Giants vs. Padres Odds & Betting Predictions - August 21, 2025

Giants at Padres

8:10 pm • SDPA

San Francisco Giants

0-0

4 - 8

San Diego Padres

1-2

pitcher		team	era	w-l
D.Cease			4.55	8-12
J.Verlander			3.85	4-11

MatchupOpenSpreadTotalMoneyline
Giants 0-0	+1.5	+1.5-134	o8-111	+161
Padres 1-2	u8	-1.5+109	u8-111	-193

Thursday 8:10 p.m.

August 21, 2025

PETCO ParkSan Diego

SF +164

0.5u

SD -1.5+130

1.3u

Over 7.5-120

0.83u

SD -1.5+115

2.3u

Under 0.5 (1st Inn)-120

Under 8-118

0.59u

Under is popping in the Action models so I’ll bite

Under 8-118

0.59u

Under 8-110

0.55u

Bet to -115

SD -150 (F5)

0.25u

Small to -165

Dodgers vs Padres: The F5 Bet to Make Saturday
Doug Ziefel•
Aug 23, 2025 UTC
Giants vs Padres: Thursday Afternoon Over/Under Pick
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No props found

MLB Public Betting

Padres are 4-1 in their last 5 games.
Padres are 4-1 in their last 5 games against the spread
Padres are 42-39 in their road games against the spread
The totals have gone OVER in 2 of Padres' last 5 games
The totals have gone OVER in 34 of Padres' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Padres	87-75	45-36	42-39	44-49	42-26
Giants	76-86	35-46	41-40	35-57	40-28

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Padres	69-89-4	34-46-1	35-43-3	46-45-2	23-43-2
Giants	75-80-7	35-45-1	40-35-6	36-55-1	37-25-6

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Padres	90-72	52-29	38-43	56-37	33-35
Giants	81-81	42-39	39-42	49-43	31-37

date	opponent	score	spread	over/under	moneyline
Aug 21st	SF	W 8-1	-1.5 W	O 8	SD -140
Aug 20th	SF	W 5-1	-1.5 W	U 8	SD -189
Aug 19th	SF	L 3-4	-1.5 L	U 7.5	SF -149
Aug 17th	@LAD	L 4-5	+1.5 W	O 8.5	LAD +120
Aug 17th	@LAD	L 0-6	+1.5 L	U 7.5	LAD +103

Joe Musgrove
SP
Musgrove is out for season with elbow
Out for Season

See more MLB Injuries

PITCHER	PC	IP	K	ER
RJ.Verlander, P	91	4.1	4	7
LM.Gage, P	17	0.2	1	1
RJ.Peguero, P	32	2	1	0
RS.Bivens, P	10	1	1	0

HITTERS	H-AB	R	HR	RBI
1J.Lee, CF	1-3	0	0	0
2H.Ramos, LF	0-4	0	0	0
3R.Devers, DH	1-4	1	1	1
4W.Adames, SS	1-2	1	1	1
5D.Smith, 1B	0-3	0	0	0
5W.Flores, PH	0-1	0	0	0
5W.Flores, 1B	0-1	0	0	0
6C.Schmitt, 3B	1-3	0	0	0
7C.Koss, 2B	0-4	0	0	0
8L.Matos, RF	2-4	1	0	0
9A.Knizner, C	1-3	1	0	1
9P.Bailey, PH	0-1	0	0	0

PITCHER	PC	IP	K	ER
RD.Cease, P	95	5	7	4
RJ.Estrada, P	24	1.1	1	0
LA.Morejon, P	14	1	0	0
RM.Miller, P	5	0.2	1	0
RR.Suarez, P	13	1	2	0

HITTERS	H-AB	R	RBI
1F.Tatis, RF	2-5	2	0
2L.Arraez, 1B	2-4	1	0
3M.Machado, 3B	2-4	1	3
4R.O'Hearn, DH	0-2	1	0
5X.Bogaerts, SS	1-3	0	2
6G.Sheets, LF	0-3	0	0
6B.Johnson, CF	1-1	0	0
7R.Laureano, CF	2-4	1	1
7R.Laureano, LF	2-4	1	1
8J.Cronenworth, 2B	0-3	1	0
9F.Fermin, C	1-4	1	0