4	0

HITTERS	H-AB	R	HR	RBI
1S.Kwan, CF	0-2	0	0	0
2C.DeLauter, DH	0-1	1	0	0
3J.Ramirez, 3B	1-2	1	1	2
4K.Manzardo, 1B	0-0	0	0	0
5G.Valera, RF	0-1	0	0	0
6A.Martinez, LF	0-1	0	0	0
7J.Brito, 2B	0-1	0	0	0
8A.Hedges, C	0-1	0	0	0
9B.Rocchio, SS	0-1	0	0	0