Cubs vs. Cardinals Odds & Betting Predictions - May 31, 2026

Cubs at Cardinals

11:20 pm • NBC/Peacock
@
Starting Pitchers
pitcherteameraw-l
Matthew Liberatore logoM.LiberatoreSt. Louis Cardinals logo4.762-3
Jordan Wicks logoJ.WicksChicago Cubs logo16.610-1

Cubs at Cardinals Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
32-27
-1.5
-1.5+165
o8.5-105
-102
Cardinals
30-26
u8.5
+1.5-192
u8.5-114
-118
location pinSunday 11:20 p.m.
May 31, 2026
Busch StadiumSt. Louis
thermometer image82°Fahrenheit
rain image7%Rain
wind image5Wind
Cubs vs. Cardinals Expert Picks
Sandy Plashkes
Sandy Plashkes
Last 30d: 107-110-3 (-9.3u)
Over 8.5-105
2.1u
Picks Office
Picks Office
Last 30d: 134-135-10 (-9.3u)
STL -110
1u
Join Discord for earlier access: https://discord.gg/HjKxYKdSUy Chicago's listed starter has only 4.1 innings this season with a 16.62 ERA and 2.31 WHIP. St. Louis gets the steadier workload profile with Liberatore at 56.2 innings and 11 starts. The Cardinals already lead the season series 2-1, and Chicago is 14-16 away from home.

Cubs vs. Cardinals Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Cubs vs. Cardinals Public Betting Percentages

Away Logo

Cubs

Public

52%

Bets%

48%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cardinals
33-2316-1217-113-330-20
Cubs
24-3512-1712-1815-239-12

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cardinals
24-29-314-13-110-16-22-422-25-3
Cubs
33-2615-1418-1219-1914-7

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cardinals
30-2614-1416-123-327-23
Cubs
32-2718-1114-1622-1610-11

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 30thCHCL 1-6+1.5 LU 8CHC +111
May 29thCHCW 6-5+1.5 WO 7.5STL +113
May 27th@MILL 1-2+1.5 WU 8MIL +149
May 26th@MILL 0-6+1.5 LU 8MIL +179
May 25th@MILL 1-5+1.5 LU 7.5MIL +193

Cubs vs. Cardinals Injury Updates

Cubs Injuries

  • Tyler Austin
    1B

    Austin is out with knee

    Out

  • Justin Steele
    SP

    Steele is out with elbow

    Out

Cardinals Injuries

  • Lars Nootbaar
    LF

    Nootbaar is out with heel

    Out

Cubs vs. Cardinals Starting Lineups
Cubs Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Jordan Wicks logoLJ.Wicks, P0-116.612.30810.38
HITTERSAVGOBPSLGHR
Nico Hoerner logo1N.Hoerner, 2B.252.336.3594
Alex Bregman logo2A.Bregman, 3B.260.342.3534
Ian Happ logo3I.Happ, LF.234.355.47813
Seiya Suzuki logo4S.Suzuki, DH.250.339.4057
Michael Busch logo5M.Busch, 1B.238.368.3866
Carson Kelly logo6C.Kelly, C.297.378.3842
Dansby Swanson logo7D.Swanson, SS.185.293.3337
Pete Crow-Armstrong logo8P.Crow-Armstrong, CF.237.327.3917
Kevin Alcantara logo9K.Alcantara, RF.000.250.0000
Cardinals Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Matthew Liberatore logoLM.Liberatore, P2-34.761.5718.42
HITTERSAVGOBPSLGHR
JJ Wetherholt logo1J.Wetherholt, 2B.244.356.4049
Ivan Herrera logo2I.Herrera, C.260.386.4287
Jordan Walker logo3J.Walker, RF.290.359.55715
Nelson Velazquez logo4N.Velazquez, DH.667.750.6671
Alec Burleson logo5A.Burleson, 1B.280.347.4397
Masyn Winn logo6M.Winn, SS.234.313.3151
Jose Fermin logo7J.Fermin, LF.231.301.3852
Thomas Saggese logo8T.Saggese, 3B.169.224.2391
Victor Scott logo9V.Scott, CF.187.255.2522

Cubs vs. Cardinals Odds Comparison

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Cubs at Cardinals Team Totals

MatchupOverUnder
Cubs
32-27
N/A
N/A
Cardinals
30-26
N/A
N/A